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Protein
Submitted name:

Nuclear receptor 1

Gene

NR1

Organism
Ciona intestinalis (Transparent sea squirt) (Ascidia intestinalis)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

ReceptorUniRule annotationImported

Keywords - Biological processi

Transcription, Transcription regulationUniRule annotationSAAS annotation

Keywords - Ligandi

DNA-bindingUniRule annotationSAAS annotation, Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Nuclear receptor 1Imported
Gene namesi
Name:NR1Imported
OrganismiCiona intestinalis (Transparent sea squirt) (Ascidia intestinalis)Imported
Taxonomic identifieri7719 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataTunicataAscidiaceaEnterogonaPhlebobranchiaCionidaeCiona

Subcellular locationi

  • Nucleus UniRule annotationSAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

NucleusUniRule annotationSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi7719.ENSCINP00000031213.

Structurei

3D structure databases

ProteinModelPortaliO77154.
SMRiO77154. Positions 41-129.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini41 – 11878Nuclear receptor DNA-bindingInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the nuclear hormone receptor family.UniRule annotationSAAS annotation
Contains 1 Nuclear receptor DNA-binding domain.UniRule annotation
Contains nuclear receptor DNA-binding domain.SAAS annotation

Keywords - Domaini

Zinc-fingerUniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG3575. Eukaryota.
ENOG410XRZC. LUCA.
HOVERGENiHBG053190.
KOiK08362.

Family and domain databases

Gene3Di1.10.565.10. 1 hit.
3.30.50.10. 1 hit.
InterProiIPR000536. Nucl_hrmn_rcpt_lig-bd.
IPR001723. Nuclear_hrmn_rcpt.
IPR001728. ThyrH_rcpt.
IPR001628. Znf_hrmn_rcpt.
IPR013088. Znf_NHR/GATA.
[Graphical view]
PfamiPF00104. Hormone_recep. 1 hit.
PF00105. zf-C4. 1 hit.
[Graphical view]
PRINTSiPR00398. STRDHORMONER.
PR00047. STROIDFINGER.
PR00546. THYROIDHORMR.
SMARTiSM00430. HOLI. 1 hit.
SM00399. ZnF_C4. 1 hit.
[Graphical view]
SUPFAMiSSF48508. SSF48508. 1 hit.
PROSITEiPS00031. NUCLEAR_REC_DBD_1. 1 hit.
PS51030. NUCLEAR_REC_DBD_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O77154-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MERNQIIPNS IDCFPRHAMG RGNKDKRKNM KGYIPSYLDG NEECVVCGDK
60 70 80 90 100
ATGYHYRCIT CEGCKGFFRR TVQKDLQKTY QCKQRGKCQV NKVSRNQCQM
110 120 130 140 150
CRYEKCIATG MATDLVLNED KRIAKRKLIE RNRQLRRHKD ISHVMGTWKV
160 170 180 190 200
GRGSDDDNHV ISAVVQAHND VINDDDFEET SRSPTHGEQF SSALTNAVTR
210 220 230 240 250
VVEFAKRLPF FTGKASTDDQ VAMLKGCCME VIVLNCVASY DRARCTLKLF
260 270 280 290 300
SKVIITREKL RRTRFDHFAD DLFRTAEEMS ILQLTETEIA MLKAIIVFAA
310 320 330 340 350
DRPRIQHIDE IRNIQNSLLQ SLRYYVMDKA QHEYAVWSML LIKMADIRRI
360 370 380 390 400
SNGFAASLMD MKLNNPEELV VLFAKDRSGT SDDHTPLQDA RMDTTKTSAS
410 420 430 440 450
QKLCQKGGNK ENRMDNSKQV STSVKKESDS WPPTYKRDEP FMSNRALLLQ
460 470 480 490 500
HYGVWSCFPK PSYDLPNPSV PKPSGFQPLQ LPHAALSGHV GKTLGRNNFI
510 520 530 540 550
LPTALHPSLN TVKHLDMFRV MPVDSGEFIP SINPPAYIAN SKTNVSPQTR
560 570 580
WLLKERFTQE KGTHISDKNV HANQNATEEA INLSLKL
Length:587
Mass (Da):66,875
Last modified:November 1, 1998 - v1
Checksum:iAE5F76E67FA1E172
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF077403 mRNA. Translation: AAC42665.1.
RefSeqiNP_001027658.1. NM_001032486.1.
UniGeneiCin.23009.

Genome annotation databases

GeneIDi445665.
KEGGicin:445665.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF077403 mRNA. Translation: AAC42665.1.
RefSeqiNP_001027658.1. NM_001032486.1.
UniGeneiCin.23009.

3D structure databases

ProteinModelPortaliO77154.
SMRiO77154. Positions 41-129.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7719.ENSCINP00000031213.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi445665.
KEGGicin:445665.

Organism-specific databases

CTDi445665.

Phylogenomic databases

eggNOGiKOG3575. Eukaryota.
ENOG410XRZC. LUCA.
HOVERGENiHBG053190.
KOiK08362.

Family and domain databases

Gene3Di1.10.565.10. 1 hit.
3.30.50.10. 1 hit.
InterProiIPR000536. Nucl_hrmn_rcpt_lig-bd.
IPR001723. Nuclear_hrmn_rcpt.
IPR001728. ThyrH_rcpt.
IPR001628. Znf_hrmn_rcpt.
IPR013088. Znf_NHR/GATA.
[Graphical view]
PfamiPF00104. Hormone_recep. 1 hit.
PF00105. zf-C4. 1 hit.
[Graphical view]
PRINTSiPR00398. STRDHORMONER.
PR00047. STROIDFINGER.
PR00546. THYROIDHORMR.
SMARTiSM00430. HOLI. 1 hit.
SM00399. ZnF_C4. 1 hit.
[Graphical view]
SUPFAMiSSF48508. SSF48508. 1 hit.
PROSITEiPS00031. NUCLEAR_REC_DBD_1. 1 hit.
PS51030. NUCLEAR_REC_DBD_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiO77154_CIOIN
AccessioniPrimary (citable) accession number: O77154
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1998
Last sequence update: November 1, 1998
Last modified: September 7, 2016
This is version 103 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.