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Protein

60 kDa chaperonin, chloroplastic

Gene

groL

Organism
Guillardia theta (Cryptomonas phi)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperone
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
60 kDa chaperonin, chloroplasticUniRule annotation
Alternative name(s):
GroEL proteinUniRule annotation
Protein Cpn60UniRule annotation
Gene namesi
Name:groLUniRule annotation
Synonyms:groELUniRule annotation
Encoded oniPlastid; Chloroplast
OrganismiGuillardia theta (Cryptomonas phi)
Taxonomic identifieri55529 [NCBI]
Taxonomic lineageiEukaryotaCryptophytaPyrenomonadalesGeminigeraceaeGuillardia

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Chloroplast, Plastid

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000636251 – 52960 kDa chaperonin, chloroplasticAdd BLAST529

Proteomic databases

PRIDEiO78419.

Interactioni

Subunit structurei

Oligomer of 14 subunits composed of two stacked rings of 7 subunits.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliO78419.
SMRiO78419.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the chaperonin (HSP60) family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000076290.

Family and domain databases

CDDicd03344. GroEL. 1 hit.
Gene3Di1.10.560.10. 2 hits.
3.50.7.10. 1 hit.
HAMAPiMF_00600. CH60. 1 hit.
InterProiView protein in InterPro
IPR018370. Chaperonin_Cpn60_CS.
IPR001844. Chaprnin_Cpn60.
IPR002423. Cpn60/TCP-1.
IPR027409. GroEL-like_apical_dom_sf.
IPR027413. GROEL-like_equatorial_sf.
PANTHERiPTHR11353. PTHR11353. 1 hit.
PfamiView protein in Pfam
PF00118. Cpn60_TCP1. 1 hit.
PRINTSiPR00298. CHAPERONIN60.
SUPFAMiSSF48592. SSF48592. 3 hits.
SSF52029. SSF52029. 1 hit.
TIGRFAMsiTIGR02348. GroEL. 1 hit.
PROSITEiView protein in PROSITE
PS00296. CHAPERONINS_CPN60. 1 hit.

Sequencei

Sequence statusi: Complete.

O78419-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSKIILYQED ARRALERGMD ILAEAVSVTL GPKGRNVVLE RKYGAPQIVN
60 70 80 90 100
DGVTIAKEIE LEDHIENTGV ALIRQAASKT NDVAGDGTTT ATVLAHAMVK
110 120 130 140 150
QGMKNVAAGA NAIALKRGIE KATQFIVTQI AEYARPVEDT RAISQVASIS
160 170 180 190 200
AGNDIETGKM IADAIDKVGR EGVISLEEGK STITELEMTE GMCFEKGFIS
210 220 230 240 250
PYFVTDTERM EVIQDNPYIL LTDKKITLVQ QELLPTLELI SKTSRPLVII
260 270 280 290 300
AEDVEKEALA TLVVNKLRGI VNVVAVRAPG FGDRRKAMLE DIAILTGGQV
310 320 330 340 350
ISEDAGFSLE TLTLDMLGQA RRITITKENT TIIAEGNEKD VKSRCEQIRR
360 370 380 390 400
QIEASDSSYE REKLQERLAK LAGGVAVIKV GAATETEMKD KKLRLEDAIN
410 420 430 440 450
ATKAAVEEGI VPGGGSTLTH LANDLKDWAE DNLIEDELIG ALIVERSLTS
460 470 480 490 500
PLRRIIENTG QNSAIIIEQI KESEFNIGYD AAKGEIVDMY DVGIIDPAKV
510 520
TRSGLQNAAS IASMILTTEC IVVDKQDEK
Length:529
Mass (Da):57,403
Last modified:November 1, 1998 - v1
Checksum:i161AC0ACD91F237C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF041468 Genomic DNA. Translation: AAC35604.1.
RefSeqiNP_050670.1. NC_000926.1.

Genome annotation databases

GeneIDi856959.

Similar proteinsi

Entry informationi

Entry nameiCH60_GUITH
AccessioniPrimary (citable) accession number: O78419
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: November 1, 1998
Last modified: November 22, 2017
This is version 86 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families