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Protein

Acyl carrier protein

Gene

acpP

Organism
Toxoplasma gondii
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Carrier of the growing fatty acid chain in fatty acid biosynthesis.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi103 – 1031Zinc 1Combined sources
Metal bindingi108 – 1081Zinc 2Combined sources
Metal bindingi112 – 1121Zinc 2Combined sources
Metal bindingi176 – 1761Zinc 1Combined sources

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Fatty acid biosynthesisUniRule annotation, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism

Keywords - Ligandi

Metal-bindingCombined sources, ZincCombined sources

Names & Taxonomyi

Protein namesi
Recommended name:
Acyl carrier proteinUniRule annotation
Gene namesi
Name:acpPImported
OrganismiToxoplasma gondiiImported
Taxonomic identifieri5811 [NCBI]
Taxonomic lineageiEukaryotaAlveolataApicomplexaConoidasidaCoccidiaEucoccidioridaEimeriorinaSarcocystidaeToxoplasma

Organism-specific databases

EuPathDBiToxoDB:TGME49_264080.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2727Sequence analysisAdd
BLAST
Chaini28 – 183156Acyl carrier proteinSequence analysisPRO_5006963638Add
BLAST

Keywords - PTMi

PhosphopantetheineUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi5811.TGME49_064080.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2QNWX-ray1.90A100-180[»]
SMRiO77470. Positions 101-180.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini106 – 17671Acyl carrierInterPro annotationAdd
BLAST

Sequence similaritiesi

Contains 1 acyl carrier domain.UniRule annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG1748. Eukaryota.
COG0236. LUCA.

Family and domain databases

Gene3Di1.10.1200.10. 1 hit.
HAMAPiMF_01217. Acyl_carrier.
InterProiIPR003231. Acyl_carrier.
IPR009081. PP-bd_ACP.
[Graphical view]
PfamiPF00550. PP-binding. 1 hit.
[Graphical view]
ProDomiPD000887. PD000887. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF47336. SSF47336. 1 hit.
TIGRFAMsiTIGR00517. acyl_carrier. 1 hit.
PROSITEiPS50075. ACP_DOMAIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

O77470-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEMHPRNAGR KTLLALALFM ATSIASSYGF VSPGLIRFNY RYGTCPNMSS
60 70 80 90 100
GVCATPSTAS LGTLGQPAGT VARRPGPFRS VSANVIGSPS SALFAADEAS
110 120 130 140 150
SDDRPLLERV KDVVADQLGV DRARINPESN FIKDLDADSL DSVELVMAFE
160 170 180
EKFGVSIPDE EASKIATVQD ALSYIEKAKS ATA
Length:183
Mass (Da):19,380
Last modified:November 1, 1998 - v1
Checksum:i31A8E76821FE2F59
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF038922 Genomic DNA. Translation: AAC63953.1.
AF038925 mRNA. Translation: AAC63956.1.

Genome annotation databases

EnsemblProtistsiEPR62545; EPR62545; TGGT1_264080.
ESS31831; ESS31831; TGVEG_264080.
KEGGitgo:TGME49_064080.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF038922 Genomic DNA. Translation: AAC63953.1.
AF038925 mRNA. Translation: AAC63956.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2QNWX-ray1.90A100-180[»]
SMRiO77470. Positions 101-180.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi5811.TGME49_064080.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsiEPR62545; EPR62545; TGGT1_264080.
ESS31831; ESS31831; TGVEG_264080.
KEGGitgo:TGME49_064080.

Organism-specific databases

EuPathDBiToxoDB:TGME49_264080.

Phylogenomic databases

eggNOGiKOG1748. Eukaryota.
COG0236. LUCA.

Family and domain databases

Gene3Di1.10.1200.10. 1 hit.
HAMAPiMF_01217. Acyl_carrier.
InterProiIPR003231. Acyl_carrier.
IPR009081. PP-bd_ACP.
[Graphical view]
PfamiPF00550. PP-binding. 1 hit.
[Graphical view]
ProDomiPD000887. PD000887. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF47336. SSF47336. 1 hit.
TIGRFAMsiTIGR00517. acyl_carrier. 1 hit.
PROSITEiPS50075. ACP_DOMAIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: RHImported.
  2. "Toxoplasma gondii apicoplast-targeted acyl carrier protein."
    Lunin V.V., Wernimont A., Lew J., Qiu W., Lin L., Hassanali A., Kozieradzki I., Zhao Y., Schapira M., Bochkarev A., Weigelt J., Sundstrom M., Arrowsmith C.H., Edwards A., Hui R., Brokx S.
    Submitted (JUL-2007) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (1.90 ANGSTROMS) OF 100-180 IN COMPLEX WITH ZINC.

Entry informationi

Entry nameiO77470_TOXGO
AccessioniPrimary (citable) accession number: O77470
Secondary accession number(s): B6KAJ5
, B9Q0Y1, B9QNT2, S7UXV2, S8F8G2
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1998
Last sequence update: November 1, 1998
Last modified: June 8, 2016
This is version 107 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.