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O79552 (COX3_DINSE) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 74. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Cytochrome c oxidase subunit 3

EC=1.9.3.1
Alternative name(s):
Cytochrome c oxidase polypeptide III
Gene names
Name:MT-CO3
Synonyms:COIII, COXIII, MTCO3
Encoded onMitochondrion
OrganismDinodon semicarinatum (Ryukyu odd-tooth snake) (Eumesodon semicarinatus)
Taxonomic identifier56549 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiLepidosauriaSquamataBifurcataUnidentataEpisquamataToxicoferaSerpentesColubroideaColubridaeColubrinaeDinodon

Protein attributes

Sequence length261 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Subunits I, II and III form the functional core of the enzyme complex.

Catalytic activity

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

Subcellular location

Mitochondrion inner membrane; Multi-pass membrane protein By similarity.

Sequence similarities

Belongs to the cytochrome c oxidase subunit 3 family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 261261Cytochrome c oxidase subunit 3
PRO_0000183766

Regions

Transmembrane15 – 3521Helical; Potential
Transmembrane42 – 6221Helical; Potential
Transmembrane81 – 10121Helical; Potential
Transmembrane159 – 17921Helical; Potential
Transmembrane197 – 21721Helical; Potential
Transmembrane239 – 25921Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
O79552 [UniParc].

Last modified November 1, 1998. Version 1.
Checksum: 0E8A7A8953FF3868

FASTA26129,892
        10         20         30         40         50         60 
MTHQLHQYHL VDPSPWPLTG AMGSLLLASG LAVWFHTNNT MLLKFGLLTL LLTMFQWWRD 

        70         80         90        100        110        120 
IIRESTYQGH HTSGVQKNMR YGMILFITSE VFFFLGFFWA LYHVSLVPTP ELGAEWPPIG 

       130        140        150        160        170        180 
ITPLNPMEVP LLNTAVLLSS GATITWSHHT MMKGNKKEAT HALMLTIILG AYFTALQLSE 

       190        200        210        220        230        240 
YMETPFTIAD SVYGSLFFVA TGFHGLHVMI GTSFLMVCAL RLAKHHFTIT HHFGYEAAIW 

       250        260 
YWHFVDIVWL FLYISVYWWG S 

« Hide

References

[1]"The complete nucleotide sequence of a snake (Dinodon semicarinatus) mitochondrial genome with two identical control regions."
Kumazawa Y., Ota H., Nishida M., Ozawa T.
Genetics 150:313-329(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Tissue: Liver.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AB008539 Genomic DNA. Translation: BAA33028.1.
PIRT11094.
RefSeqNP_008425.1. NC_001945.1.

3D structure databases

ProteinModelPortalO79552.
SMRO79552. Positions 1-261.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID808271.

Organism-specific databases

CTD4514.

Phylogenomic databases

HOVERGENHBG016686.
ProtClustDBMTH00118.

Family and domain databases

Gene3D1.20.120.80. 1 hit.
InterProIPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR000298. Cyt_c_oxidase_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
[Graphical view]
PANTHERPTHR11403. PTHR11403. 1 hit.
PfamPF00510. COX3. 1 hit.
[Graphical view]
SUPFAMSSF81452. SSF81452. 1 hit.
PROSITEPS50253. COX3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCOX3_DINSE
AccessionPrimary (citable) accession number: O79552
Entry history
Integrated into UniProtKB/Swiss-Prot: June 1, 2001
Last sequence update: November 1, 1998
Last modified: April 16, 2014
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families