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Protein
Submitted name:

EG:80H7.4 protein

Gene

Rab27

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • exosomal secretion Source: FlyBase
  • melanosome transport Source: GO_Central
  • positive regulation of exocytosis Source: GO_Central
  • Rab protein signal transduction Source: FlyBase
  • sleep Source: FlyBase
  • vesicle-mediated transport Source: FlyBase

Enzyme and pathway databases

ReactomeiR-DME-114608. Platelet degranulation.
R-DME-6798695. Neutrophil degranulation.
R-DME-8876198. RAB GEFs exchange GTP for GDP on RABs.

Names & Taxonomyi

Protein namesi
Submitted name:
EG:80H7.4 proteinImported
Submitted name:
LP12150pImported
Submitted name:
Rab27, isoform BImported
Gene namesi
Name:Rab27Imported
Synonyms:18543235Imported, AAF45634Imported, AAF45635Imported, dm-Rab27Imported, Dmel\CG14791Imported, DmRab27Imported, EG:80H7.4Imported, O76901Imported, rab27Imported, Rab27-RBImported
ORF Names:CG14791Imported, Dmel_CG14791Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome X

Organism-specific databases

FlyBaseiFBgn0025382. Rab27.

Subcellular locationi

Expressioni

Gene expression databases

BgeeiFBgn0025382.

Interactioni

Protein-protein interaction databases

DIPiDIP-21950N.
IntActiO76901. 2 interactors.
MINTiMINT-822877.
STRINGi7227.FBpp0070280.

Family & Domainsi

Phylogenomic databases

eggNOGiKOG0081. Eukaryota.
ENOG410XQ3T. LUCA.
GeneTreeiENSGT00890000139417.
OMAiLVMQRIQ.
OrthoDBiEOG091G0I51.

Family and domain databases

InterProiView protein in InterPro
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR001806. Small_GTPase.
PfamiView protein in Pfam
PF00071. Ras. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00231. small_GTP. 1 hit.

Sequencei

Sequence statusi: Complete.

O76901-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRAAPPEPEP LQLAGSGEQF LVLGDSGVGK TCLLYQYTDG RFHTQFISTV
60 70 80 90 100
GIDFREKRLL YNSRGRRHRI HLQIWDTAGQ ERFRSLTTAF YRDAMGFLLI
110 120 130 140 150
FDLTSEKSFL ETANWLSQLR THAYSEDPDV VLCGNKCDLL QLRVVSRDQV
160 170 180 190 200
AALCRRYRLP YIETSACTGA NVKEAVELLV GRVMERIENA ACNREFSLLL
210 220 230
TQSRCLPNIA YGQPEDLVRL HDRREEPCSR RNCRNC
Length:236
Mass (Da):27,081
Last modified:November 1, 1999 - v2
Checksum:i6F482F0F7C9C050C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014298 Genomic DNA. Translation: AAF45635.1.
BT125812 mRNA. Translation: ADR71721.1.
AL031027 Genomic DNA. Translation: CAA19844.2.
PIRiT13599.
RefSeqiNP_726743.1. NM_166888.3.
UniGeneiDm.14.

Genome annotation databases

EnsemblMetazoaiFBtr0070293; FBpp0070280; FBgn0025382.
GeneIDi31103.
UCSCiCG14791-RB. d. melanogaster.

Similar proteinsi

Entry informationi

Entry nameiO76901_DROME
AccessioniPrimary (citable) accession number: O76901
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1998
Last sequence update: November 1, 1999
Last modified: September 27, 2017
This is version 159 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported