O77368 (O77368_PLAF7) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
P-type ATPase, putative EMBL CAB11124.1
EC=3.6.3.- EMBL CAB11124.1

Gene names

Name:	PfATPase7 EMBL CAB11124.1
ORF Names:	PFC0840w EMBL CAB11124.1

Organism

Plasmodium falciparum (isolate 3D7)

Taxonomic identifier

36329 [NCBI]

Taxonomic lineage

Eukaryota › Alveolata › Apicomplexa › Aconoidasida › Haemosporida › Plasmodium › Plasmodium (Laverania)

Protein attributes

Sequence length	1864 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the cation transport ATPase (P-type) family. RuleBase RU000653

Ontologies

Keywords
Cellular component	Membrane
Domain	Transmembrane Transmembrane helix SAAS SAAS023306
Ligand	ATP-binding RuleBase RU000653 Nucleotide-binding
Molecular function	Hydrolase RuleBase RU000653 EMBL CAB11124.1
PTM	Phosphoprotein RuleBase RU000653
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	cation transport Inferred from electronic annotation. Source: InterPro
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	O77368 [UniParc]. Last modified November 1, 1998. Version 1. Checksum: 6A425F4410B1E667	FASTA	1,864	218,020
	10 20 30 40 50 60 MKILEWISCT IKGKHNENKI YLISNFEFNK DDHEYYIKNA ENRIKEEDLN IDIIYGKKHK 70 80 90 100 110 120 NEIRTAKYKL YSFLPLIVFF QFLRLGNLYF LSISMLQLIP EITDSKGMPT YLIPLVFIIV 130 140 150 160 170 180 VAMIKEFFED WQRHKSDNEE NSKKTMVFVQ GELKEKKWAD VKDGDVVKIF SYEYFPADLI 190 200 210 220 230 240 VLNCSNKKGI VNIETKNVDG ESNVKQKYCL PDISKYFSDD KTAGFCRIEL ISERPNDNIF 250 260 270 280 290 300 DYKGYMILPP LQYKNMKNGK LIHFYNTHYK MDDHKDEHDE KGTGKYINKN YKNDYNDKHI 310 320 330 340 350 360 SYNTNEQNNL SDMTKNDPKE YDYNPQNEIN NNNNNNNCDN NNNNCNNNNR FFVDDIKKQG 370 380 390 400 410 420 QNEETVDKKK SFFIINNQKK VYDTGSSNND QITHINNDVI SEKKRASRRR TLYNKLTFNK 430 440 450 460 470 480 SFFNNKNENK KLNKRNSTLS SINNNNDNNN NNNNNNNNIH NREYDGEEQT LKKENFFFKE 490 500 510 520 530 540 YKRDQKFVQI TIDNLVLRGT SLVNTKWIYG LVINTGNRTK LMKNASTKSR QKWSRLEFVY 550 560 570 580 590 600 GNHVIVLIIC QVFISLIVAI AGVLWMRRKG YTLWYLNLDQ TSDSLKTFFI TIGSMVLLFG 610 620 630 640 650 660 SFIPVDLLLI WEVVRLLQGY LINWDNDMYS EKTGRHALSK AGQLLEEMGN VTHIYSDKTG 670 680 690 700 710 720 TLTQNVMQLQ NIGLGNKGTY GFYDFSNIKE NITKSRHWGS QDPMDPVLEE YENEENVYSN 730 740 750 760 770 780 VNDDNKNDHG TNESDDNNNN NNNNDDDDHH DNNHNIHNDQ NNNAQYDNYD NYYLNNHQQQ 790 800 810 820 830 840 NKVKNRPCID DETNFYRNNN MNKERTRKSY TFLNPLNWSN TSINTKMKKK KSLFYNKNSL 850 860 870 880 890 900 ANYESLLNNT YTEDDFIRGE NEFVFFNRIL FVNKIYSIRH DVQDQIYFLL LVLSLCHSAM 910 920 930 940 950 960 IRNVDIDEMD NNEDDNNNNE KLKIYDKETD IVYTYITQTQ PQYDASSPDE LALISTSLYL 970 980 990 1000 1010 1020 GCEFVNRPNL TTIEIELTST FAQRFILGEK KFEKFLEKKE FYEKEFDTYF PDISACLGKE 1030 1040 1050 1060 1070 1080 KKKDNNKINE MINNKGNTKD DYMNNFHMSI PIKNIFGSNK MQYKEEIKYE EKIIKKVVPI 1090 1100 1110 1120 1130 1140 LSFEILDVFA FDNVRKRMSL IVKNEKKEIF MLVKGADTSV LKLASKNQEN IVDHVEHQLH 1150 1160 1170 1180 1190 1200 AFATSGLRTL VLGYKYLTEN EFSDMYRNHI NARKKSETDK EEYLQEFYEE AENNLIIIGC 1210 1220 1230 1240 1250 1260 TGIDDKLQDD VPQVIQDLRD AGMTICVLTG DKLETAINIG HSINILNKQT YNAIFTETDP 1270 1280 1290 1300 1310 1320 TLLLEQLNIH EKNTNAANLL NVDHGTKWWN SVNWEHLNLD LRSETILNFM KSNFHGSLKK 1330 1340 1350 1360 1370 1380 SIISSNMFNM KNNNSFPSLA RQDKVFNSFL ESSESFCHNN NEMDKTKGKE KVHYSQFSIT 1390 1400 1410 1420 1430 1440 ITGEALDVIM KDKILKIKFY TLARSASTLI ACRVTPKQKS LLVKENSAFN PRGTSLAIGD 1450 1460 1470 1480 1490 1500 GANDVGMILM ANVGVGIAGK EGLQAARSSD FTISEFKYLK KLLFVHGRES LRRNSFLVYF 1510 1520 1530 1540 1550 1560 CIFRNVSFCL CSMILIFWTG YSAIDAWNPW TKQIINIAFT SLPVIFFVAL DKQLPHNILL 1570 1580 1590 1600 1610 1620 NNPLLYETSP STLWPFYSNR KMEFYTNKVK GCYKSFYKFC FFPIRYIPYI QRYTEKIKSW 1630 1640 1650 1660 1670 1680 IGKRSKPEKY RTYGTHYLFV YLLFAIWLAT VETVIMLHFS TGQAYSSSLK DNHHVDIDFN 1690 1700 1710 1720 1730 1740 TFSQILYTHH VIAVNIVVVL MTNTWFFISH VVLWIELIAT FFFWFIISNT KFFLDIIGAD 1750 1760 1770 1780 1790 1800 ELHGTFEKAH SSGNYYASLI ISLYISILPL IILMTYQFIK KPTMEQIVLE QLKLGKFEGL 1810 1820 1830 1840 1850 1860 RKHEIKKLAY IDNQKSSNEF THKGFAFAVE AKEAFWGLVQ KAIYKIKMPL VKDETANIKH KRKS

References

[1]	"Genome sequence of the human malaria parasite Plasmodium falciparum." Gardner M.J., Hall N., Fung E., White O., Berriman M., Hyman R.W., Carlton J.M., Pain A., Nelson K.E., Bowman S., Paulsen I.T., James K.D., Eisen J.A., Rutherford K.M., Salzberg S.L., Craig A., Kyes S., Chan M.-S. , Nene V., Shallom S.J., Suh B., Peterson J., Angiuoli S., Pertea M., Allen J., Selengut J., Haft D., Mather M.W., Vaidya A.B., Martin D.M.A., Fairlamb A.H., Fraunholz M.J., Roos D.S., Ralph S.A., McFadden G.I., Cummings L.M., Subramanian G.M., Mungall C., Venter J.C., Carucci D.J., Hoffman S.L., Newbold C., Davis R.W., Fraser C.M., Barrell B.G. Nature 419:498-511(2002) [PubMed: 12368864] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Isolate 3D7.
[2]	"Sequence of Plasmodium falciparum chromosomes 1, 3-9 and 13." Hall N., Pain A., Berriman M., Churcher C.M., Harris B., Harris D., Mungall K.L., Bowman S., Atkin R., Baker S., Barron A., Brooks K., Buckee C.O., Burrows C., Cherevach I., Chillingworth C., Chillingworth T., Christodoulou Z. , Clark L., Clark R., Corton C., Cronin A., Davies R.M., Davis P., Dear P., Dearden F., Doggett J., Feltwell T., Goble A., Goodhead I., Gwilliam R., Hamlin N., Hance Z., Harper D., Hauser H., Hornsby T., Holroyd S., Horrocks P., Humphray S., Jagels K., James K.D., Johnson D., Kerhornou A., Knights A., Konfortov B., Kyes S., Larke N., Lawson D., Lennard N., Line A., Maddison M., Mclean J., Mooney P., Moule S., Murphy L., Oliver K., Ormond D., Price C., Quail M.A., Rabbinowitsch E., Rajandream M.A., Rutter S., Rutherford K.M., Sanders M., Simmonds M., Seeger K., Sharp S., Smith R., Squares R., Squares S., Stevens K., Taylor K., Tivey A., Unwin L., Whitehead S., Woodward J.R., Sulston J.E., Craig A., Newbold C., Barrell B.G. Nature 419:527-531(2002) [PubMed: 12368867] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Isolate 3D7.
[3]	"The complete nucleotide sequence of chromosome 3 of Plasmodium falciparum." Bowman S., Lawson D., Basham D., Brown D., Chillingworth T., Churcher C.M., Craig A., Davies R.M., Devlin K., Feltwell T., Gentles S., Gwilliam R., Hamlin N., Harris D., Holroyd S., Hornsby T., Horrocks P., Jagels K. , Jassal B., Kyes S., McLean J., Moule S., Mungall K.L., Murphy L., Oliver K., Quail M.A., Rajandream M.A., Rutter S., Skelton J., Squares R., Squares S., Sulston J.E., Whitehead S., Woodward J.R., Newbold C., Barrell B.G. Nature 400:532-538(1999) [PubMed: 10448855] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Isolate 3D7.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL844502 Genomic DNA. Translation: CAB11124.1.
PIR	T18485.
RefSeq	XP_001351260.1. XM_001351224.1.
3D structure databases
ProteinModelPortal	O77368.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblProtists	PFC0840w:mRNA; PFC0840w:pep; PFC0840w.
GeneID	814504.
GenomeReviews	Gene locus PfATPase7 in contig AL844502_GR.
KEGG	pfa:PFC0840w.
NMPDR	fig|36329.1.peg.182.
Organism-specific databases
EuPathDB	EupathDB:PFC0840w.
Phylogenomic databases
GeneTree	EPrGT00050000000234.
HOGENOM	HBG630803.
ProtClustDB	CLSZ2433495.
Family and domain databases
InterPro	IPR023306. ATPase_cation_domN. IPR008250. ATPase_P-typ_ATPase-assoc-dom. IPR023300. ATPase_P-typ_cyto_domA. IPR023299. ATPase_P-typ_cyto_domN. IPR001757. ATPase_P-typ_ion-transptr. IPR018303. ATPase_P-typ_P_site. IPR023214. HAD-like_dom. [Graphical view]
Gene3D	G3DSA:2.70.150.10. ATPase_P-typ_cyto_domA. 2 hits. G3DSA:3.40.1110.10. ATPase_P-typ_cyto_domN. 4 hits. G3DSA:3.40.50.1000. HAD-like_dom. 3 hits.
KO	K01552.
Pfam	PF00122. E1-E2_ATPase. 2 hits. [Graphical view]
SUPFAM	SSF81660. ATPase_cation_domN. 1 hit. SSF56784. HAD-like_dom. 1 hit.
TIGRFAMs	TIGR01494. ATPase_P-type. 1 hit.
PROSITE	PS00154. ATPASE_E1_E2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

O77368_PLAF7

Accession

Primary (citable) accession number: O77368

Entry history

Integrated into UniProtKB/TrEMBL:	November 1, 1998
Last sequence update:	November 1, 1998
Last modified:	January 25, 2012
This is version 75 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)