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Protein
Submitted name:

CG5915 protein

Gene

Rab7

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • GTPase activity Source: FlyBase
  • GTP binding Source: InterPro
  • protein complex binding Source: FlyBase

GO - Biological processi

  • autophagic cell death Source: FlyBase
  • border follicle cell migration Source: FlyBase
  • clathrin-dependent endocytosis involved in vitellogenesis Source: FlyBase
  • dsRNA transport Source: FlyBase
  • endocytosis Source: FlyBase
  • endosomal transport Source: FlyBase
  • endosome to lysosome transport Source: FlyBase
  • endosome to lysosome transport via multivesicular body sorting pathway Source: FlyBase
  • exosomal secretion Source: FlyBase
  • negative regulation of growth of symbiont in host Source: FlyBase
  • Rab protein signal transduction Source: FlyBase
  • regulation of Notch signaling pathway Source: FlyBase
  • salivary gland cell autophagic cell death Source: FlyBase
  • vesicle-mediated transport Source: FlyBase
  • wing disc dorsal/ventral pattern formation Source: FlyBase

Names & Taxonomyi

Protein namesi
Submitted name:
CG5915 proteinImported
Submitted name:
CG5915-PAImported
Submitted name:
GH03685pImported
Submitted name:
MIP21169pImported
Submitted name:
Rab7 proteinImported
Submitted name:
Rab7, isoform AImported
Submitted name:
Rab7, isoform BImported
Submitted name:
Rab7, isoform CImported
Submitted name:
Small ras-like GTPaseImported
Submitted name:
Small ras-like GTPase RAB7Imported
Gene namesi
Name:Rab7Imported
Synonyms:AAF56218Imported, Dm Rab7Imported, Dmel\CG5915Imported, DmRab7Imported, DRAB7Imported, DRab7Imported, Drab7Imported, dRab7Imported, drab7Imported, O76742Imported, Rab-7Imported, Rab-r7Imported, RAB7Imported, rab7Imported, Rab7AImported
ORF Names:CG5915Imported, Dmel_CG5915Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 3R

Organism-specific databases

FlyBaseiFBgn0015795. Rab7.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiFBgn0015795.

Interactioni

GO - Molecular functioni

  • protein complex binding Source: FlyBase

Protein-protein interaction databases

IntActiO76742. 4 interactors.
MINTiMINT-1017301.
STRINGi7227.FBpp0083891.

Family & Domainsi

Phylogenomic databases

eggNOGiKOG0394. Eukaryota.
ENOG410XNZV. LUCA.
GeneTreeiENSGT00760000119125.
KOiK07897.
OMAiLMQQFVN.
OrthoDBiEOG091G0JIV.

Family and domain databases

InterProiView protein in InterPro
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR001806. Small_GTPase.
PfamiView protein in Pfam
PF00071. Ras. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00231. small_GTP. 1 hit.

Sequencei

Sequence statusi: Complete.

O76742-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSGRKKSLLK VIILGDSSVG KTSLMNQYVN KRFSNQYKAT IGADFCTKEV
60 70 80 90 100
VVNDRVVTMQ IWDTAGQERF QSLGVAFYRG ADCCVLVYDV TAPNSFKNLD
110 120 130 140 150
SWRDEFLIQA SPRDPDHFPF VVLGNKVDLD NRQVSTRRAQ QWCQSKNDIP
160 170 180 190 200
YYETSAKEGI NVEMAFQVIA KNALELEAEA EVINDFPDQI TLGSQNNRPG

NPDNCQC
Length:207
Mass (Da):23,331
Last modified:November 1, 1998 - v1
Checksum:iFFC76D3630287AEB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF079459 Genomic DNA. Translation: AAC32270.1.
AE014297 Genomic DNA. Translation: AAF56218.1.
AF263363 mRNA. Translation: AAF73041.1.
AY060236 mRNA. Translation: AAL25275.1.
BT124755 mRNA. Translation: ADF28796.1.
AE014297 Genomic DNA. Translation: AFH06594.1.
AE014297 Genomic DNA. Translation: AFH06595.1.
AB035672 mRNA. Translation: BAA88245.1.
AM294823 Genomic DNA. Translation: CAL26809.1.
AM294824 Genomic DNA. Translation: CAL26810.1.
AM294825 Genomic DNA. Translation: CAL26811.1.
AM294826 Genomic DNA. Translation: CAL26812.1.
AM294827 Genomic DNA. Translation: CAL26813.1.
AM294828 Genomic DNA. Translation: CAL26814.1.
AM294829 Genomic DNA. Translation: CAL26815.1.
AM294830 Genomic DNA. Translation: CAL26816.1.
AM294831 Genomic DNA. Translation: CAL26817.1.
AM294832 Genomic DNA. Translation: CAL26818.1.
AM294833 Genomic DNA. Translation: CAL26819.1.
FM245635 Genomic DNA. Translation: CAR93561.1.
FM245636 Genomic DNA. Translation: CAR93562.1.
FM245637 Genomic DNA. Translation: CAR93563.1.
FM245638 Genomic DNA. Translation: CAR93564.1.
FM245639 Genomic DNA. Translation: CAR93565.1.
FM245640 Genomic DNA. Translation: CAR93566.1.
FM245641 Genomic DNA. Translation: CAR93567.1.
FM245642 Genomic DNA. Translation: CAR93568.1.
FM245643 Genomic DNA. Translation: CAR93569.1.
FM245644 Genomic DNA. Translation: CAR93570.1.
FM245645 Genomic DNA. Translation: CAR93571.1.
RefSeqiNP_001247276.1. NM_001260347.1.
NP_001247277.1. NM_001260348.2.
NP_524472.1. NM_079748.4.
UniGeneiDm.1701.

Genome annotation databases

EnsemblMetazoaiFBtr0084503; FBpp0083891; FBgn0015795.
FBtr0308611; FBpp0300835; FBgn0015795.
FBtr0308612; FBpp0300836; FBgn0015795.
GeneIDi42841.
KEGGidme:Dmel_CG5915.
UCSCiCG5915-RA. d. melanogaster.

Similar proteinsi

Entry informationi

Entry nameiO76742_DROME
AccessioniPrimary (citable) accession number: O76742
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1998
Last sequence update: November 1, 1998
Last modified: September 27, 2017
This is version 152 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported