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Protein

Probable peptidyl-tRNA hydrolase 2

Gene

C24G6.8

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.By similarity

Catalytic activityi

N-substituted aminoacyl-tRNA + H2O = N-substituted amino acid + tRNA.

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
Probable peptidyl-tRNA hydrolase 2 (EC:3.1.1.29)
Short name:
PTH 2
Gene namesi
ORF Names:C24G6.8
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome V

Organism-specific databases

WormBaseiC24G6.8; CE17464; WBGene00016062.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001202831 – 316Probable peptidyl-tRNA hydrolase 2Add BLAST316

Proteomic databases

EPDiO76387.
PaxDbiO76387.
PeptideAtlasiO76387.
PRIDEiO76387.

PTM databases

iPTMnetiO76387.

Expressioni

Gene expression databases

BgeeiWBGene00016062.

Interactioni

Protein-protein interaction databases

DIPiDIP-59880N.
IntActiO76387. 1 interactor.
STRINGi6239.C24G6.8.4.

Structurei

3D structure databases

ProteinModelPortaliO76387.
SMRiO76387.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini128 – 169UBAPROSITE-ProRule annotationAdd BLAST42

Sequence similaritiesi

Belongs to the PTH2 family.Curated

Phylogenomic databases

eggNOGiKOG3282. Eukaryota.
COG1990. LUCA.
GeneTreeiENSGT00390000015991.
HOGENOMiHOG000018975.
InParanoidiO76387.
KOiK04794.
OMAiNNEYLAH.
OrthoDBiEOG091G0WC2.
PhylomeDBiO76387.

Family and domain databases

CDDicd02430. PTH2. 1 hit.
Gene3Di3.40.1490.10. 1 hit.
InterProiView protein in InterPro
IPR023476. Pep_tRNA_hydro_II_dom.
IPR002833. PTH2.
IPR015940. UBA.
IPR009060. UBA-like.
PfamiView protein in Pfam
PF01981. PTH2. 1 hit.
PF00627. UBA. 1 hit.
SUPFAMiSSF102462. SSF102462. 1 hit.
SSF46934. SSF46934. 1 hit.
TIGRFAMsiTIGR00283. arch_pth2. 1 hit.
PROSITEiView protein in PROSITE
PS50030. UBA. 1 hit.

Sequencei

Sequence statusi: Complete.

O76387-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSENIPDIDP NELLPNAPGQ HQDLGVDNPP EPDNASIRAE RGSPTPSSVT
60 70 80 90 100
VDNAPSLPDR SFSHLPINDP FSGEIPEVPI PSSAISISSQ ALSDPVPTPS
110 120 130 140 150
DTSRPGILRN DEQGSTSSHP VDPQEPNEVN NEYLAHLLDL GFDEYTAVLA
160 170 180 190 200
LKRTNSAGVE QAVAWIVERS NESDFDEDSS SSENEADEEM GAVQSVAGRT
210 220 230 240 250
HKMVLVANMS LKMGTGKIAA QVGHATLGVY RQAMNSENGQ NAIAAWTRHG
260 270 280 290 300
QVKIVVKGQS TEQLMDLCKV AKDAGCYYYL VQDAGYTQIP AGSRTVLGIF
310
GTVEQVDSVT GGLKLL
Length:316
Mass (Da):33,689
Last modified:November 1, 1998 - v1
Checksum:i20E4FA3D52B4EFB0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FO080610 Genomic DNA. Translation: CCD65135.1.
PIRiT33180.
RefSeqiNP_504461.1. NM_072060.4.
UniGeneiCel.6598.

Genome annotation databases

EnsemblMetazoaiC24G6.8.1; C24G6.8.1; WBGene00016062.
C24G6.8.2; C24G6.8.2; WBGene00016062.
C24G6.8.3; C24G6.8.3; WBGene00016062.
C24G6.8.4; C24G6.8.4; WBGene00016062.
GeneIDi178937.
KEGGicel:CELE_C24G6.8.
UCSCiC24G6.8.1. c. elegans.

Similar proteinsi

Entry informationi

Entry nameiPTH2_CAEEL
AccessioniPrimary (citable) accession number: O76387
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: November 1, 1998
Last modified: August 30, 2017
This is version 109 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  2. SIMILARITY comments
    Index of protein domains and families