Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

CG5915 protein

Gene

Rab7

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • GTPase activity Source: FlyBase
  • GTP binding Source: InterPro
  • protein-containing complex binding Source: FlyBase

GO - Biological processi

  • border follicle cell migration Source: FlyBase
  • clathrin-dependent endocytosis involved in vitellogenesis Source: FlyBase
  • dsRNA transport Source: FlyBase
  • endocytosis Source: FlyBase
  • endosomal transport Source: FlyBase
  • endosome to lysosome transport Source: FlyBase
  • endosome to lysosome transport via multivesicular body sorting pathway Source: FlyBase
  • exosomal secretion Source: FlyBase
  • negative regulation of growth of symbiont in host Source: FlyBase
  • Rab protein signal transduction Source: FlyBase
  • regulation of Notch signaling pathway Source: FlyBase
  • vesicle-mediated transport Source: FlyBase
  • wing disc dorsal/ventral pattern formation Source: FlyBase

Enzyme and pathway databases

ReactomeiR-DME-6798695 Neutrophil degranulation
R-DME-8854214 TBC/RABGAPs
R-DME-8873719 RAB geranylgeranylation
R-DME-8876198 RAB GEFs exchange GTP for GDP on RABs

Names & Taxonomyi

Protein namesi
Submitted name:
CG5915 proteinImported
Submitted name:
CG5915-PAImported
Submitted name:
GH03685pImported
Submitted name:
MIP21169pImported
Submitted name:
Rab7 proteinImported
Submitted name:
Rab7, isoform AImported
Submitted name:
Rab7, isoform BImported
Submitted name:
Rab7, isoform CImported
Submitted name:
Small ras-like GTPaseImported
Submitted name:
Small ras-like GTPase RAB7Imported
Gene namesi
Name:Rab7Imported
Synonyms:AAF56218Imported, Dm Rab7Imported, Dmel\CG5915Imported, DmRab7Imported, DRAB7Imported, DRab7Imported, Drab7Imported, dRab7Imported, drab7Imported, O76742Imported, Rab-7Imported, Rab-r7Imported, RAB7Imported, rab7Imported, Rab7AImported
ORF Names:CG5915Imported, Dmel_CG5915Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 3R

Organism-specific databases

FlyBaseiFBgn0015795 Rab7

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiFBgn0015795

Interactioni

Protein-protein interaction databases

IntActiO76742 4 interactors.
STRINGi7227.FBpp0083891

Structurei

3D structure databases

SMRiO76742
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiKOG0394 Eukaryota
ENOG410XNZV LUCA
GeneTreeiENSGT00760000119125
KOiK07897
OMAiLMQQFVN
OrthoDBiEOG091G0JIV

Family and domain databases

InterProiView protein in InterPro
IPR027417 P-loop_NTPase
IPR005225 Small_GTP-bd_dom
IPR001806 Small_GTPase
PfamiView protein in Pfam
PF00071 Ras, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR00231 small_GTP, 1 hit

Sequencei

Sequence statusi: Complete.

O76742-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSGRKKSLLK VIILGDSSVG KTSLMNQYVN KRFSNQYKAT IGADFCTKEV
60 70 80 90 100
VVNDRVVTMQ IWDTAGQERF QSLGVAFYRG ADCCVLVYDV TAPNSFKNLD
110 120 130 140 150
SWRDEFLIQA SPRDPDHFPF VVLGNKVDLD NRQVSTRRAQ QWCQSKNDIP
160 170 180 190 200
YYETSAKEGI NVEMAFQVIA KNALELEAEA EVINDFPDQI TLGSQNNRPG

NPDNCQC
Length:207
Mass (Da):23,331
Last modified:November 1, 1998 - v1
Checksum:iFFC76D3630287AEB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF079459 Genomic DNA Translation: AAC32270.1
AE014297 Genomic DNA Translation: AAF56218.1
AF263363 mRNA Translation: AAF73041.1
AY060236 mRNA Translation: AAL25275.1
BT124755 mRNA Translation: ADF28796.1
AE014297 Genomic DNA Translation: AFH06594.1
AE014297 Genomic DNA Translation: AFH06595.1
AB035672 mRNA Translation: BAA88245.1
AM294823 Genomic DNA Translation: CAL26809.1
AM294824 Genomic DNA Translation: CAL26810.1
AM294825 Genomic DNA Translation: CAL26811.1
AM294826 Genomic DNA Translation: CAL26812.1
AM294827 Genomic DNA Translation: CAL26813.1
AM294828 Genomic DNA Translation: CAL26814.1
AM294829 Genomic DNA Translation: CAL26815.1
AM294830 Genomic DNA Translation: CAL26816.1
AM294831 Genomic DNA Translation: CAL26817.1
AM294832 Genomic DNA Translation: CAL26818.1
AM294833 Genomic DNA Translation: CAL26819.1
FM245635 Genomic DNA Translation: CAR93561.1
FM245636 Genomic DNA Translation: CAR93562.1
FM245637 Genomic DNA Translation: CAR93563.1
FM245638 Genomic DNA Translation: CAR93564.1
FM245639 Genomic DNA Translation: CAR93565.1
FM245640 Genomic DNA Translation: CAR93566.1
FM245641 Genomic DNA Translation: CAR93567.1
FM245642 Genomic DNA Translation: CAR93568.1
FM245643 Genomic DNA Translation: CAR93569.1
FM245644 Genomic DNA Translation: CAR93570.1
FM245645 Genomic DNA Translation: CAR93571.1
RefSeqiNP_001247276.1, NM_001260347.1
NP_001247277.1, NM_001260348.2
NP_524472.1, NM_079748.4
UniGeneiDm.1701

Genome annotation databases

EnsemblMetazoaiFBtr0084503; FBpp0083891; FBgn0015795
FBtr0308611; FBpp0300835; FBgn0015795
FBtr0308612; FBpp0300836; FBgn0015795
GeneIDi42841
KEGGidme:Dmel_CG5915
UCSCiCG5915-RA d. melanogaster

Similar proteinsi

Entry informationi

Entry nameiO76742_DROME
AccessioniPrimary (citable) accession number: O76742
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1998
Last sequence update: November 1, 1998
Last modified: April 25, 2018
This is version 159 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported