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Protein
Submitted name:

Extended SYnapTotagmin homolog

Gene

esyt-2

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Extended SYnapTotagmin homologImported
Gene namesi
Name:esyt-2Imported
ORF Names:CELE_T12A2.15Imported, T12A2.15Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome III

Organism-specific databases

WormBaseiT12A2.15a; CE30392; WBGene00020443; esyt-2.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei7 – 24HelicalSequence analysisAdd BLAST18
Transmembranei30 – 47HelicalSequence analysisAdd BLAST18

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

EPDiO76835.
PaxDbiO76835.
PeptideAtlasiO76835.

Expressioni

Gene expression databases

BgeeiWBGene00020443.
ExpressionAtlasiO76835. differential.

Interactioni

Protein-protein interaction databases

STRINGi6239.T12A2.15a.

Structurei

3D structure databases

ProteinModelPortaliO76835.
SMRiO76835.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini278 – 362C2InterPro annotationAdd BLAST85
Domaini425 – 503C2InterPro annotationAdd BLAST79
Domaini593 – 690C2InterPro annotationAdd BLAST98

Sequence similaritiesi

Contains 3 C2 domains.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG1012. Eukaryota.
KOG1013. Eukaryota.
ENOG410XPR4. LUCA.
GeneTreeiENSGT00550000074417.
HOGENOMiHOG000021105.
InParanoidiO76835.
OMAiFKEDDME.
OrthoDBiEOG091G02X7.
PhylomeDBiO76835.

Family and domain databases

Gene3Di2.60.40.150. 3 hits.
InterProiIPR000008. C2_dom.
IPR031468. SMP_LBD.
[Graphical view]
PfamiPF00168. C2. 3 hits.
PF17047. SMP_LBD. 1 hit.
[Graphical view]
SMARTiSM00239. C2. 3 hits.
[Graphical view]
SUPFAMiSSF49562. SSF49562. 3 hits.
PROSITEiPS50004. C2. 3 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O76835-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSWQSYLVPL VGSAILSTFT FFLGKWDYSF VWVLIIIIAS VTKSYLWRKR
60 70 80 90 100
ERRLIALRAT ALREREVIMA QLQDLPAWVQ FPDTERVEWL NKVIHQLWPY
110 120 130 140 150
VGEYTKTFMN DFIIPQVKAQ MPGMFKNFKF TKMDMGDIPC RVGGIKVYTT
160 170 180 190 200
NVGRDRIIVD MDVAYAGDAD FTVSCCGFTG GMNNIQFSGK LRAILKPLLP
210 220 230 240 250
YPPMVGGVSG TFLEMPKMDF NLTGMGEMVE LPGLIDAIRS VINSQIAALC
260 270 280 290 300
VLPNEIVVPL APDVDVTQLY FPEPDGVVRL KIIEAKNLEN RDISFIKKGK
310 320 330 340 350
SDPYAEIQVG SQFFKTRTID DDLNPIWNEY FEAVVDQADG QKLRIELFDE
360 370 380 390 400
DQGKDEELGR LSVDLKLVQA KGTIDKWYPL EGCKHGDLHI KATWMNLSTE
410 420 430 440 450
LRHLEKQEWE AEWGQADKPI HSALLMVYID SVADLPYPKS KLEPSPFVEV
460 470 480 490 500
SLGKETQRTP VKVKTVNPLF QSKFLFFVRH LEGQELKFEA VDDGTRRSLG
510 520 530 540 550
SLNIPLTTLL KEPNLEQNQQ MHMLTLGVHQ SPIVITTRIR MLRSDSQGSL
560 570 580 590 600
NSHGRSNSRL GRLFRSKHEM KKRETRADEN RGEIEIQIDF DDLVNQLKIA
610 620 630 640 650
LIRCRDLMTF DKKDQCNPYV SVKLVALDGN KEVFKKKTPT AKNTRHPHFD
660 670 680 690 700
NHVEIDINPS DLLNHKVVIN VKDDTNYGTF VAKPVLGCLE IRLDSLMNRQ
710
LSQRWIPLSV ERK
Length:713
Mass (Da):81,550
Last modified:June 1, 2002 - v2
Checksum:i32E3EDCDCE49CE42
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284603 Genomic DNA. Translation: CCD65219.1.
PIRiT34345.
RefSeqiNP_741181.1. NM_171156.3.
UniGeneiCel.7773.

Genome annotation databases

EnsemblMetazoaiT12A2.15a; T12A2.15a; WBGene00020443.
GeneIDi175882.
KEGGicel:CELE_T12A2.15.
UCSCiT12A2.15b. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284603 Genomic DNA. Translation: CCD65219.1.
PIRiT34345.
RefSeqiNP_741181.1. NM_171156.3.
UniGeneiCel.7773.

3D structure databases

ProteinModelPortaliO76835.
SMRiO76835.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi6239.T12A2.15a.

Proteomic databases

EPDiO76835.
PaxDbiO76835.
PeptideAtlasiO76835.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiT12A2.15a; T12A2.15a; WBGene00020443.
GeneIDi175882.
KEGGicel:CELE_T12A2.15.
UCSCiT12A2.15b. c. elegans.

Organism-specific databases

CTDi175882.
WormBaseiT12A2.15a; CE30392; WBGene00020443; esyt-2.

Phylogenomic databases

eggNOGiKOG1012. Eukaryota.
KOG1013. Eukaryota.
ENOG410XPR4. LUCA.
GeneTreeiENSGT00550000074417.
HOGENOMiHOG000021105.
InParanoidiO76835.
OMAiFKEDDME.
OrthoDBiEOG091G02X7.
PhylomeDBiO76835.

Gene expression databases

BgeeiWBGene00020443.
ExpressionAtlasiO76835. differential.

Family and domain databases

Gene3Di2.60.40.150. 3 hits.
InterProiIPR000008. C2_dom.
IPR031468. SMP_LBD.
[Graphical view]
PfamiPF00168. C2. 3 hits.
PF17047. SMP_LBD. 1 hit.
[Graphical view]
SMARTiSM00239. C2. 3 hits.
[Graphical view]
SUPFAMiSSF49562. SSF49562. 3 hits.
PROSITEiPS50004. C2. 3 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiO76835_CAEEL
AccessioniPrimary (citable) accession number: O76835
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1998
Last sequence update: June 1, 2002
Last modified: November 30, 2016
This is version 114 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.