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Protein

Putative conotoxin

Gene
N/A
Organism
Conus imperialis (Imperial cone)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Acts as a neurotoxin.By similarity

Miscellaneous

The mature peptide contains only 1 cysteine residue.Curated

GO - Molecular functioni

Keywordsi

Molecular functionNeurotoxin, Toxin

Names & Taxonomyi

Protein namesi
Recommended name:
Putative conotoxin
OrganismiConus imperialis (Imperial cone)
Taxonomic identifieri35631 [NCBI]
Taxonomic lineageiEukaryotaMetazoaLophotrochozoaMolluscaGastropodaCaenogastropodaHypsogastropodaNeogastropodaConoideaConidaeConus

Organism-specific databases

ConoServeri77. putative peptide precursor.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 25Sequence analysisAdd BLAST25
PropeptideiPRO_000003512226 – 47Sequence analysisAdd BLAST22
PeptideiPRO_000003512350 – 59Putative conotoxin10

Keywords - PTMi

Cleavage on pair of basic residues

Expressioni

Tissue specificityi

Expressed by the venom duct.Curated

Structurei

3D structure databases

ProteinModelPortaliO77256.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the conotoxin A superfamily.Curated

Keywords - Domaini

Signal

Family and domain databases

InterProiView protein in InterPro
IPR009958. Conotoxin_a-typ.
PfamiView protein in Pfam
PF07365. Toxin_8. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

O77256-1 [UniParc]FASTAAdd to basket

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        10         20         30         40         50
MGMRMMFTVF LLVVLATTVV PITLASATDG RNAAANARVS PVISKSSKKW

CHPNPYTVG
Length:59
Mass (Da):6,309
Last modified:November 1, 1998 - v1
Checksum:i05A7813D2C3E9F67
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ011793 mRNA. Translation: CAA09785.1.

Similar proteinsi

Entry informationi

Entry nameiCAY1_CONIM
AccessioniPrimary (citable) accession number: O77256
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 13, 2002
Last sequence update: November 1, 1998
Last modified: November 22, 2017
This is version 43 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programAnimal Toxin Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families