Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Myosin-IA

Gene

MIA

Organism
Acanthamoeba castellanii (Amoeba)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Motor protein, MyosinSAAS annotation

Keywords - Ligandi

ATP-bindingSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Myosin-IAImported
Gene namesi
Name:MIAImported
OrganismiAcanthamoeba castellanii (Amoeba)Imported
Taxonomic identifieri5755 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaDiscoseaLongamoebiaCentramoebidaAcanthamoebidaeAcanthamoeba

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Structurei

3D structure databases

ProteinModelPortaliO77202.
SMRiO77202. Positions 1163-1215.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini11 – 687677Myosin motorInterPro annotationAdd
BLAST
Domaini763 – 961199TH1 (class I myosin tail homology)InterPro annotationAdd
BLAST
Domaini1159 – 121557SH3InterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.SAAS annotation
Contains TH1 (class I myosin tail homology) domain.SAAS annotation
Contains myosin motor domain.SAAS annotation

Keywords - Domaini

SH3 domainSAAS annotation

Family and domain databases

InterProiIPR001609. Myosin_head_motor_dom.
IPR010926. Myosin_TH1.
IPR027417. P-loop_NTPase.
IPR001452. SH3_domain.
[Graphical view]
PfamiPF00063. Myosin_head. 1 hit.
PF06017. Myosin_TH1. 1 hit.
PF14604. SH3_9. 1 hit.
[Graphical view]
PRINTSiPR00193. MYOSINHEAVY.
PR00452. SH3DOMAIN.
SMARTiSM00242. MYSc. 1 hit.
SM00326. SH3. 1 hit.
[Graphical view]
SUPFAMiSSF50044. SSF50044. 1 hit.
SSF52540. SSF52540. 1 hit.
PROSITEiPS51456. MYOSIN_MOTOR. 1 hit.
PS50002. SH3. 1 hit.
PS51757. TH1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O77202-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAEWVNVMKQ EGLDDMTLLA KVSNDEICNN VKLRYDKDII YTSIGFVLIS
60 70 80 90 100
MNPYKDLPIY TEGVLEDYIG KSRLELPPHI FAIGEGAYRS MKNDKENQCI
110 120 130 140 150
IISGESGAGK TEAAKKIMMY ISHASSSKGD VERVKHIIYE TNPVLEAFGN
160 170 180 190 200
AKTLRNDNSS RFGKYFEIQF NAEGDPIGGI ISNFLLEKSR VVDQSKGERN
210 220 230 240 250
FHIFYQFCRG ANAQQKTAYG LHEPESFAYL NKGECTSVST IDDVKWWQET
260 270 280 290 300
QEALNVIGIS PQEQDSLFKV IASILWLGNV DFHEQGDKST IRDQDVLDFV
310 320 330 340 350
ASLLGIPTEF LANALTIRQI ETKHGARAGT TYALNLNKMQ AIGSRDALAK
360 370 380 390 400
AMYARIFDWL IARINQALVT TQKVTASIGV LDIYGFEVFQ KNGFEQFCIN
410 420 430 440 450
YVNEKLQQVF IELTLKLEQE EYVKEGIQWT PIQFFNNKIV CDLIEATRPP
460 470 480 490 500
GVFCVLDDVC KTVTKVDPDN RFADRLSACN GNEHFKHRGK AFTIKHYAGD
510 520 530 540 550
VTYEVGGMPE KNKDTLFKDL LETIKLAENT FLSQTLFPEE VDRDSKKAPT
560 570 580 590 600
TFGYKIKSQA NDLIATLMKA TPHYVRCIKP NDDKKSNHFV KDRVMHQIVY
610 620 630 640 650
LGLLDNLKVR RAGFAYRAPF QKFMDRYFLI SKQCSYAAQR IWKGDDISGS
660 670 680 690 700
KAILADNYIG NDQYQIGKTK IFIRHPETLY HLEDLRENYW HNMVNRIKNA
710 720 730 740 750
YYTYKNFHGE CVSRIKLAFK VWKAYREEML VIIQRAYREF KNLSPFYDFR
760 770 780 790 800
MDNEKVMHGN KQRNRLSMAS VRKFYGDYLD MRYQRALLDA MGPGAGNEKV
810 820 830 840 850
IFSFKCKTVV HPGFLGSPKL SPRYLCLTEQ YLYLVALVVK KKVATHVLDK
860 870 880 890 900
KVPINFIESV SLSPLYDNYL IIHCPQDADL VLELDYKTEL VAWLRSKKPV
910 920 930 940 950
NVRFSAEILY MKKKGKEQKL QFTQDLDQFR VKLKADPAAT TFYKKHHVYT
960 970 980 990 1000
VTGLPPNSVP REFLKQAGVI PHQQTPAPQP SAPQRGRGPA PPRGGRGAGR
1010 1020 1030 1040 1050
ALPMGGGDEA PLPPVPTGPS GGPGPAGPGR GMPAGPGRGA PGPGRGGPGG
1060 1070 1080 1090 1100
PPGPAGPGRG APGPGRGAPG PSRGGPGGPP PGGRGMPPPG GRGGPGGPGP
1110 1120 1130 1140 1150
AGPGGRGMPA PGGGRGGPGG PGPAGRGGPG PAGRGMPPPG AGRGGPAPAA
1160 1170 1180 1190 1200
AQPALPAVPT VGRCRALYDY GAQEADELTL REGDVIDVIQ KSGEWWEGTL
1210
NGKTGVFPAN YVEDI
Length:1,215
Mass (Da):134,104
Last modified:November 1, 1998 - v1
Checksum:iFEFBFCC2EF936C72
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF085185 Genomic DNA. Translation: AAC35357.1.
PIRiT32734.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF085185 Genomic DNA. Translation: AAC35357.1.
PIRiT32734.

3D structure databases

ProteinModelPortaliO77202.
SMRiO77202. Positions 1163-1215.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

InterProiIPR001609. Myosin_head_motor_dom.
IPR010926. Myosin_TH1.
IPR027417. P-loop_NTPase.
IPR001452. SH3_domain.
[Graphical view]
PfamiPF00063. Myosin_head. 1 hit.
PF06017. Myosin_TH1. 1 hit.
PF14604. SH3_9. 1 hit.
[Graphical view]
PRINTSiPR00193. MYOSINHEAVY.
PR00452. SH3DOMAIN.
SMARTiSM00242. MYSc. 1 hit.
SM00326. SH3. 1 hit.
[Graphical view]
SUPFAMiSSF50044. SSF50044. 1 hit.
SSF52540. SSF52540. 1 hit.
PROSITEiPS51456. MYOSIN_MOTOR. 1 hit.
PS50002. SH3. 1 hit.
PS51757. TH1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Hydrodynamic and ligand binding properties of Acanthamoeba Myosin-IA GPA/SH3 domain."
    Lee W.-L., Ostap E.M., Zot H.G., Pollard T.D.
    Submitted (AUG-1998) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: NeffImported.

Entry informationi

Entry nameiO77202_ACACA
AccessioniPrimary (citable) accession number: O77202
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1998
Last sequence update: November 1, 1998
Last modified: May 11, 2016
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.