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Protein
Submitted name:

CG12117-PA

Gene

Sptr

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • sepiapterin reductase activity Source: FlyBase

GO - Biological processi

Keywordsi

Molecular functionOxidoreductaseImported

Enzyme and pathway databases

ReactomeiR-DME-1474151 Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
R-DME-203615 eNOS activation

Names & Taxonomyi

Protein namesi
Submitted name:
CG12117-PAImported
Submitted name:
GH04031pImported
Submitted name:
Sepiapterin reductaseImported (EC:1.1.1.153Imported)
Gene namesi
Name:SptrImported
Synonyms:Dmel\CG12117Imported, sptrImported, SRImported
ORF Names:CG12117Imported, Dmel_CG12117Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome X

Organism-specific databases

FlyBaseiFBgn0014032 Sptr

Expressioni

Gene expression databases

BgeeiFBgn0014032

Interactioni

Protein-protein interaction databases

IntActiO76752, 1 interactor
STRINGi7227.FBpp0071184

Structurei

3D structure databases

SMRiO76752
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiKOG1204 Eukaryota
ENOG4111PZG LUCA
GeneTreeiENSGT00440000033609
KOiK00072
OMAiAFKFKSG
OrthoDBiEOG091G0N30

Family and domain databases

InterProiView protein in InterPro
IPR036291 NAD(P)-bd_dom_sf
IPR002347 SDR_fam
IPR006393 Sepiapterin_red
PfamiView protein in Pfam
PF00106 adh_short, 1 hit
PRINTSiPR00081 GDHRDH
SUPFAMiSSF51735 SSF51735, 1 hit
TIGRFAMsiTIGR01500 sepiapter_red, 1 hit

Sequencei

Sequence statusi: Complete.

O76752-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDLKQRTYLL VTGASRGIGR EFAQQLAKRI KAEGSMVTLL GRNQTLLQES
60 70 80 90 100
KAEIVATVPD LSVQTYSLEL ETAKTEDFTK ILEASGGKNN FERAIVIHNA
110 120 130 140 150
GTVGDTSKRA KEIGDTDFLQ RYYHSNVFSA ISLNCEFMRV FKGIPKLVVN
160 170 180 190 200
LSTLAAIAPI SSMAHYCTVK AAREMYFRVL ATEESAEDTL VLNYAPGVID
210 220 230 240 250
TQMTVQVQRE AHDPAVVAMF REQRESKTML TPAQTTERFI KVLEAFKFKS
260
GDHVDYRDEQ F
Length:261
Mass (Da):29,231
Last modified:November 1, 1998 - v1
Checksum:i48DB42F94DFDBBA1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF080266 mRNA Translation: AAD12760.1
AF167284 Genomic DNA Translation: AAF00619.1
AE014298 Genomic DNA Translation: AAF46376.1
AY118731 mRNA Translation: AAM50591.1
AM999091 Genomic DNA Translation: CAQ53453.1
AM999093 Genomic DNA Translation: CAQ53455.1
AM999095 Genomic DNA Translation: CAQ53457.1
AM999096 Genomic DNA Translation: CAQ53458.1
AM999101 Genomic DNA Translation: CAQ53463.1
FM246209 Genomic DNA Translation: CAR94135.1
FM246210 Genomic DNA Translation: CAR94136.1
FM246212 Genomic DNA Translation: CAR94138.1
FM246214 Genomic DNA Translation: CAR94140.1
FM246218 Genomic DNA Translation: CAR94144.1
RefSeqiNP_727265.1, NM_167157.2
UniGeneiDm.1950

Genome annotation databases

EnsemblMetazoaiFBtr0071241; FBpp0071184; FBgn0014032
GeneIDi31781
KEGGidme:Dmel_CG12117
UCSCiCG12117-RA d. melanogaster

Similar proteinsi

Entry informationi

Entry nameiO76752_DROME
AccessioniPrimary (citable) accession number: O76752
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1998
Last sequence update: November 1, 1998
Last modified: March 28, 2018
This is version 148 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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Main funding by: National Institutes of Health