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Protein
Submitted name:

Aminopeptidase N

Gene

APN

Organism
Bombyx mori (Silk moth)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

AminopeptidaseImported, Hydrolase, Protease

Protein family/group databases

MEROPSiM01.013.

Names & Taxonomyi

Protein namesi
Submitted name:
Aminopeptidase NImported
Submitted name:
Aminopeptidase N-4Imported
Gene namesi
Name:APNImported
OrganismiBombyx mori (Silk moth)Imported
Taxonomic identifieri7091 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaLepidopteraGlossataDitrysiaBombycoideaBombycidaeBombycinaeBombyx

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2020Sequence analysisAdd
BLAST
Chaini21 – 986966Sequence analysisPRO_5007697104Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi7091.BGIBMGA008059-TA.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini44 – 449406Peptidase_M1InterPro annotationAdd
BLAST
Domaini594 – 910317ERAP1_CInterPro annotationAdd
BLAST

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG1046. Eukaryota.
COG0308. LUCA.
KOiK11140.

Family and domain databases

InterProiIPR024571. ERAP1-like_C_dom.
IPR001930. Peptidase_M1.
IPR014782. Peptidase_M1_N.
[Graphical view]
PANTHERiPTHR11533. PTHR11533. 1 hit.
PfamiPF11838. ERAP1_C. 1 hit.
PF01433. Peptidase_M1. 1 hit.
[Graphical view]
PRINTSiPR00756. ALADIPTASE.

Sequencei

Sequence statusi: Complete.

O76803-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASRWFYFLV GVAFLQTSLT LSPIPVPEDE WVEFARMLRD PAFRLPTTTR
60 70 80 90 100
PRHYQVTLTP YFDVVPANVN PFTFDGEVTI YTSPTVANVN EVVIHCNDLT
110 120 130 140 150
IQSLSIGYQS GTNVVDITAT GQTFACEMPF SFLRIRTTEA LVLNREYIIK
160 170 180 190 200
STFRGNLQTN MRGFYRSWYV DSTGRRWMGT TQFQPGHARQ AFPCYDEPGF
210 220 230 240 250
KATFDITMNR EESFSPTISN MPIRTTNTLA NGRVSETFWT TPVTSTYLLA
260 270 280 290 300
FIVSHYTVVS TNNNALRPFD IYARNNVGRT GDWSLEIGEK LLEAMEAYTQ
310 320 330 340 350
IPYYTMAENI NMKQAAIPDF SAGAMENWGL LTYREALILY DPLNSNHFYK
360 370 380 390 400
QRVANIVAHE IAHMWFGNLV TCAWWDNLWL NEGFARFYQY YLTASVAPEL
410 420 430 440 450
GYETRFIVEQ VQMAMFSDSV DTAHALTDLN VNDPTTVSAH FSTITYARGA
460 470 480 490 500
AILRMTQHLL GVETFVKGLR NYLRERQFNV AEPHHLFTAL DAAAVEDGAL
510 520 530 540 550
NGYGGITIDT YFRTWSEKAG HPLLTVTINQ RTGEMIVTQE RWERNTGVSQ
560 570 580 590 600
FPSLWHIPIT WTRAGAPEFE DLKPSQFISQ QVTSINRGTT GLEWVIFNKQ
610 620 630 640 650
EAGFYRVNYD DTNWALLTRA LRSSSRTAIH QLNRAQIVDD IFQLARANVM
660 670 680 690 700
KYNRAFNILS FLQFEDEYAP WLAAISGFNF LIRRLAHDST NAALLQKLIL
710 720 730 740 750
ELSPAVVAKL GYLEPENGSY MTDLQRMYVM EFLCNVGHEE CNNFGTQAFR
760 770 780 790 800
RWSTGTFIPA NMRPWVYCAG LRHGTAEDFN FFWNRYLQED LSSEKVVMLN
810 820 830 840 850
VAGCTTDQAS LNRFLDAIVS GNDDIRPQDY NAALTSAITS NEINTLRAFQ
860 870 880 890 900
WLRNNVDQAT RTLGSVSTIL NTIIGRLLNE EQINEVSNWL TANQNTLGAT
910 920 930 940 950
YSTALRAIET TRSNLVWSQQ RISEFTNYFE SGYVEDVIEE ITEAPPTAPP
960 970 980
TAPPTEAPAV TPAPDSANVA ALSFITLIIT LAVNLA
Length:986
Mass (Da):111,696
Last modified:November 1, 1998 - v1
Checksum:iDEB5A55F904BD5F1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF084257 mRNA. Translation: AAC33301.1.
JQ061146 mRNA. Translation: AFK85020.1.
RefSeqiNP_001037013.1. NM_001043548.1.
UniGeneiBmo.769.

Genome annotation databases

GeneIDi692563.
KEGGibmor:692563.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF084257 mRNA. Translation: AAC33301.1.
JQ061146 mRNA. Translation: AFK85020.1.
RefSeqiNP_001037013.1. NM_001043548.1.
UniGeneiBmo.769.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7091.BGIBMGA008059-TA.

Protein family/group databases

MEROPSiM01.013.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi692563.
KEGGibmor:692563.

Organism-specific databases

CTDi692563.

Phylogenomic databases

eggNOGiKOG1046. Eukaryota.
COG0308. LUCA.
KOiK11140.

Family and domain databases

InterProiIPR024571. ERAP1-like_C_dom.
IPR001930. Peptidase_M1.
IPR014782. Peptidase_M1_N.
[Graphical view]
PANTHERiPTHR11533. PTHR11533. 1 hit.
PfamiPF11838. ERAP1_C. 1 hit.
PF01433. Peptidase_M1. 1 hit.
[Graphical view]
PRINTSiPR00756. ALADIPTASE.
ProtoNetiSearch...

Publicationsi

  1. "cDNA cloning and expression of Bacillus thuringiensis Cry1Aa toxin binding 120 kDa aminopeptidase N from Bombyx mori."
    Yaoi K., Nakanishi K., Kadotani T., Imamura M., Koizumi N., Iwahana H., Sato R.
    Biochim. Biophys. Acta 1444:131-137(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: MidgutImported.
  2. "Identification and analysis of aminopeptidase N family genes in the silkworm, Bombyx mori."
    Wang J.H., Shi X.S., Liu X.J., Jiang F., Wang G.Z., Li Y.N., Zhang Z.F.
    Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiO76803_BOMMO
AccessioniPrimary (citable) accession number: O76803
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1998
Last sequence update: November 1, 1998
Last modified: July 6, 2016
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.