Unreviewed, UniProtKB/TrEMBL O76922 (O76922_DROME)

Names and origin

Protein names

Submitted name:
    Aubergine, isoform A EMBL AAF53046.1
Submitted name:
    AUBERGINE EMBL CAA64320.1
    Sting EMBL AAD38655.1

Gene names

Name:	aub EMBL AAF53046.1 FlyBase FBgn0000146
Synonyms:	aubergine EMBL CAA64320.1, sting EMBL AAD38655.1
ORF Names:	CG6137 FlyBase FBgn0000146, Dmel_CG6137 EMBL AAF53046.1

Organism

Drosophila melanogaster (Fruit fly) [Complete proteome]

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	866 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

Ontologies

Keywords
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	RNA interference, targeting of mRNA for destruction Inferred from mutant phenotype. Source: FlyBase chromatin silencing Inferred from mutant phenotype. Source: FlyBase dorsal appendage formation Inferred from mutant phenotype. Source: FlyBase karyosome formation Traceable author statement. Source: FlyBase maintenance of pole plasm mRNA location Traceable author statement. Source: FlyBase negative regulation of transposition Inferred from mutant phenotype. Source: FlyBase oocyte maturation Inferred from mutant phenotype. Source: FlyBase pole cell formation Inferred from genetic interaction. Source: FlyBase pole plasm protein localization Inferred from mutant phenotype. Source: FlyBase positive regulation of oskar mRNA translation Non-traceable author statement. Source: FlyBase regulation of pole plasm oskar mRNA localization Inferred from mutant phenotype. Source: FlyBase
Cellular component	P granule Inferred from direct assay. Source: FlyBase
Molecular function	RNA binding Inferred from direct assay. Source: FlyBase
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	O76922-1 [UniParc]. Last modified November 1, 1998. Version 1. Checksum: 8F84CF1B0B89103B	FASTA	866	98,559
	10 20 30 40 50 60 MNLPPNPVIA RGRGRGRKPN NVEANRGFAP SLGQKSDPSH SEGNQASGGN GGGGDAQVGP 70 80 90 100 110 120 SIEKSSLSAV QMHKSEGDPR GSVRGRRLIT DLVYSRPPGM TSKKGVVGTH ITVQANYFKV 130 140 150 160 170 180 LKRPNWTIYQ YRVDFTPDVE ATRLRRSFLY EHKGILGGYI FDGTNMFCIN QFKAVQDSPY 190 200 210 220 230 240 VLELVTKSRA GENIEIKIKA VGSVQSTDAE QFQVLNLILR RAMEGLDLKL VSRYYYDPQA 250 260 270 280 290 300 KINLENFRMQ LWPGYQTSIR QHENDILLCS EICHKVMRTE TLYNILSDAI RDSDDYQSTF 310 320 330 340 350 360 KRAVMGMVIL TDYNNKTYRI DDVDFQSTPL CKFKTNDGEI SYVDYYKKRY NIIIRDLKQP 370 380 390 400 410 420 LVMSRPTDKN IRGGNDQAIM IIPELARATG MTDAMRADFR TLRAMSEHTR LNPDRRIERL 430 440 450 460 470 480 RMFNKRLKSC KQSVETLKSW NIELDSALVE IPARVLPPEK ILFGNQKIFV CDARADWTNE 490 500 510 520 530 540 FRTCSMFKNV HINRWYVITP SRNLRETQEF VQMCIRTASS MKMNICNPIY EEIPDDRNGT 550 560 570 580 590 600 YSQAIDNAAA NDPQIVMVVM RSPNEEKYSC IKKRTCVDRP VPSQVVTLKV IAPRQQKPTG 610 620 630 640 650 660 LMSIATKVVI QMNAKLMGAP WQVVIPLHGL MTVGFDVCHS PKNKNKSYGA FVATMDQKES 670 680 690 700 710 720 FRYFSTVNEH IKGQELSEQM SVNMACALRS YQEQHRSLPE RILFFRDGVG DGQLYQVVNS 730 740 750 760 770 780 EVNTLKDRLD EIYKSAGKQE GCRMTFIIVS KRINSRYFTG HRNPVPGTVV DDVITLPERY 790 800 810 820 830 840 DFFLVSQAVR IGTVSPTSYN VISDNMGLNA DKLQMLSYKM THMYYNYSGT IRVPAVCHYA 850 860 HKLAFLVAES INRAPSAGLQ NQLYFL

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review." Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E. Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed: 12537572] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
[2]	"The genome sequence of Drosophila melanogaster." Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C. Science 287:2185-2195(2000) [PubMed: 10731132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
[3]	"A newly identified Minute locus, M(2)32D, encodes the ribosomal protein L9 in Drosophila melanogaster." Schmidt A., Hollmann M., Schaefer U. Mol. Gen. Genet. 251:381-387(1996) [PubMed: 8676882] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: Canton S EMBL CAA64320.1.
[4]	"Genetic and molecular characterization of sting, a gene involved in crystal formation and meiotic drive in the male germ line of Drosophila melanogaster." Schmidt A., Palumbo G., Bozzetti M.P., Tritto P., Pimpinelli S., Schafer U. Genetics 151:749-760(1999) [PubMed: 9927466] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: Canton S EMBL CAA64320.1.
[5]	"Full Length Drosophila melanogaster cDNA sequence." Tsang G., Brokstein P., Frise E., Harvey D., Evans-Holm M., Lewis S.E., Suh C., Rubin G.M. Submitted (JUL-1999) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AF145680 mRNA. Translation: AAD38655.1. AE014134 Genomic DNA. Translation: AAF53046.1. X94613 Genomic DNA. Translation: CAA64320.1.
RefSeq	NP_476734.1.
UniGene	Dm.3112
3D structure databases
ModBase	Search...
Protein-protein interaction databases
IntAct	O76922. 2 interactions.
Proteomic databases
PRIDE	O76922.
Genome annotation databases
Ensembl	FBgn0000146. Drosophila melanogaster. [Contig view]
GeneID	34524.
NMPDR	fig|7227.3.peg.1944.
Organism-specific databases
FlyBase	FBgn0000146. aub.
Phylogenomic databases
HOGENOM	O76922.
OMA	O76922. ERYDFFL.
Gene expression databases
ArrayExpress	O76922.
Family and domain databases
InterPro	IPR003100. PAZ. IPR003165. Piwi. [Graphical view]
Pfam	PF02170. PAZ. 1 hit. PF02171. Piwi. 1 hit. [Graphical view]
PROSITE	PS50821. PAZ. 1 hit. PS50822. PIWI. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	788894.

Entry information

Entry name

O76922_DROME

Accession

Primary (citable) accession number: O76922

Entry history

Integrated into UniProtKB/TrEMBL:	November 1, 1998
Last sequence update:	November 1, 1998
Last modified:	June 16, 2009
This is version 58 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)