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Protein
Submitted name:

Proteasome Regulatory Particle, ATPase-like

Gene

rpt-5

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandATP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-CEL-1234176. Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha.
R-CEL-1236978. Cross-presentation of soluble exogenous antigens (endosomes).
R-CEL-195253. Degradation of beta-catenin by the destruction complex.
R-CEL-382556. ABC-family proteins mediated transport.
R-CEL-4608870. Asymmetric localization of PCP proteins.
R-CEL-4641258. Degradation of DVL.
R-CEL-5632684. Hedgehog 'on' state.
R-CEL-5689603. UCH proteinases.
R-CEL-5689880. Ub-specific processing proteases.
R-CEL-6798695. Neutrophil degranulation.
R-CEL-68949. Orc1 removal from chromatin.
R-CEL-69229. Ubiquitin-dependent degradation of Cyclin D1.
R-CEL-69601. Ubiquitin Mediated Degradation of Phosphorylated Cdc25A.
R-CEL-8941858. Regulation of RUNX3 expression and activity.
R-CEL-983168. Antigen processing: Ubiquitination & Proteasome degradation.

Names & Taxonomyi

Protein namesi
Submitted name:
Proteasome Regulatory Particle, ATPase-likeImported
Gene namesi
Name:rpt-5Imported
ORF Names:CELE_F56H1.4Imported, F56H1.4Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome I

Organism-specific databases

WormBaseiF56H1.4; CE17915; WBGene00004505; rpt-5.

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

ProteasomeImported

PTM / Processingi

Proteomic databases

EPDiO76371.
PaxDbiO76371.
PeptideAtlasiO76371.

Expressioni

Gene expression databases

BgeeiWBGene00004505.

Interactioni

Binary interactionsi

Show more details

GO - Molecular functioni

Protein-protein interaction databases

IntActiO76371. 4 interactors.
MINTiMINT-211164.
STRINGi6239.F56H1.4.2.

Structurei

3D structure databases

ProteinModelPortaliO76371.
SMRiO76371.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini210 – 349AAAInterPro annotationAdd BLAST140

Sequence similaritiesi

Belongs to the AAA ATPase family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0652. Eukaryota.
COG1222. LUCA.
GeneTreeiENSGT00730000111070.
HOGENOMiHOG000225143.
InParanoidiO76371.
KOiK03065.
OMAiRACAAQS.
OrthoDBiEOG091G07E0.
PhylomeDBiO76371.

Family and domain databases

InterProiView protein in InterPro
IPR005937. 26S_Psome_P45.
IPR003593. AAA+_ATPase.
IPR003959. ATPase_AAA_core.
IPR003960. ATPase_AAA_CS.
IPR027417. P-loop_NTPase.
PfamiView protein in Pfam
PF00004. AAA. 1 hit.
SMARTiView protein in SMART
SM00382. AAA. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR01242. 26Sp45. 1 hit.
PROSITEiView protein in PROSITE
PS00674. AAA. 1 hit.

Sequencei

Sequence statusi: Complete.

O76371-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSQTPPPKDG KNPEAMEVED AIDEEILKMS TEDLKSRTHL LDNEIRIMRS
60 70 80 90 100
EVQRINHSAT TLKERIKENT ERIKVNKTLP YLVSNVVELL DLEDNTEEEG
110 120 130 140 150
ANVDLDAQKT KCAVIKTSTR ATYFLPVVGL VDPDELKPGD LVGVNKDSYL
160 170 180 190 200
ILEKLPAEYD SRVKAMEVDE RPTEQYSDIG GCDKQIQELI EAVVLPMTHK
210 220 230 240 250
DRFVNLGIHP PKGVLMYGPP GTGKTMMARA VAAQTKSTFL KLAGPQLVQM
260 270 280 290 300
FIGDGAKLVR DAFALAKEKA PAIIFIDELD AIGTKRFDSE KAGDREVQRT
310 320 330 340 350
MLELLNQLDG FQPNDDIKVI AATNRIDVLD PALLRSGRLD RKIELPHPNE
360 370 380 390 400
DARARIMQIH SRKMNVNKDV NFEELARCTD DFNGAQCKAV CVEAGMIALR
410 420 430
RDATEILHED FMDAILEVQA KKKASLNYYA
Length:430
Mass (Da):48,126
Last modified:November 1, 1998 - v1
Checksum:i1B6DAA1E8E40E3EC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284601 Genomic DNA. Translation: CCD62966.1.
PIRiT33155.
RefSeqiNP_491672.1. NM_059271.3.
UniGeneiCel.136.

Genome annotation databases

EnsemblMetazoaiF56H1.4; F56H1.4; WBGene00004505.
GeneIDi172238.
KEGGicel:CELE_F56H1.4.
UCSCiF56H1.4.2. c. elegans.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiO76371_CAEEL
AccessioniPrimary (citable) accession number: O76371
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1998
Last sequence update: November 1, 1998
Last modified: June 7, 2017
This is version 146 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported