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Protein
Submitted name:

Myosin-IA

Gene

MIA

Organism
Acanthamoeba castellanii (Amoeba)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi104 – 111ATPPROSITE-ProRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionActin-bindingPROSITE-ProRule annotationSAAS annotation, Motor protein, MyosinPROSITE-ProRule annotationSAAS annotation
LigandATP-bindingSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Myosin-IAImported
Gene namesi
Name:MIAImported
OrganismiAcanthamoeba castellanii (Amoeba)Imported
Taxonomic identifieri5755 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaDiscoseaLongamoebiaCentramoebidaAcanthamoebidaeAcanthamoeba

Subcellular locationi

GO - Cellular componenti

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliO77202
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini11 – 687Myosin motorInterPro annotationAdd BLAST677
Domaini763 – 961TH1InterPro annotationAdd BLAST199
Domaini1159 – 1215SH3InterPro annotationAdd BLAST57

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni560 – 582Actin-bindingPROSITE-ProRule annotationAdd BLAST23

Sequence similaritiesi

Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.PROSITE-ProRule annotationSAAS annotation

Keywords - Domaini

SH3 domainPROSITE-ProRule annotationSAAS annotation

Family and domain databases

CDDicd01378 MYSc_Myo1, 1 hit
Gene3Di3.40.850.10, 3 hits
InterProiView protein in InterPro
IPR036961 Kinesin_motor_dom_sf
IPR001609 Myosin_head_motor_dom
IPR010926 Myosin_TH1
IPR036072 MYSc_Myo1
IPR027417 P-loop_NTPase
IPR036028 SH3-like_dom_sf
IPR001452 SH3_domain
PfamiView protein in Pfam
PF00063 Myosin_head, 1 hit
PF06017 Myosin_TH1, 1 hit
PF14604 SH3_9, 1 hit
PRINTSiPR00193 MYOSINHEAVY
PR00452 SH3DOMAIN
SMARTiView protein in SMART
SM00242 MYSc, 1 hit
SM00326 SH3, 1 hit
SUPFAMiSSF50044 SSF50044, 1 hit
SSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS51456 MYOSIN_MOTOR, 1 hit
PS50002 SH3, 1 hit
PS51757 TH1, 1 hit

Sequencei

Sequence statusi: Complete.

O77202-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAEWVNVMKQ EGLDDMTLLA KVSNDEICNN VKLRYDKDII YTSIGFVLIS
60 70 80 90 100
MNPYKDLPIY TEGVLEDYIG KSRLELPPHI FAIGEGAYRS MKNDKENQCI
110 120 130 140 150
IISGESGAGK TEAAKKIMMY ISHASSSKGD VERVKHIIYE TNPVLEAFGN
160 170 180 190 200
AKTLRNDNSS RFGKYFEIQF NAEGDPIGGI ISNFLLEKSR VVDQSKGERN
210 220 230 240 250
FHIFYQFCRG ANAQQKTAYG LHEPESFAYL NKGECTSVST IDDVKWWQET
260 270 280 290 300
QEALNVIGIS PQEQDSLFKV IASILWLGNV DFHEQGDKST IRDQDVLDFV
310 320 330 340 350
ASLLGIPTEF LANALTIRQI ETKHGARAGT TYALNLNKMQ AIGSRDALAK
360 370 380 390 400
AMYARIFDWL IARINQALVT TQKVTASIGV LDIYGFEVFQ KNGFEQFCIN
410 420 430 440 450
YVNEKLQQVF IELTLKLEQE EYVKEGIQWT PIQFFNNKIV CDLIEATRPP
460 470 480 490 500
GVFCVLDDVC KTVTKVDPDN RFADRLSACN GNEHFKHRGK AFTIKHYAGD
510 520 530 540 550
VTYEVGGMPE KNKDTLFKDL LETIKLAENT FLSQTLFPEE VDRDSKKAPT
560 570 580 590 600
TFGYKIKSQA NDLIATLMKA TPHYVRCIKP NDDKKSNHFV KDRVMHQIVY
610 620 630 640 650
LGLLDNLKVR RAGFAYRAPF QKFMDRYFLI SKQCSYAAQR IWKGDDISGS
660 670 680 690 700
KAILADNYIG NDQYQIGKTK IFIRHPETLY HLEDLRENYW HNMVNRIKNA
710 720 730 740 750
YYTYKNFHGE CVSRIKLAFK VWKAYREEML VIIQRAYREF KNLSPFYDFR
760 770 780 790 800
MDNEKVMHGN KQRNRLSMAS VRKFYGDYLD MRYQRALLDA MGPGAGNEKV
810 820 830 840 850
IFSFKCKTVV HPGFLGSPKL SPRYLCLTEQ YLYLVALVVK KKVATHVLDK
860 870 880 890 900
KVPINFIESV SLSPLYDNYL IIHCPQDADL VLELDYKTEL VAWLRSKKPV
910 920 930 940 950
NVRFSAEILY MKKKGKEQKL QFTQDLDQFR VKLKADPAAT TFYKKHHVYT
960 970 980 990 1000
VTGLPPNSVP REFLKQAGVI PHQQTPAPQP SAPQRGRGPA PPRGGRGAGR
1010 1020 1030 1040 1050
ALPMGGGDEA PLPPVPTGPS GGPGPAGPGR GMPAGPGRGA PGPGRGGPGG
1060 1070 1080 1090 1100
PPGPAGPGRG APGPGRGAPG PSRGGPGGPP PGGRGMPPPG GRGGPGGPGP
1110 1120 1130 1140 1150
AGPGGRGMPA PGGGRGGPGG PGPAGRGGPG PAGRGMPPPG AGRGGPAPAA
1160 1170 1180 1190 1200
AQPALPAVPT VGRCRALYDY GAQEADELTL REGDVIDVIQ KSGEWWEGTL
1210
NGKTGVFPAN YVEDI
Length:1,215
Mass (Da):134,104
Last modified:November 1, 1998 - v1
Checksum:iFEFBFCC2EF936C72
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF085185 Genomic DNA Translation: AAC35357.1
PIRiT32734

Similar proteinsi

Entry informationi

Entry nameiO77202_ACACA
AccessioniPrimary (citable) accession number: O77202
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1998
Last sequence update: November 1, 1998
Last modified: April 25, 2018
This is version 93 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health