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Protein

Probable peptidyl-tRNA hydrolase 2

Gene

C24G6.8

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.By similarity

Catalytic activityi

N-substituted aminoacyl-tRNA + H2O = N-substituted amino acid + tRNA.

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase

Enzyme and pathway databases

ReactomeiR-CEL-5689880 Ub-specific processing proteases

Names & Taxonomyi

Protein namesi
Recommended name:
Probable peptidyl-tRNA hydrolase 2 (EC:3.1.1.29)
Short name:
PTH 2
Gene namesi
ORF Names:C24G6.8
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome V

Organism-specific databases

WormBaseiC24G6.8b ; CE17464 ; WBGene00016062

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001202831 – 316Probable peptidyl-tRNA hydrolase 2Add BLAST316

Proteomic databases

EPDiO76387
PaxDbiO76387
PeptideAtlasiO76387
PRIDEiO76387

PTM databases

iPTMnetiO76387

Expressioni

Gene expression databases

BgeeiWBGene00016062

Interactioni

Protein-protein interaction databases

DIPiDIP-59880N
IntActiO76387 2 interactors.
STRINGi6239.C24G6.8.4

Structurei

3D structure databases

ProteinModelPortaliO76387
SMRiO76387
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini128 – 169UBAPROSITE-ProRule annotationAdd BLAST42

Sequence similaritiesi

Belongs to the PTH2 family.Curated

Phylogenomic databases

eggNOGiKOG3282 Eukaryota
COG1990 LUCA
GeneTreeiENSGT00390000015991
HOGENOMiHOG000018975
InParanoidiO76387
KOiK04794
OMAiNNEYLAH
OrthoDBiEOG091G0WC2
PhylomeDBiO76387

Family and domain databases

CDDicd02430 PTH2, 1 hit
Gene3Di3.40.1490.101 hit
InterProiView protein in InterPro
IPR023476 Pep_tRNA_hydro_II_dom_sf
IPR002833 PTH2
IPR015940 UBA
IPR009060 UBA-like_sf
PfamiView protein in Pfam
PF01981 PTH2, 1 hit
PF00627 UBA, 1 hit
SUPFAMiSSF102462 SSF102462, 1 hit
SSF46934 SSF46934, 1 hit
TIGRFAMsiTIGR00283 arch_pth2, 1 hit
PROSITEiView protein in PROSITE
PS50030 UBA, 1 hit

Sequencei

Sequence statusi: Complete.

O76387-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSENIPDIDP NELLPNAPGQ HQDLGVDNPP EPDNASIRAE RGSPTPSSVT
60 70 80 90 100
VDNAPSLPDR SFSHLPINDP FSGEIPEVPI PSSAISISSQ ALSDPVPTPS
110 120 130 140 150
DTSRPGILRN DEQGSTSSHP VDPQEPNEVN NEYLAHLLDL GFDEYTAVLA
160 170 180 190 200
LKRTNSAGVE QAVAWIVERS NESDFDEDSS SSENEADEEM GAVQSVAGRT
210 220 230 240 250
HKMVLVANMS LKMGTGKIAA QVGHATLGVY RQAMNSENGQ NAIAAWTRHG
260 270 280 290 300
QVKIVVKGQS TEQLMDLCKV AKDAGCYYYL VQDAGYTQIP AGSRTVLGIF
310
GTVEQVDSVT GGLKLL
Length:316
Mass (Da):33,689
Last modified:November 1, 1998 - v1
Checksum:i20E4FA3D52B4EFB0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FO080610 Genomic DNA Translation: CCD65135.1
PIRiT33180
RefSeqiNP_504461.1, NM_072060.4
UniGeneiCel.6598

Genome annotation databases

EnsemblMetazoaiC24G6.8b.1; C24G6.8b.1; WBGene00016062
C24G6.8b.2; C24G6.8b.2; WBGene00016062
C24G6.8b.3; C24G6.8b.3; WBGene00016062
GeneIDi178937
KEGGicel:CELE_C24G6.8
UCSCiC24G6.8.1 c. elegans

Similar proteinsi

Entry informationi

Entry nameiPTH2_CAEEL
AccessioniPrimary (citable) accession number: O76387
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: November 1, 1998
Last modified: February 28, 2018
This is version 113 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome