Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Major royal jelly protein 2

Gene

MRJP2

Organism
Apis mellifera (Honeybee)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

May play an important role in honeybee nutrition. It is found in the royal jelly which is the food of the queen honey bee larva. The royal jelly determines the development of the young larvae and is responsible for the high reproductive ability of the honeybee queen.

Names & Taxonomyi

Protein namesi
Recommended name:
Major royal jelly protein 2
Short name:
MRJP-2
Alternative name(s):
Bee-milk protein
Gene namesi
Name:MRJP2
OrganismiApis mellifera (Honeybee)
Taxonomic identifieri7460 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaHymenopteraApocritaAculeataApoideaApidaeApis
Proteomesi
  • UP000005203 Componenti: Unplaced

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Secreted

Pathology & Biotechi

Protein family/group databases

Allergomei7628. Api m Apalbumin 2.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 17171 PublicationAdd
BLAST
Chaini18 – 452435Major royal jelly protein 2PRO_0000031044Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi145 – 1451N-linked (GlcNAc...)Sequence analysis
Glycosylationi178 – 1781N-linked (GlcNAc...)Sequence analysis

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiO77061.
PRIDEiO77061.

Expressioni

Tissue specificityi

Found in the hypopharyngeal glands.

Developmental stagei

Produced in the cephalic glands of the nurse honeybee.

Structurei

3D structure databases

ProteinModelPortaliO77061.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the major royal jelly protein family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG410KG2T. Eukaryota.
ENOG4110SQU. LUCA.
InParanoidiO77061.
PhylomeDBiO77061.

Family and domain databases

Gene3Di2.120.10.30. 1 hit.
InterProiIPR011042. 6-blade_b-propeller_TolB-like.
IPR017996. Royal_jelly/protein_yellow.
[Graphical view]
PANTHERiPTHR10009. PTHR10009. 1 hit.
PfamiPF03022. MRJP. 1 hit.
[Graphical view]
PRINTSiPR01366. ROYALJELLY.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

O77061-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTRWLFMVAC LGIACQGAIV RENSPRNLEK SLNVIHEWKY FDYDFGSEER
60 70 80 90 100
RQAAIQSGEY DHTKNYPFDV DQWRDKTFVT ILRYDGVPST LNVISGKTGK
110 120 130 140 150
GGRLLKPYPD WSFAEFKDCS KIVSAFKIAI DKFDRLWVLD SGLVNRTVPV
160 170 180 190 200
CAPKLHVFDL KTSNHLKQIE IPHDIAVNAT TGKGGLVSLA VQAIDLANTL
210 220 230 240 250
VYMADHKGDA LIVYQNADDS FHRLTSNTFD YDPRYAKMTI DGESFTLKNG
260 270 280 290 300
ICGMALSPVT NNLYYSPLAS HGLYYVNTAP FMKSQFGENN VQYQGSEDIL
310 320 330 340 350
NTQSLAKAVS KNGVLFVGLV GNSAVGCWNE HQSLQRQNLE MVAQNDRTLQ
360 370 380 390 400
MIAGMKIKEE LPHFVGSNKP VKDEYMLVLS NRMQKIVNDD FNFDDVNFRI
410 420 430 440 450
LGANVKELIR NTHCVNNNQN DNIQNTNNQN DNNQKNNKKN ANNQKNNNQN

DN
Length:452
Mass (Da):51,074
Last modified:November 1, 1998 - v1
Checksum:i25E5B621288FE189
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF000632 mRNA. Translation: AAC61894.1.
RefSeqiNP_001011580.1. NM_001011580.1.
UniGeneiAme.209.

Genome annotation databases

GeneIDi406091.
KEGGiame:406091.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF000632 mRNA. Translation: AAC61894.1.
RefSeqiNP_001011580.1. NM_001011580.1.
UniGeneiAme.209.

3D structure databases

ProteinModelPortaliO77061.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

Allergomei7628. Api m Apalbumin 2.

Proteomic databases

PaxDbiO77061.
PRIDEiO77061.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi406091.
KEGGiame:406091.

Organism-specific databases

CTDi406091.

Phylogenomic databases

eggNOGiENOG410KG2T. Eukaryota.
ENOG4110SQU. LUCA.
InParanoidiO77061.
PhylomeDBiO77061.

Family and domain databases

Gene3Di2.120.10.30. 1 hit.
InterProiIPR011042. 6-blade_b-propeller_TolB-like.
IPR017996. Royal_jelly/protein_yellow.
[Graphical view]
PANTHERiPTHR10009. PTHR10009. 1 hit.
PfamiPF03022. MRJP. 1 hit.
[Graphical view]
PRINTSiPR01366. ROYALJELLY.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [MRNA], PROTEIN SEQUENCE OF 18-30.
    Tissue: Head.

Entry informationi

Entry nameiMRJP2_APIME
AccessioniPrimary (citable) accession number: O77061
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 23, 2002
Last sequence update: November 1, 1998
Last modified: July 6, 2016
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.