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Protein

Protein ver-2

Gene

ver-2

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

May be involved, downstream of pvf-1, in the positioning of ray 1, the most anterior ray sensillum in the male tail.1 Publication

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri446 – 49247ZZ-typePROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

GO - Biological processi

  • nematode male tail tip morphogenesis Source: WormBase
Complete GO annotation...

Keywords - Ligandi

Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Protein ver-2Curated
Alternative name(s):
Vascular endothelial growth factor receptor related 21 Publication
Gene namesi
Name:ver-2Imported
ORF Names:T17A3.8Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome III

Organism-specific databases

WormBaseiT17A3.8; CE31609; WBGene00006895; ver-2.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 518518Protein ver-2CuratedPRO_0000434514Add
BLAST

Proteomic databases

PaxDbiO76695.
PRIDEiO76695.

Expressioni

Tissue specificityi

Expressed in ADL neurons.1 Publication

Gene expression databases

BgeeiWBGene00006895.

Interactioni

Protein-protein interaction databases

STRINGi6239.T17A3.8.

Structurei

3D structure databases

ProteinModelPortaliO76695.
SMRiO76695. Positions 27-336.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini1 – 280280Protein kinasePROSITE-ProRule annotationAdd
BLAST

Domaini

The protein kinase domain is predicted to be catalytically inactive.PROSITE-ProRule annotation

Sequence similaritiesi

Belongs to the protein kinase superfamily. Tyr protein kinase family.PROSITE-ProRule annotation
Contains 1 protein kinase domain.PROSITE-ProRule annotation
Contains 1 ZZ-type zinc finger.PROSITE-ProRule annotation

Zinc finger

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri446 – 49247ZZ-typePROSITE-ProRule annotationAdd
BLAST

Keywords - Domaini

Zinc-finger

Phylogenomic databases

eggNOGiKOG0200. Eukaryota.
KOG4582. Eukaryota.
COG0515. LUCA.
ENOG410XYAV. LUCA.
GeneTreeiENSGT00830000128295.
InParanoidiO76695.
OrthoDBiEOG091G01TL.
PhylomeDBiO76695.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR001245. Ser-Thr/Tyr_kinase_cat_dom.
IPR008266. Tyr_kinase_AS.
IPR020635. Tyr_kinase_cat_dom.
IPR000433. Znf_ZZ.
[Graphical view]
PfamiPF07714. Pkinase_Tyr. 1 hit.
PF00569. ZZ. 1 hit.
[Graphical view]
PRINTSiPR00109. TYRKINASE.
SMARTiSM00219. TyrKc. 1 hit.
SM00291. ZnF_ZZ. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00109. PROTEIN_KINASE_TYR. 1 hit.
PS01357. ZF_ZZ_1. 1 hit.
PS50135. ZF_ZZ_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O76695-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSESLSTHTM NLPVEERTDF LSYNPKYEVD LEKLEILEQL GDGQFGLVNR
60 70 80 90 100
GLLQKVDPHS LIEYKIRLQV AVKRYGFLYV ITEYINGGDL LKYLRKLRSH
110 120 130 140 150
FKNELCNNDI VLHVSEKESC EKEELLVDAF DSLSTSDLLS IGLQIATGME
160 170 180 190 200
WLASVPCVHR DLACRNVLIT KTKIIRIADF GLTKIPTMSS EAIDDLKFTE
210 220 230 240 250
KSDVWSFGLC LYEIFTLGGT PYPNCGSIQE VIEFIENGNR NAQPKYCPDE
260 270 280 290 300
IYKLMKMCWK TSPKKRPTFK ECVKFFKNYM QEEVVQNIER KLQFEREEQQ
310 320 330 340 350
ELDSWTGKSL RAEGVEDKET EVLDKLMTLT KEEELEFIPQ ERRLDVLVNA
360 370 380 390 400
QKTICETKEK KGRIVFVTFA TKFDKKVVEI TLDEEDPLSQ LYKTAQEIFP
410 420 430 440 450
YFSWRFCLDE PTNLIEGLSN KRRVFGSIKQ SRFYNFLYLV ITLLPTYHPF
460 470 480 490 500
DCDECKAECN WNNRYKCTIC ADYDLCRQCE AKNLHANHAM LRILSSDTEL
510
PKYMYMSSPS FVSEHCSK
Length:518
Mass (Da):60,344
Last modified:October 1, 2002 - v2
Checksum:i631DAA3695DC86F8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284603 Genomic DNA. Translation: CCD66080.1.
PIRiT33431.
RefSeqiNP_497158.2. NM_064757.4.
UniGeneiCel.39284.

Genome annotation databases

EnsemblMetazoaiT17A3.8; T17A3.8; WBGene00006895.
GeneIDi188569.
KEGGicel:CELE_T17A3.8.
UCSCiT17A3.8. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284603 Genomic DNA. Translation: CCD66080.1.
PIRiT33431.
RefSeqiNP_497158.2. NM_064757.4.
UniGeneiCel.39284.

3D structure databases

ProteinModelPortaliO76695.
SMRiO76695. Positions 27-336.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi6239.T17A3.8.

Proteomic databases

PaxDbiO76695.
PRIDEiO76695.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiT17A3.8; T17A3.8; WBGene00006895.
GeneIDi188569.
KEGGicel:CELE_T17A3.8.
UCSCiT17A3.8. c. elegans.

Organism-specific databases

CTDi188569.
WormBaseiT17A3.8; CE31609; WBGene00006895; ver-2.

Phylogenomic databases

eggNOGiKOG0200. Eukaryota.
KOG4582. Eukaryota.
COG0515. LUCA.
ENOG410XYAV. LUCA.
GeneTreeiENSGT00830000128295.
InParanoidiO76695.
OrthoDBiEOG091G01TL.
PhylomeDBiO76695.

Miscellaneous databases

PROiO76695.

Gene expression databases

BgeeiWBGene00006895.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR001245. Ser-Thr/Tyr_kinase_cat_dom.
IPR008266. Tyr_kinase_AS.
IPR020635. Tyr_kinase_cat_dom.
IPR000433. Znf_ZZ.
[Graphical view]
PfamiPF07714. Pkinase_Tyr. 1 hit.
PF00569. ZZ. 1 hit.
[Graphical view]
PRINTSiPR00109. TYRKINASE.
SMARTiSM00219. TyrKc. 1 hit.
SM00291. ZnF_ZZ. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00109. PROTEIN_KINASE_TYR. 1 hit.
PS01357. ZF_ZZ_1. 1 hit.
PS50135. ZF_ZZ_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiVER2_CAEEL
AccessioniPrimary (citable) accession number: O76695
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 14, 2015
Last sequence update: October 1, 2002
Last modified: September 7, 2016
This is version 132 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.