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Protein
Submitted name:

Cysteinyl Amino-acyl tRNA Synthetase

Gene

cars-1

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetaseImported, Ligase

Names & Taxonomyi

Protein namesi
Submitted name:
Cysteinyl Amino-acyl tRNA SynthetaseImported
Gene namesi
Name:cars-1Imported
ORF Names:CELE_Y23H5A.7Imported, Y23H5A.7Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome I

Organism-specific databases

WormBaseiY23H5A.7a; CE18363; WBGene00000800; cars-1.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Proteomic databases

EPDiO76618.
PaxDbiO76618.
PRIDEiO76618.

Expressioni

Gene expression databases

BgeeiWBGene00000800.
ExpressionAtlasiO76618. baseline.

Interactioni

Protein-protein interaction databases

STRINGi6239.Y23H5A.7a.

Structurei

3D structure databases

ProteinModelPortaliO76618.
SMRiO76618. Positions 184-308, 371-612.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini198 – 614417tRNA-synt_1eInterPro annotationAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili819 – 85133Sequence analysisAdd
BLAST

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG2007. Eukaryota.
COG0215. LUCA.
GeneTreeiENSGT00390000006347.
HOGENOMiHOG000245252.
InParanoidiO76618.
OMAiFDILKLC.
OrthoDBiEOG091G03N1.
PhylomeDBiO76618.

Family and domain databases

CDDicd00672. CysRS_core. 1 hit.
Gene3Di3.40.50.620. 2 hits.
HAMAPiMF_00041. Cys_tRNA_synth. 1 hit.
InterProiIPR015803. Cys-tRNA-ligase.
IPR024909. Cys-tRNA/MSH_ligase.
IPR014729. Rossmann-like_a/b/a_fold.
IPR032678. tRNA-synt_1_cat_dom.
IPR009080. tRNAsynth_Ia_anticodon-bd.
[Graphical view]
PANTHERiPTHR10890. PTHR10890. 1 hit.
PfamiPF01406. tRNA-synt_1e. 1 hit.
[Graphical view]
PRINTSiPR00983. TRNASYNTHCYS.
SUPFAMiSSF47323. SSF47323. 1 hit.
TIGRFAMsiTIGR00435. cysS. 1 hit.

Sequencei

Sequence statusi: Complete.

O76618-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHLKNIFCYE KSKKNRNFKK KPFFGCGFLN LKRFLICLNV KFLGKQHFIR
60 70 80 90 100
FSISPHPFIR SNSSKYIYSP FIFCHRTANS CVAVCSLFTC LHSLVLLLHS
110 120 130 140 150
SKTTAFLGVF VRKFGTTRSK NLVRVLLFAS FNRNQTQLFA WNCSKLQLRS
160 170 180 190 200
HHHCIMDPNL RPVAVKRVQK HWDQPKNATP PPQLTVYNSL TRQKEVFVPN
210 220 230 240 250
EGKRVRWYIC GPTVYDSSHM GHARSYLSLD ILRRVFRDYF GYDVEFIMNI
260 270 280 290 300
TDVDDKIIKR ARQSHLLKSY FNESQAPPVM KVCEDVVAAL EHFKTKFETE
310 320 330 340 350
MDPDKKKMFE VMIKKVQQQS SALEEAMKAQ DSIATEEAKG RLLNESRDVL
360 370 380 390 400
SEWLDHNHGK DVRDHSVFDD LAKTYEKEFL ADMARLNVLP VDVLTRVSEY
410 420 430 440 450
VPEVITYVKK IISNGYAYAA EDGSVYFDTK AFEQNPKHFY AKLVPEAYGE
460 470 480 490 500
DSEQLLKNMK ESEGELSMSD DRLKSKRSPN DFALWKSSKD GEPFWPSEWG
510 520 530 540 550
NGRPGWHIEC SVMSSAICGS KLDIHAGGFD LKFPHHDNEI AQVEAHYDDP
560 570 580 590 600
HWVNYFLHCG TLRIQGMKMS KSLKNFITIR KALEDYTPRQ LRLLFLMHNW
610 620 630 640 650
ADVLDYSSST MERALQFEKI TNEFFLLVKD FLRRHYKPDR SEGYQKFQGK
660 670 680 690 700
ELKLMEEFGK LKSEVHEALC DSVDTRSVIE KFRELISLGN AYIVEKEKEG
710 720 730 740 750
HVPNCLLLRN IAAYITNLLK IFGAIPQSNQ EIGFVSEDEC NGEGASTSFN
760 770 780 790 800
KEAVVMPYLD ALAQFREKVR LIAKEHKVNG ILEECDTLRD KTLTELGVRL
810 820 830 840 850
EDRNGQTVVK LVDRATLLRE QEQKDTEKKR KDKEKADKEQ KAREKADKEA
860 870 880 890 900
AAKKIKPEEL FKQGEHVGKY SKFDERGVPT HLADGTEITK SQIKKLEKVY

EAQKKKYQQ
Length:909
Mass (Da):105,317
Last modified:November 1, 1998 - v1
Checksum:iFDF4E96133864DAC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284601 Genomic DNA. Translation: CCD70915.1.
PIRiH87729.
RefSeqiNP_491013.1. NM_058612.1.
UniGeneiCel.6428.

Genome annotation databases

EnsemblMetazoaiY23H5A.7a; Y23H5A.7a; WBGene00000800.
GeneIDi171821.
UCSCiY23H5A.7b. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284601 Genomic DNA. Translation: CCD70915.1.
PIRiH87729.
RefSeqiNP_491013.1. NM_058612.1.
UniGeneiCel.6428.

3D structure databases

ProteinModelPortaliO76618.
SMRiO76618. Positions 184-308, 371-612.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi6239.Y23H5A.7a.

Proteomic databases

EPDiO76618.
PaxDbiO76618.
PRIDEiO76618.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiY23H5A.7a; Y23H5A.7a; WBGene00000800.
GeneIDi171821.
UCSCiY23H5A.7b. c. elegans.

Organism-specific databases

CTDi171821.
WormBaseiY23H5A.7a; CE18363; WBGene00000800; cars-1.

Phylogenomic databases

eggNOGiKOG2007. Eukaryota.
COG0215. LUCA.
GeneTreeiENSGT00390000006347.
HOGENOMiHOG000245252.
InParanoidiO76618.
OMAiFDILKLC.
OrthoDBiEOG091G03N1.
PhylomeDBiO76618.

Gene expression databases

BgeeiWBGene00000800.
ExpressionAtlasiO76618. baseline.

Family and domain databases

CDDicd00672. CysRS_core. 1 hit.
Gene3Di3.40.50.620. 2 hits.
HAMAPiMF_00041. Cys_tRNA_synth. 1 hit.
InterProiIPR015803. Cys-tRNA-ligase.
IPR024909. Cys-tRNA/MSH_ligase.
IPR014729. Rossmann-like_a/b/a_fold.
IPR032678. tRNA-synt_1_cat_dom.
IPR009080. tRNAsynth_Ia_anticodon-bd.
[Graphical view]
PANTHERiPTHR10890. PTHR10890. 1 hit.
PfamiPF01406. tRNA-synt_1e. 1 hit.
[Graphical view]
PRINTSiPR00983. TRNASYNTHCYS.
SUPFAMiSSF47323. SSF47323. 1 hit.
TIGRFAMsiTIGR00435. cysS. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiO76618_CAEEL
AccessioniPrimary (citable) accession number: O76618
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1998
Last sequence update: November 1, 1998
Last modified: September 7, 2016
This is version 123 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.