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O79552

- COX3_LYCSM

UniProt

O79552 - COX3_LYCSM

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Protein

Cytochrome c oxidase subunit 3

Gene

MT-CO3

Organism
Lycodon semicarinatus (Ryukyu odd-tooth snake) (Eumesodon semicarinatus)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Subunits I, II and III form the functional core of the enzyme complex.

Catalytic activityi

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

GO - Molecular functioni

  1. cytochrome-c oxidase activity Source: UniProtKB-EC

GO - Biological processi

  1. aerobic electron transport chain Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome c oxidase subunit 3 (EC:1.9.3.1)
Alternative name(s):
Cytochrome c oxidase polypeptide III
Gene namesi
Name:MT-CO3
Synonyms:COIII, COXIII, MTCO3
Encoded oniMitochondrion
OrganismiLycodon semicarinatus (Ryukyu odd-tooth snake) (Eumesodon semicarinatus)
Taxonomic identifieri56549 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiLepidosauriaSquamataBifurcataUnidentataEpisquamataToxicoferaSerpentesColubroideaColubridaeColubrinaeLycodon

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei15 – 3521HelicalSequence AnalysisAdd
BLAST
Transmembranei42 – 6221HelicalSequence AnalysisAdd
BLAST
Transmembranei81 – 10121HelicalSequence AnalysisAdd
BLAST
Transmembranei159 – 17921HelicalSequence AnalysisAdd
BLAST
Transmembranei197 – 21721HelicalSequence AnalysisAdd
BLAST
Transmembranei239 – 25921HelicalSequence AnalysisAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. mitochondrial inner membrane Source: UniProtKB-KW
  3. respiratory chain complex IV Source: UniProtKB
Complete GO annotation...

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 261261Cytochrome c oxidase subunit 3PRO_0000183766Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliO79552.
SMRiO79552. Positions 1-261.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

HOVERGENiHBG016686.

Family and domain databases

Gene3Di1.20.120.80. 1 hit.
InterProiIPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
IPR000298. Cyt_c_oxidase_su3_dom.
[Graphical view]
PANTHERiPTHR11403. PTHR11403. 1 hit.
PfamiPF00510. COX3. 1 hit.
[Graphical view]
SUPFAMiSSF81452. SSF81452. 1 hit.
PROSITEiPS50253. COX3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O79552-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTHQLHQYHL VDPSPWPLTG AMGSLLLASG LAVWFHTNNT MLLKFGLLTL
60 70 80 90 100
LLTMFQWWRD IIRESTYQGH HTSGVQKNMR YGMILFITSE VFFFLGFFWA
110 120 130 140 150
LYHVSLVPTP ELGAEWPPIG ITPLNPMEVP LLNTAVLLSS GATITWSHHT
160 170 180 190 200
MMKGNKKEAT HALMLTIILG AYFTALQLSE YMETPFTIAD SVYGSLFFVA
210 220 230 240 250
TGFHGLHVMI GTSFLMVCAL RLAKHHFTIT HHFGYEAAIW YWHFVDIVWL
260
FLYISVYWWG S
Length:261
Mass (Da):29,892
Last modified:November 1, 1998 - v1
Checksum:i0E8A7A8953FF3868
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB008539 Genomic DNA. Translation: BAA33028.1.
PIRiT11094.
RefSeqiNP_008425.1. NC_001945.1.

Genome annotation databases

GeneIDi808271.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB008539 Genomic DNA. Translation: BAA33028.1 .
PIRi T11094.
RefSeqi NP_008425.1. NC_001945.1.

3D structure databases

ProteinModelPortali O79552.
SMRi O79552. Positions 1-261.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 808271.

Organism-specific databases

CTDi 4514.

Phylogenomic databases

HOVERGENi HBG016686.

Family and domain databases

Gene3Di 1.20.120.80. 1 hit.
InterProi IPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
IPR000298. Cyt_c_oxidase_su3_dom.
[Graphical view ]
PANTHERi PTHR11403. PTHR11403. 1 hit.
Pfami PF00510. COX3. 1 hit.
[Graphical view ]
SUPFAMi SSF81452. SSF81452. 1 hit.
PROSITEi PS50253. COX3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The complete nucleotide sequence of a snake (Dinodon semicarinatus) mitochondrial genome with two identical control regions."
    Kumazawa Y., Ota H., Nishida M., Ozawa T.
    Genetics 150:313-329(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Tissue: Liver.

Entry informationi

Entry nameiCOX3_LYCSM
AccessioniPrimary (citable) accession number: O79552
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 1, 2001
Last sequence update: November 1, 1998
Last modified: October 29, 2014
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3