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Protein
Submitted name:

CG12117-PA

Gene

Sptr

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • sepiapterin reductase activity Source: FlyBase

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseImported

Enzyme and pathway databases

ReactomeiR-DME-1474151. Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation.

Names & Taxonomyi

Protein namesi
Submitted name:
CG12117-PAImported
Submitted name:
GH04031pImported
Submitted name:
Sepiapterin reductaseImported (EC:1.1.1.153Imported)
Gene namesi
Name:SptrImported
ORF Names:CG12117Imported, Dmel_CG12117Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome X

Organism-specific databases

FlyBaseiFBgn0014032. Sptr.

Expressioni

Gene expression databases

BgeeiFBgn0014032.

Interactioni

Protein-protein interaction databases

STRINGi7227.FBpp0071184.

Family & Domainsi

Phylogenomic databases

eggNOGiKOG1204. Eukaryota.
ENOG4111PZG. LUCA.
GeneTreeiENSGT00440000033609.
KOiK00072.
OMAiSGDHIDY.
OrthoDBiEOG091G0N30.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
InterProiIPR016040. NAD(P)-bd_dom.
IPR002347. SDR_fam.
IPR006393. Sepiapterin_red.
[Graphical view]
PANTHERiPTHR24322. PTHR24322. 2 hits.
PfamiPF00106. adh_short. 1 hit.
[Graphical view]
PRINTSiPR00081. GDHRDH.
SUPFAMiSSF51735. SSF51735. 1 hit.
TIGRFAMsiTIGR01500. sepiapter_red. 1 hit.

Sequencei

Sequence statusi: Complete.

O76752-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDLKQRTYLL VTGASRGIGR EFAQQLAKRI KAEGSMVTLL GRNQTLLQES
60 70 80 90 100
KAEIVATVPD LSVQTYSLEL ETAKTEDFTK ILEASGGKNN FERAIVIHNA
110 120 130 140 150
GTVGDTSKRA KEIGDTDFLQ RYYHSNVFSA ISLNCEFMRV FKGIPKLVVN
160 170 180 190 200
LSTLAAIAPI SSMAHYCTVK AAREMYFRVL ATEESAEDTL VLNYAPGVID
210 220 230 240 250
TQMTVQVQRE AHDPAVVAMF REQRESKTML TPAQTTERFI KVLEAFKFKS
260
GDHVDYRDEQ F
Length:261
Mass (Da):29,231
Last modified:November 1, 1998 - v1
Checksum:i48DB42F94DFDBBA1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF080266 mRNA. Translation: AAD12760.1.
AF167284 Genomic DNA. Translation: AAF00619.1.
AE014298 Genomic DNA. Translation: AAF46376.1.
AY118731 mRNA. Translation: AAM50591.1.
AM999091 Genomic DNA. Translation: CAQ53453.1.
AM999093 Genomic DNA. Translation: CAQ53455.1.
AM999095 Genomic DNA. Translation: CAQ53457.1.
AM999096 Genomic DNA. Translation: CAQ53458.1.
AM999101 Genomic DNA. Translation: CAQ53463.1.
FM246209 Genomic DNA. Translation: CAR94135.1.
FM246210 Genomic DNA. Translation: CAR94136.1.
FM246212 Genomic DNA. Translation: CAR94138.1.
FM246214 Genomic DNA. Translation: CAR94140.1.
FM246218 Genomic DNA. Translation: CAR94144.1.
RefSeqiNP_727265.1. NM_167157.2.
UniGeneiDm.1950.

Genome annotation databases

EnsemblMetazoaiFBtr0071241; FBpp0071184; FBgn0014032.
GeneIDi31781.
KEGGidme:Dmel_CG12117.
UCSCiCG12117-RA. d. melanogaster.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF080266 mRNA. Translation: AAD12760.1.
AF167284 Genomic DNA. Translation: AAF00619.1.
AE014298 Genomic DNA. Translation: AAF46376.1.
AY118731 mRNA. Translation: AAM50591.1.
AM999091 Genomic DNA. Translation: CAQ53453.1.
AM999093 Genomic DNA. Translation: CAQ53455.1.
AM999095 Genomic DNA. Translation: CAQ53457.1.
AM999096 Genomic DNA. Translation: CAQ53458.1.
AM999101 Genomic DNA. Translation: CAQ53463.1.
FM246209 Genomic DNA. Translation: CAR94135.1.
FM246210 Genomic DNA. Translation: CAR94136.1.
FM246212 Genomic DNA. Translation: CAR94138.1.
FM246214 Genomic DNA. Translation: CAR94140.1.
FM246218 Genomic DNA. Translation: CAR94144.1.
RefSeqiNP_727265.1. NM_167157.2.
UniGeneiDm.1950.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7227.FBpp0071184.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0071241; FBpp0071184; FBgn0014032.
GeneIDi31781.
KEGGidme:Dmel_CG12117.
UCSCiCG12117-RA. d. melanogaster.

Organism-specific databases

CTDi31781.
FlyBaseiFBgn0014032. Sptr.

Phylogenomic databases

eggNOGiKOG1204. Eukaryota.
ENOG4111PZG. LUCA.
GeneTreeiENSGT00440000033609.
KOiK00072.
OMAiSGDHIDY.
OrthoDBiEOG091G0N30.

Enzyme and pathway databases

ReactomeiR-DME-1474151. Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation.

Miscellaneous databases

GenomeRNAii31781.

Gene expression databases

BgeeiFBgn0014032.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
InterProiIPR016040. NAD(P)-bd_dom.
IPR002347. SDR_fam.
IPR006393. Sepiapterin_red.
[Graphical view]
PANTHERiPTHR24322. PTHR24322. 2 hits.
PfamiPF00106. adh_short. 1 hit.
[Graphical view]
PRINTSiPR00081. GDHRDH.
SUPFAMiSSF51735. SSF51735. 1 hit.
TIGRFAMsiTIGR01500. sepiapter_red. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiO76752_DROME
AccessioniPrimary (citable) accession number: O76752
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1998
Last sequence update: November 1, 1998
Last modified: September 7, 2016
This is version 133 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.