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Protein
Submitted name:

TYRosinase

Gene

tyr-5

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Ligandi

Metal-bindingSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
TYRosinaseImported
Gene namesi
Name:tyr-5Imported
ORF Names:CELE_Y44E3B.2Imported, Y44E3B.2Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome I

Organism-specific databases

WormBaseiY44E3B.2; CE39838; WBGene00021553; tyr-5.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2121Sequence analysisAdd
BLAST
Chaini22 – 477456Sequence analysisPRO_5004160618Add
BLAST

Proteomic databases

PaxDbiO76708.
PRIDEiO76708.

Expressioni

Gene expression databases

BgeeiWBGene00021553.

Interactioni

Protein-protein interaction databases

STRINGi6239.Y44E3B.2.

Structurei

3D structure databases

ProteinModelPortaliO76708.
SMRiO76708. Positions 143-337.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini162 – 17918Tyrosinase_Cu-bdInterPro annotationAdd
BLAST

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410JA94. Eukaryota.
ENOG4111EAQ. LUCA.
GeneTreeiENSGT00510000050704.
HOGENOMiHOG000020483.
InParanoidiO76708.
OMAiSDERCFP.
OrthoDBiEOG091G03YR.

Family and domain databases

Gene3Di1.10.1280.10. 1 hit.
InterProiIPR002227. Tyrosinase_Cu-bd.
IPR008922. Unchr_di-copper_centre.
[Graphical view]
PfamiPF00264. Tyrosinase. 1 hit.
[Graphical view]
PRINTSiPR00092. TYROSINASE.
SUPFAMiSSF48056. SSF48056. 1 hit.
PROSITEiPS00497. TYROSINASE_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O76708-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVLILLLLLL LNGFLLEPVN SYVTVTKYTI GNKTYYEKFE QPWFRHMHYD
60 70 80 90 100
HDPVEASEKD ESAFGKHFVP EDDVFIAPDW TAHEAKYMSC LNRTCVCGYF
110 120 130 140 150
KGSVKNGECY LPSGKLLKRA VRRELRSLRP DDRIMIENAW NAMKKSGLYN
160 170 180 190 200
KIGRVHKYSG VHSGPAFTLW HREFLKRLEL ALRDHMKNPD FGLPFWDSTL
210 220 230 240 250
DSLLPEPKDS IIFSELFLGE VDDKGFVKNG PYHNWETMEG RAQIFRNFGE
260 270 280 290 300
DDSGEMLNDA RVDWLINNPD INMILGATMP LSTCPMNHTL DARMLEFSHD
310 320 330 340 350
YVHFFVNGDM SKSYSSSNDV CFVYHHGMID WIFEHWRQNM QSREERKTEY
360 370 380 390 400
PKSDERCFPF WHNGDNSMPL LQPLKNKDAL SNGYTDNMYE YYPRPTCTRE
410 420 430 440 450
NPDCDSPYLF CYIPPNNEHP PSCVSKVRRN GVCRGFEDYP ICYWGQCVDG
460 470
RCDETVKAPK RLEKFKKFEK KIVPFIM
Length:477
Mass (Da):55,862
Last modified:January 25, 2012 - v2
Checksum:i8DB16CC596EBD507
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284601 Genomic DNA. Translation: CCD73451.1.
RefSeqiNP_491131.2. NM_058730.2.
UniGeneiCel.28180.

Genome annotation databases

EnsemblMetazoaiY44E3B.2; Y44E3B.2; WBGene00021553.
GeneIDi189907.
KEGGicel:CELE_Y44E3B.2.
UCSCiY44E3B.2. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284601 Genomic DNA. Translation: CCD73451.1.
RefSeqiNP_491131.2. NM_058730.2.
UniGeneiCel.28180.

3D structure databases

ProteinModelPortaliO76708.
SMRiO76708. Positions 143-337.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi6239.Y44E3B.2.

Proteomic databases

PaxDbiO76708.
PRIDEiO76708.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiY44E3B.2; Y44E3B.2; WBGene00021553.
GeneIDi189907.
KEGGicel:CELE_Y44E3B.2.
UCSCiY44E3B.2. c. elegans.

Organism-specific databases

CTDi189907.
WormBaseiY44E3B.2; CE39838; WBGene00021553; tyr-5.

Phylogenomic databases

eggNOGiENOG410JA94. Eukaryota.
ENOG4111EAQ. LUCA.
GeneTreeiENSGT00510000050704.
HOGENOMiHOG000020483.
InParanoidiO76708.
OMAiSDERCFP.
OrthoDBiEOG091G03YR.

Gene expression databases

BgeeiWBGene00021553.

Family and domain databases

Gene3Di1.10.1280.10. 1 hit.
InterProiIPR002227. Tyrosinase_Cu-bd.
IPR008922. Unchr_di-copper_centre.
[Graphical view]
PfamiPF00264. Tyrosinase. 1 hit.
[Graphical view]
PRINTSiPR00092. TYROSINASE.
SUPFAMiSSF48056. SSF48056. 1 hit.
PROSITEiPS00497. TYROSINASE_1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiO76708_CAEEL
AccessioniPrimary (citable) accession number: O76708
Secondary accession number(s): G4SR48
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1998
Last sequence update: January 25, 2012
Last modified: September 7, 2016
This is version 95 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.