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Protein

PBAN-type neuropeptides

Gene
N/A
Organism
Agrotis ipsilon (Black cutworm moth)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

PBAN is a hormone that controls sex pheromone production in female moths and pheromone responsiveness in male. PBAN also mediates visceral muscle contractile activity (myotropic activity).1 Publication

Miscellaneous

Juvenile hormone seems to allow PBAN release, which then induces pheromone biosynthesis.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHormone, Neuropeptide
Biological processPheromone response

Names & Taxonomyi

Protein namesi
Recommended name:
PBAN-type neuropeptides
Alternative name(s):
Pheromone/pyrokinin biosynthesis-activating neuropeptide
Cleaved into the following 5 chains:
Alternative name(s):
Pyrokinin-1
Alternative name(s):
Pyrokinin-2
Alternative name(s):
Pyrokinin-3
OrganismiAgrotis ipsilon (Black cutworm moth)
Taxonomic identifieri56364 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaLepidopteraGlossataDitrysiaNoctuoideaNoctuidaeNoctuinaeAgrotis

Subcellular locationi

  • Secreted 1 Publication

GO - Cellular componenti

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 22Sequence analysisAdd BLAST22
PeptideiPRO_000002991423 – 46Diapause hormone homologSequence analysisAdd BLAST24
PropeptideiPRO_000002991550 – 93Add BLAST44
PeptideiPRO_000002991696 – 102Alpha-SG neuropeptideSequence analysis7
PeptideiPRO_0000029917105 – 122Beta-SG neuropeptideSequence analysisAdd BLAST18
PeptideiPRO_0000029918126 – 158Pheromone biosynthesis-activating neuropeptideAdd BLAST33
PeptideiPRO_0000029919161 – 168Gamma-SG neuropeptideSequence analysis8
PropeptideiPRO_0000029920171 – 193Add BLAST23

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei46Isoleucine amideBy similarity1
Modified residuei102Leucine amideBy similarity1
Modified residuei122Leucine amideBy similarity1
Modified residuei158Leucine amideBy similarity1
Modified residuei168Leucine amideBy similarity1

Keywords - PTMi

Amidation, Cleavage on pair of basic residues

Expressioni

Tissue specificityi

Expressed in the mandibular, maxillary and labial neuromeres of the male and female brain-subesophageal ganglions, in the corpora cardiaca and all around the corpora allata, and at a lower level in the brain near the calyx and pedunculus of the mushroom body. Expressed in larvae and adult of both sexes.1 Publication

Interactioni

GO - Molecular functioni

Family & Domainsi

Sequence similaritiesi

Belongs to the pyrokinin family.Curated

Keywords - Domaini

Signal

Family and domain databases

InterProiView protein in InterPro
IPR008730. PBAN.
IPR001484. Pyrokinin_CS.
PfamiView protein in Pfam
PF05874. PBAN. 1 hit.
PROSITEiView protein in PROSITE
PS00539. PYROKININ. 3 hits.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

O76818-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYGAVLPGLF FIFISCVVAS SNDVKDGGAD RGAHSDRGGM WFGPRIGKRS
60 70 80 90 100
LRMATEDNRQ AFFKLLEAAD ALKYYYDQLP YEMQADEPEA RVTKKVIFTP
110 120 130 140 150
KLGRSLSYED KMFDNVEFTP RLGRRLADDT PATPADQEMY RPDPEQIDSR
160 170 180 190
TKYFSPRLGR TMNFSPRLGR ELAYEMLPSK VRVVRSTNKT QST
Length:193
Mass (Da):22,014
Last modified:November 1, 1998 - v1
Checksum:i7F66D4080430DE18
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ009674 mRNA. Translation: CAA08774.1.

Similar proteinsi

Entry informationi

Entry nameiPBAN_AGRIP
AccessioniPrimary (citable) accession number: O76818
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 15, 1999
Last sequence update: November 1, 1998
Last modified: May 10, 2017
This is version 55 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families