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Protein
Submitted name:

Carmine, isoform A

Gene

cm

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • determination of adult lifespan Source: FlyBase
  • endocytosis Source: FlyBase
  • exocytosis Source: FlyBase
  • intracellular protein transport Source: InterPro
  • intracellular transport Source: FlyBase
  • lysosome organization Source: FlyBase
  • neurogenesis Source: FlyBase
  • neurotransmitter secretion Source: FlyBase
  • Notch receptor processing Source: FlyBase
  • ommochrome biosynthetic process Source: FlyBase
  • synaptic vesicle coating Source: FlyBase
  • vesicle coating Source: FlyBase
Complete GO annotation...

Keywords - Biological processi

Protein transportSAAS annotation, Transport

Names & Taxonomyi

Protein namesi
Submitted name:
Carmine, isoform AImported
Submitted name:
Carmine, isoform BImported
Submitted name:
Clathrin-associated adaptor complex AP-3 medium chainImported
Submitted name:
LD09732pImported
Submitted name:
Mu3 subunit of clathrin-associated protein complex AP-3Imported
Gene namesi
Name:cmImported
Synonyms:mu3Imported
ORF Names:CG3035Imported, Dmel_CG3035Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome X

Organism-specific databases

FlyBaseiFBgn0000330. cm.

Subcellular locationi

GO - Cellular componenti

  • AP-3 adaptor complex Source: FlyBase
  • clathrin adaptor complex Source: InterPro
  • coated vesicle Source: FlyBase
  • synaptic vesicle Source: FlyBase
Complete GO annotation...

Expressioni

Gene expression databases

BgeeiFBgn0000330.

Interactioni

Protein-protein interaction databases

MINTiMINT-311349.
STRINGi7227.FBpp0304594.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini174 – 414MHD (mu homology)InterPro annotationAdd BLAST241

Sequence similaritiesi

Belongs to the adaptor complexes medium subunit family.SAAS annotation

Phylogenomic databases

eggNOGiKOG2740. Eukaryota.
ENOG410XT7B. LUCA.
GeneTreeiENSGT00530000062779.
HOGENOMiHOG000245870.
KOiK12398.
OMAiEDYFSEC.
OrthoDBiEOG091G088V.

Family and domain databases

InterProiIPR001392. Clathrin_mu.
IPR018240. Clathrin_mu_CS.
IPR011012. Longin-like_dom.
IPR028565. MHD.
[Graphical view]
PfamiPF00928. Adap_comp_sub. 1 hit.
[Graphical view]
PIRSFiPIRSF005992. Clathrin_mu. 1 hit.
PRINTSiPR00314. CLATHRINADPT.
SUPFAMiSSF49447. SSF49447. 1 hit.
SSF64356. SSF64356. 1 hit.
PROSITEiPS00991. CLAT_ADAPTOR_M_2. 1 hit.
PS51072. MHD. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O76928-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIHSLFIVNS GGEVFLEKHW RSVVSRSVCE YFLDAQRAAP YDVPPVIATP
60 70 80 90 100
HYYLITVQRD TVSLVAACKQ EVPPLFVIEF LHRVVDTFQD YFGDCSESVI
110 120 130 140 150
KDNYVVVYEL LDEMLDNGFP LATESNILKE LIKPPNILRT IANTVTGKSN
160 170 180 190 200
VSTTLPSGQL SAVRWRRSGV RYTNNEAYFD VIEEVDAIID KSGSTVFAEI
210 220 230 240 250
QGHIDCCIKL SGMPDLTLSF MNPRLFDDVS FHPCVRYKRW EAERLLSFIP
260 270 280 290 300
PDGNFRLMSY HISSQSVVAI PIYIRHNFSI KTGEQGRLDL TIGPRNTLGR
310 320 330 340 350
TVDKVKLELT MPRCVLNCLL TPNQGKYTFD SVTKTLSWDV GRIDVSKLPN
360 370 380 390 400
IRGSVSITPG TTNIDANPSV NVQFQISQLA VSGLKVNRLD MYGEKYKPFK
410
GVKYLTKAGK FQVRM
Length:415
Mass (Da):46,796
Last modified:November 1, 1998 - v1
Checksum:i0CD6152F4B5C2984
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF110233 mRNA. Translation: AAF14249.1.
AE014298 Genomic DNA. Translation: AAF46231.1.
AY069388 mRNA. Translation: AAL39533.1.
AE014298 Genomic DNA. Translation: AGB95147.1.
AJ009657 mRNA. Translation: CAA08768.1.
RefSeqiNP_001259302.1. NM_001272373.1.
NP_788873.1. NM_176700.3.
UniGeneiDm.230.

Genome annotation databases

EnsemblMetazoaiFBtr0071033; FBpp0070992; FBgn0000330.
FBtr0332315; FBpp0304594; FBgn0000330.
GeneIDi31647.
KEGGidme:Dmel_CG3035.
UCSCiCG3035-RA. d. melanogaster.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF110233 mRNA. Translation: AAF14249.1.
AE014298 Genomic DNA. Translation: AAF46231.1.
AY069388 mRNA. Translation: AAL39533.1.
AE014298 Genomic DNA. Translation: AGB95147.1.
AJ009657 mRNA. Translation: CAA08768.1.
RefSeqiNP_001259302.1. NM_001272373.1.
NP_788873.1. NM_176700.3.
UniGeneiDm.230.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

MINTiMINT-311349.
STRINGi7227.FBpp0304594.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0071033; FBpp0070992; FBgn0000330.
FBtr0332315; FBpp0304594; FBgn0000330.
GeneIDi31647.
KEGGidme:Dmel_CG3035.
UCSCiCG3035-RA. d. melanogaster.

Organism-specific databases

CTDi111346.
FlyBaseiFBgn0000330. cm.

Phylogenomic databases

eggNOGiKOG2740. Eukaryota.
ENOG410XT7B. LUCA.
GeneTreeiENSGT00530000062779.
HOGENOMiHOG000245870.
KOiK12398.
OMAiEDYFSEC.
OrthoDBiEOG091G088V.

Miscellaneous databases

GenomeRNAii31647.

Gene expression databases

BgeeiFBgn0000330.

Family and domain databases

InterProiIPR001392. Clathrin_mu.
IPR018240. Clathrin_mu_CS.
IPR011012. Longin-like_dom.
IPR028565. MHD.
[Graphical view]
PfamiPF00928. Adap_comp_sub. 1 hit.
[Graphical view]
PIRSFiPIRSF005992. Clathrin_mu. 1 hit.
PRINTSiPR00314. CLATHRINADPT.
SUPFAMiSSF49447. SSF49447. 1 hit.
SSF64356. SSF64356. 1 hit.
PROSITEiPS00991. CLAT_ADAPTOR_M_2. 1 hit.
PS51072. MHD. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiO76928_DROME
AccessioniPrimary (citable) accession number: O76928
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1998
Last sequence update: November 1, 1998
Last modified: November 30, 2016
This is version 143 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.