Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Neural hemoglobin

Gene
N/A
Organism
Cerebratulus lacteus (Milky ribbon worm) (Micrura lactea)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Acts as an oxygen store capable of sustaining neuronal activity in an anoxic environment for 5 to 30 min.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi70Iron (heme proximal ligand)1

GO - Molecular functioni

Complete GO annotation...

Keywords - Biological processi

Oxygen transport, Transport

Keywords - Ligandi

Heme, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Neural hemoglobin
Short name:
NrHb
OrganismiCerebratulus lacteus (Milky ribbon worm) (Micrura lactea)
Taxonomic identifieri6221 [NCBI]
Taxonomic lineageiEukaryotaMetazoaLophotrochozoaNemerteaAnoplaHeteronemerteaCerebratulidaeCerebratulus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemoved1 Publication
ChainiPRO_00000524992 – 110Neural hemoglobinAdd BLAST109

Interactioni

Subunit structurei

Homotetramer. Self-associates in the deoxy state. Seems to dissociate upon oxygenation.1 Publication

Structurei

Secondary structure

1110
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi4 – 18Combined sources15
Helixi20 – 25Combined sources6
Turni27 – 30Combined sources4
Helixi33 – 38Combined sources6
Helixi40 – 58Combined sources19
Helixi63 – 71Combined sources9
Turni72 – 74Combined sources3
Helixi77 – 93Combined sources17
Helixi100 – 107Combined sources8

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1KR7X-ray1.50A1-110[»]
1V07X-ray1.70A2-110[»]
2VYYX-ray1.60A1-110[»]
2VYZX-ray1.80A1-110[»]
2XKGX-ray1.60A1-110[»]
2XKHX-ray2.31A1-110[»]
2XKIX-ray1.30A1-110[»]
4AVDX-ray1.50A1-110[»]
4AVEX-ray1.90A1-110[»]
4F68X-ray1.80A1-110[»]
4F69X-ray1.60A1-110[»]
4F6BX-ray1.64A1-110[»]
4F6DX-ray1.80A1-110[»]
4F6FX-ray1.56A1-110[»]
4F6GX-ray1.64A1-110[»]
4F6IX-ray1.56A1-110[»]
4F6JX-ray1.45A1-110[»]
ProteinModelPortaliO76242.
SMRiO76242.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiO76242.

Family & Domainsi

Sequence similaritiesi

Belongs to the globin family.Curated

Family and domain databases

Gene3Di1.10.490.10. 1 hit.
InterProiIPR000971. Globin.
IPR009050. Globin-like.
IPR012292. Globin/Proto.
[Graphical view]
PfamiPF00042. Globin. 1 hit.
[Graphical view]
SUPFAMiSSF46458. SSF46458. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

O76242-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVNWAAVVDD FYQELFKAHP EYQNKFGFKG VALGSLKGNA AYKTQAGKTV
60 70 80 90 100
DYINAAIGGS ADAAGLASRH KGRNVGSAEF HNAKACLAKA CSAHGAPDLG
110
HAIDDILSHL
Length:110
Mass (Da):11,530
Last modified:January 23, 2007 - v3
Checksum:i0F30C4420773F244
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF033001 Genomic DNA. Translation: AAC39125.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF033001 Genomic DNA. Translation: AAC39125.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1KR7X-ray1.50A1-110[»]
1V07X-ray1.70A2-110[»]
2VYYX-ray1.60A1-110[»]
2VYZX-ray1.80A1-110[»]
2XKGX-ray1.60A1-110[»]
2XKHX-ray2.31A1-110[»]
2XKIX-ray1.30A1-110[»]
4AVDX-ray1.50A1-110[»]
4AVEX-ray1.90A1-110[»]
4F68X-ray1.80A1-110[»]
4F69X-ray1.60A1-110[»]
4F6BX-ray1.64A1-110[»]
4F6DX-ray1.80A1-110[»]
4F6FX-ray1.56A1-110[»]
4F6GX-ray1.64A1-110[»]
4F6IX-ray1.56A1-110[»]
4F6JX-ray1.45A1-110[»]
ProteinModelPortaliO76242.
SMRiO76242.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Miscellaneous databases

EvolutionaryTraceiO76242.

Family and domain databases

Gene3Di1.10.490.10. 1 hit.
InterProiIPR000971. Globin.
IPR009050. Globin-like.
IPR012292. Globin/Proto.
[Graphical view]
PfamiPF00042. Globin. 1 hit.
[Graphical view]
SUPFAMiSSF46458. SSF46458. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiGLBN_CERLA
AccessioniPrimary (citable) accession number: O76242
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 10, 2002
Last sequence update: January 23, 2007
Last modified: November 2, 2016
This is version 85 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

3D-structure, Direct protein sequencing

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.