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Protein
Submitted name:

70 kDa heat shock protein Hsp70-Bip

Gene

BiP

Organism
Entamoeba histolytica
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Biological processi

Stress responseImported

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
70 kDa heat shock protein Hsp70-BipImported
Gene namesi
Name:BiPImported
OrganismiEntamoeba histolyticaImported
Taxonomic identifieri5759 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaArchamoebaeEntamoebidaeEntamoeba

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1616Sequence analysisAdd
BLAST
Chaini17 – 661645Sequence analysisPRO_5004159851Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi5759.rna_EHI_199590-1.

Structurei

3D structure databases

ProteinModelPortaliO77164.
SMRiO77164. Positions 27-569.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili277 – 30428Sequence analysisAdd
BLAST
Coiled coili534 – 56128Sequence analysisAdd
BLAST

Sequence similaritiesi

Belongs to the heat shock protein 70 family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis, SignalSequence analysis

Phylogenomic databases

eggNOGiKOG0100. Eukaryota.
COG0443. LUCA.

Family and domain databases

Gene3Di1.20.1270.10. 1 hit.
2.60.34.10. 1 hit.
InterProiIPR018181. Heat_shock_70_CS.
IPR029048. HSP70_C.
IPR029047. HSP70_peptide-bd.
IPR013126. Hsp_70_fam.
[Graphical view]
PfamiPF00012. HSP70. 1 hit.
[Graphical view]
PRINTSiPR00301. HEATSHOCK70.
SUPFAMiSSF100920. SSF100920. 1 hit.
SSF100934. SSF100934. 1 hit.
PROSITEiPS00297. HSP70_1. 1 hit.
PS00329. HSP70_2. 1 hit.
PS01036. HSP70_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O77164-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLTFLFTLLF CITVFSEDTK QEDKVDGRVI GIDLGTTFSA VGIYNGEGKG
60 70 80 90 100
VEILVNDQGN RITPSVVAFT DTEILVGEAA KNQIAHNPVN TIFDIKRLIG
110 120 130 140 150
RTFDDKEVQR DLKLFPYKII NKNNKPFIEV KYKGERKEYS PEEISAMVIK
160 170 180 190 200
KMADTASTYL GKEVKHAVIT VPAYFNDAQR QATKDAGKIA GLNVLRILNE
210 220 230 240 250
PTAAVMAYGL NKVGGEKNIL VFDLGGGTFD VSLLNIEDNV FDVISTSGNT
260 270 280 290 300
HLGGSDFDQK VTEYLVDVFK RKYGKDLRND KRAITRLRRE AERAKRALSV
310 320 330 340 350
QQQDRIEIEN LADGIDFSFT LTRAKFEELN LELFKSTIAP VKKVLEDSGM
360 370 380 390 400
SKGSIHEVVL VGGSTRIPKV QQLLKEFFNG KEPSRGINPD EAVAYGAAVQ
410 420 430 440 450
GGVLSNIKGT EDIVLLDTTP LTLGIETVGG VMTSLIKRNT HIPISKSQTF
460 470 480 490 500
STYQDNQPSV TIQVFEGERT MTKDNHFLGK FDLDGIQPAP RGVPQIEVTF
510 520 530 540 550
EVDVNGILTV SAEDKKSGKS EKITITSEKG RLTEEEIERM IKEAEERAED
560 570 580 590 600
DKKLKEQVEA KNQLENYAYQ IKNTVNDNEK LGGKIEEGDK KVLLDAVQDV
610 620 630 640 650
TSFLENNATP TKEECDDKYK QLEQIAQPIL AKYGGGAQQQ APGYDNNQQY
660
GNYEEYEKDE L
Length:661
Mass (Da):73,546
Last modified:November 1, 1998 - v1
Checksum:i8FC1384158DFD922
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF082519 Genomic DNA. Translation: AAC64065.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF082519 Genomic DNA. Translation: AAC64065.1.

3D structure databases

ProteinModelPortaliO77164.
SMRiO77164. Positions 27-569.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi5759.rna_EHI_199590-1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiKOG0100. Eukaryota.
COG0443. LUCA.

Family and domain databases

Gene3Di1.20.1270.10. 1 hit.
2.60.34.10. 1 hit.
InterProiIPR018181. Heat_shock_70_CS.
IPR029048. HSP70_C.
IPR029047. HSP70_peptide-bd.
IPR013126. Hsp_70_fam.
[Graphical view]
PfamiPF00012. HSP70. 1 hit.
[Graphical view]
PRINTSiPR00301. HEATSHOCK70.
SUPFAMiSSF100920. SSF100920. 1 hit.
SSF100934. SSF100934. 1 hit.
PROSITEiPS00297. HSP70_1. 1 hit.
PS00329. HSP70_2. 1 hit.
PS01036. HSP70_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Chitinase secretion by encysting Entamoeba invadens and transfected Entamoeba histolytica."
    Samuelson J., Field J.
    Submitted (AUG-1998) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: HM-1:IMSSImported.

Entry informationi

Entry nameiO77164_ENTHI
AccessioniPrimary (citable) accession number: O77164
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1998
Last sequence update: November 1, 1998
Last modified: March 16, 2016
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.