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Protein

Carboxylic ester hydrolase

Gene

ChE1

Organism
Branchiostoma floridae (Florida lancelet) (Amphioxus)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

HydrolaseUniRule annotationSAAS annotationImported

Protein family/group databases

ESTHERibrafl-ACHE1. AChE.

Names & Taxonomyi

Protein namesi
Recommended name:
Carboxylic ester hydrolaseUniRule annotation (EC:3.1.1.-UniRule annotation)
Gene namesi
Name:ChE1Imported
OrganismiBranchiostoma floridae (Florida lancelet) (Amphioxus)Imported
Taxonomic identifieri7739 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCephalochordataBranchiostomidaeBranchiostoma

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2222UniRule annotationAdd
BLAST
Chaini23 – 605583Carboxylic ester hydrolaseUniRule annotationPRO_5005142279Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi7739.JGI272035.

Structurei

3D structure databases

ProteinModelPortaliO76998.
SMRiO76998. Positions 24-559.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini24 – 549526COesteraseInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the type-B carboxylesterase/lipase family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalUniRule annotation

Phylogenomic databases

eggNOGiKOG4389. Eukaryota.
COG2272. LUCA.
HOVERGENiHBG008839.

Family and domain databases

Gene3Di3.40.50.1820. 1 hit.
InterProiIPR029058. AB_hydrolase.
IPR002018. CarbesteraseB.
IPR019826. Carboxylesterase_B_AS.
IPR019819. Carboxylesterase_B_CS.
IPR000997. Cholinesterase.
[Graphical view]
PfamiPF00135. COesterase. 1 hit.
[Graphical view]
PRINTSiPR00878. CHOLNESTRASE.
SUPFAMiSSF53474. SSF53474. 1 hit.
PROSITEiPS00122. CARBOXYLESTERASE_B_1. 1 hit.
PS00941. CARBOXYLESTERASE_B_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O76998-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASRLLLQIL PLLMLVRTSV DAATSVVQTS AGQVRGLELD VLGRKVNAFL
60 70 80 90 100
GIPFAKPPVG DLRFRAPEPA DSWTLYDATQ FPNSCVSAPD EAFPGFHGAE
110 120 130 140 150
MWNPNTPISE DCLYLNVWQP TPAPTGATVL VWIYGGGFFS GTSSLDVYDG
160 170 180 190 200
RYLARMEDVV VVSMNYRLGA LGFLYSGSEA APGNVGLLDQ HLALLWVQQN
210 220 230 240 250
VHAFGGDPAK VTIFGESAGA ASVNFHMISP MSRNLFQRAI MQSASALAPW
260 270 280 290 300
ALRPSEQARK RTKALAIDIG CSAEEEDMDA LVACLRDVPA QTILDHEWNV
310 320 330 340 350
VDLTGAHFLA DIPFPPIKDG SFLTEDPTEV YEKGTFKDID ILVGFVKNEG
360 370 380 390 400
NFWLVYGVPG FSKDTDSIID RDTFVGDIEF CHPWLNDITV EATAFEYTDW
410 420 430 440 450
LHMDQDTMYR DALDSVFGDY FFVCPTTAVG KGHVNHGRTA YVYEFAQVAS
460 470 480 490 500
NLAWPHWMGA MHGYEIEFIF GLPIDPKWNY TAEEGELARR MMRYWTNFAR
510 520 530 540 550
TGNPNKRSPD DTTDDIWRPY TEEGREYIIL DTDGTRMLNG PKSKQCAFWE
560 570 580 590 600
RYMPSLQKET DDLINDAEPC SSGGRSWRSE GVAKFSSLVA VFAVLTGHRL

QVFGH
Length:605
Mass (Da):67,300
Last modified:November 1, 1998 - v1
Checksum:iE102ED7A2DC80688
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U74380 mRNA. Translation: AAD05373.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U74380 mRNA. Translation: AAD05373.1.

3D structure databases

ProteinModelPortaliO76998.
SMRiO76998. Positions 24-559.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7739.JGI272035.

Protein family/group databases

ESTHERibrafl-ACHE1. AChE.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiKOG4389. Eukaryota.
COG2272. LUCA.
HOVERGENiHBG008839.

Family and domain databases

Gene3Di3.40.50.1820. 1 hit.
InterProiIPR029058. AB_hydrolase.
IPR002018. CarbesteraseB.
IPR019826. Carboxylesterase_B_AS.
IPR019819. Carboxylesterase_B_CS.
IPR000997. Cholinesterase.
[Graphical view]
PfamiPF00135. COesterase. 1 hit.
[Graphical view]
PRINTSiPR00878. CHOLNESTRASE.
SUPFAMiSSF53474. SSF53474. 1 hit.
PROSITEiPS00122. CARBOXYLESTERASE_B_1. 1 hit.
PS00941. CARBOXYLESTERASE_B_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiO76998_BRAFL
AccessioniPrimary (citable) accession number: O76998
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1998
Last sequence update: November 1, 1998
Last modified: May 11, 2016
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.