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O78208 (O78208_HUMAN) Unreviewed, UniProtKB/TrEMBL

Last modified March 19, 2014. Version 62. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein attributes

Sequence length71 AA.
Sequence statusFragment.
Protein existenceEvidence at transcript level

Ontologies

Keywords
   PTMDisulfide bond SAAS SAAS000716
Gene Ontology (GO)
   Biological_processactivation of MAPK activity

Inferred from electronic annotation. Source: Ensembl

antigen processing and presentation of exogenous peptide antigen via MHC class II

Inferred from electronic annotation. Source: Ensembl

chaperone mediated protein folding requiring cofactor

Inferred from electronic annotation. Source: Ensembl

defense response

Inferred from electronic annotation. Source: Ensembl

immunoglobulin mediated immune response

Inferred from electronic annotation. Source: Ensembl

intracellular protein transport

Inferred from electronic annotation. Source: Ensembl

macrophage migration inhibitory factor signaling pathway

Inferred from electronic annotation. Source: Ensembl

negative regulation of DNA damage response, signal transduction by p53 class mediator

Inferred from electronic annotation. Source: Ensembl

negative regulation of T cell differentiation

Inferred from electronic annotation. Source: Ensembl

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

Inferred from electronic annotation. Source: Ensembl

negative regulation of mature B cell apoptotic process

Inferred from electronic annotation. Source: Ensembl

negative thymic T cell selection

Inferred from electronic annotation. Source: Ensembl

positive regulation of ERK1 and ERK2 cascade

Inferred from electronic annotation. Source: Ensembl

positive regulation of T cell differentiation

Inferred from electronic annotation. Source: Ensembl

positive regulation of chemokine (C-X-C motif) ligand 2 production

Inferred from electronic annotation. Source: Ensembl

positive regulation of cytokine-mediated signaling pathway

Inferred from electronic annotation. Source: Ensembl

positive regulation of dendritic cell antigen processing and presentation

Inferred from electronic annotation. Source: Ensembl

positive regulation of macrophage cytokine production

Inferred from electronic annotation. Source: Ensembl

positive regulation of neutrophil chemotaxis

Inferred from electronic annotation. Source: Ensembl

positive regulation of peptidyl-tyrosine phosphorylation

Inferred from electronic annotation. Source: Ensembl

positive regulation of type 2 immune response

Inferred from electronic annotation. Source: Ensembl

positive thymic T cell selection

Inferred from electronic annotation. Source: Ensembl

protein complex assembly

Inferred from electronic annotation. Source: Ensembl

   Cellular_componentGolgi apparatus

Inferred from electronic annotation. Source: Ensembl

MHC class II protein complex

Inferred from electronic annotation. Source: Ensembl

NOS2-CD74 complex

Inferred from electronic annotation. Source: Ensembl

endoplasmic reticulum

Inferred from electronic annotation. Source: Ensembl

external side of plasma membrane

Inferred from electronic annotation. Source: Ensembl

lysosome

Inferred from electronic annotation. Source: Ensembl

macrophage migration inhibitory factor receptor complex

Inferred from electronic annotation. Source: Ensembl

multivesicular body

Inferred from electronic annotation. Source: Ensembl

   Molecular_functioncytokine receptor activity

Inferred from electronic annotation. Source: Ensembl

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Experimental info

Non-terminal residue11 EMBL AAA35996.1
Non-terminal residue711 EMBL AAA35996.1

Sequences

Sequence LengthMass (Da)Tools
O78208 [UniParc].

Last modified November 1, 1998. Version 1.
Checksum: ABFC8EC5571D3C48

FASTA717,916
        10         20         30         40         50         60 
PPKVLTKCQE EVSHIPAVHP GSFRPKCDEN GNYLPLQCYG SIGYCWCVFP NGTEVPNTRS 

        70 
RGHHNCSESL E 

« Hide

References

[1]"Four Ia invariant chain forms derive from a single gene by alternate splicing and alternate initiation of transcription/translation."
O'Sullivan D.M., Noonan D., Quaranta V.
J. Exp. Med. 166:444-460(1987) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
[2]"Purification of the complex of cathepsin L and the MHC class II-associated invariant chain fragment from human kidney."
Ogrinc T., Dolenc I., Ritonja A., Turk V.
FEBS Lett. 336:555-559(1993) [PubMed] [Europe PMC] [Abstract]
Cited for: PROTEIN SEQUENCE.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
M28590 mRNA. Translation: AAA35996.1.
PIRI70687.
E27011. S40464.
UniGeneHs.436568.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEO78208.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Gene expression databases

ArrayExpressO78208.
BgeeO78208.

Family and domain databases

Gene3D4.10.800.10. 1 hit.
InterProIPR022339. MHC_II-assoc_invar_chain.
IPR000716. Thyroglobulin_1.
[Graphical view]
PANTHERPTHR14093. PTHR14093. 1 hit.
PfamPF00086. Thyroglobulin_1. 1 hit.
[Graphical view]
SMARTSM00211. TY. 1 hit.
[Graphical view]
SUPFAMSSF57610. SSF57610. 1 hit.
PROSITEPS00484. THYROGLOBULIN_1_1. 1 hit.
PS51162. THYROGLOBULIN_1_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameO78208_HUMAN
AccessionPrimary (citable) accession number: O78208
Entry history
Integrated into UniProtKB/TrEMBL: November 1, 1998
Last sequence update: November 1, 1998
Last modified: March 19, 2014
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.