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O78497

- HO_GUITH

UniProt

O78497 - HO_GUITH

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Protein

Heme oxygenase

Gene
pbsA
Organism
Guillardia theta (Cryptomonas phi)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the opening of the heme ring with the release of iron. Key enzyme in the synthesis of the chromophoric part of the photosynthetic antennae.

Catalytic activityi

Protoheme + 3 AH2 + 3 O2 = biliverdin + Fe2+ + CO + 3 A + 3 H2O.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi17 – 171Iron (heme axial ligand) By similarity

GO - Molecular functioni

  1. heme oxygenase (decyclizing) activity Source: UniProtKB-EC
  2. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. heme oxidation Source: InterPro
  2. photosynthesis Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Photosynthesis

Keywords - Ligandi

Heme, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Heme oxygenase (EC:1.14.99.3)
Gene namesi
Name:pbsA
Encoded oniPlastid; Chloroplast
OrganismiGuillardia theta (Cryptomonas phi)
Taxonomic identifieri55529 [NCBI]
Taxonomic lineageiEukaryotaCryptophytaPyrenomonadalesGeminigeraceaeGuillardia

Subcellular locationi

GO - Cellular componenti

  1. chloroplast Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Chloroplast, Plastid

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 237237Heme oxygenasePRO_0000209698Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliO78497.
SMRiO78497. Positions 2-218.

Family & Domainsi

Sequence similaritiesi

Belongs to the heme oxygenase family.

Phylogenomic databases

HOGENOMiHOG000233221.
OMAiMDRNKDH.

Family and domain databases

Gene3Di1.20.910.10. 1 hit.
InterProiIPR002051. Haem_Oase.
IPR016053. Haem_Oase-like.
IPR016084. Haem_Oase-like_multi-hlx.
IPR018207. Haem_oxygenase_CS.
[Graphical view]
PANTHERiPTHR10720. PTHR10720. 1 hit.
PfamiPF01126. Heme_oxygenase. 1 hit.
[Graphical view]
PIRSFiPIRSF000343. Haem_Oase. 1 hit.
PRINTSiPR00088. HAEMOXYGNASE.
SUPFAMiSSF48613. SSF48613. 1 hit.
PROSITEiPS00593. HEME_OXYGENASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O78497-1 [UniParc]FASTAAdd to Basket

« Hide

MSNNLAIQLR EGTSKSHSMA ENVSFVKSFL SGVIDTNSYK KMMSNLYFVY    50
KAMEEEMEYH KENDLIKPIY FVELNRSESL ALDLNFYYGD TWKDIIEPSE 100
ATRVYINRIK KISKEKPLLL IAHAYTRYLG DLSGGQILKK IAQRALNVPN 150
SQGLAFYEFD KIDDEQAFKQ KYKKALDTLP VTDKMISQIV AEANIAFNLN 200
MRMFQELEMS YIRIFTKILM QFLINSKDKL RVMLNFS 237
Length:237
Mass (Da):27,631
Last modified:November 1, 1998 - v1
Checksum:iCBDD4D045A7B8890
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF041468 Genomic DNA. Translation: AAC35688.1.
RefSeqiNP_050754.1. NC_000926.1.

Genome annotation databases

GeneIDi857059.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF041468 Genomic DNA. Translation: AAC35688.1 .
RefSeqi NP_050754.1. NC_000926.1.

3D structure databases

ProteinModelPortali O78497.
SMRi O78497. Positions 2-218.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 857059.

Phylogenomic databases

HOGENOMi HOG000233221.
OMAi MDRNKDH.

Family and domain databases

Gene3Di 1.20.910.10. 1 hit.
InterProi IPR002051. Haem_Oase.
IPR016053. Haem_Oase-like.
IPR016084. Haem_Oase-like_multi-hlx.
IPR018207. Haem_oxygenase_CS.
[Graphical view ]
PANTHERi PTHR10720. PTHR10720. 1 hit.
Pfami PF01126. Heme_oxygenase. 1 hit.
[Graphical view ]
PIRSFi PIRSF000343. Haem_Oase. 1 hit.
PRINTSi PR00088. HAEMOXYGNASE.
SUPFAMi SSF48613. SSF48613. 1 hit.
PROSITEi PS00593. HEME_OXYGENASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The plastid genome of the cryptophyte alga, Guillardia theta: complete sequence and conserved synteny groups confirm its common ancestry with red algae."
    Douglas S.E., Penny S.L.
    J. Mol. Evol. 48:236-244(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Entry informationi

Entry nameiHO_GUITH
AccessioniPrimary (citable) accession number: O78497
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: November 1, 1998
Last modified: May 14, 2014
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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