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Protein

Ras-related protein Rab-1C

Gene

Rab1C

Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi40 – 489GTPBy similarity
Nucleotide bindingi58 – 658GTPBy similarity
Nucleotide bindingi88 – 925GTPBy similarity
Nucleotide bindingi146 – 1494GTPBy similarity
Nucleotide bindingi176 – 1783GTPBy similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Ligandi

GTP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Ras-related protein Rab-1C
Gene namesi
Name:Rab1C
ORF Names:DDB_G0269174
OrganismiDictyostelium discoideum (Slime mold)
Taxonomic identifieri44689 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium
Proteomesi
  • UP000002195 Componentsi: Chromosome 1, Unassembled WGS sequence

Organism-specific databases

dictyBaseiDDB_G0269174. rab1C.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methionineiRemovedSequence analysis
Chaini2 – 201200Ras-related protein Rab-1CPRO_0000332748Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Lipidationi2 – 21N-myristoyl glycineSequence analysis
Lipidationi3 – 31S-palmitoyl cysteineSequence analysis

Post-translational modificationi

Although this sequence lacks the C-terminal cysteine motifs subject to isoprenylation in other Rab proteins, it does have N-terminal myristoylation and S-palmitoylation sequence motifs.

Keywords - PTMi

Lipoprotein, Myristate, Palmitate

Proteomic databases

PaxDbiO76173.
PRIDEiO76173.

Interactioni

Protein-protein interaction databases

STRINGi44689.DDB0191203.

Structurei

3D structure databases

ProteinModelPortaliO76173.
SMRiO76173. Positions 29-201.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi62 – 709Effector regionBy similarity

Sequence similaritiesi

Belongs to the small GTPase superfamily. Rab family.Curated

Phylogenomic databases

eggNOGiKOG0084. Eukaryota.
ENOG410XQN5. LUCA.
InParanoidiO76173.
OMAiFCIRTIE.
PhylomeDBiO76173.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR001806. Small_GTPase.
[Graphical view]
PfamiPF00071. Ras. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00231. small_GTP. 1 hit.
PROSITEiPS51419. RAB. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

O76173-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGCSPSKEGN GSFSSTSTSF IHGSESHPEY DMLLKILVIG DSGVGKSCML
60 70 80 90 100
LRFADNRFTD SYISTIGVDF CIRTIELDGK KIKLQIWDTA GQERFKTITT
110 120 130 140 150
SYYRGAHGLI IVYDITSMDS FNSIKRWLID VDRFASPSVL KLIVGNKCDL
160 170 180 190 200
NSKRAVDFKI AKKFADELNI PIMETSAKES TAIDEAFIKL ASDIKKSTPQ

K
Length:201
Mass (Da):22,343
Last modified:November 1, 1998 - v1
Checksum:i881FC10CC7DCA4D4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB015237 mRNA. Translation: BAA31150.1.
AAFI02000005 Genomic DNA. Translation: EAL71937.1.
RefSeqiXP_646027.1. XM_640935.1.

Genome annotation databases

EnsemblProtistsiDDB0191203; DDB0191203; DDB_G0269174.
GeneIDi8616975.
KEGGiddi:DDB_G0269174.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB015237 mRNA. Translation: BAA31150.1.
AAFI02000005 Genomic DNA. Translation: EAL71937.1.
RefSeqiXP_646027.1. XM_640935.1.

3D structure databases

ProteinModelPortaliO76173.
SMRiO76173. Positions 29-201.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi44689.DDB0191203.

Proteomic databases

PaxDbiO76173.
PRIDEiO76173.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsiDDB0191203; DDB0191203; DDB_G0269174.
GeneIDi8616975.
KEGGiddi:DDB_G0269174.

Organism-specific databases

dictyBaseiDDB_G0269174. rab1C.

Phylogenomic databases

eggNOGiKOG0084. Eukaryota.
ENOG410XQN5. LUCA.
InParanoidiO76173.
OMAiFCIRTIE.
PhylomeDBiO76173.

Miscellaneous databases

PROiO76173.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR001806. Small_GTPase.
[Graphical view]
PfamiPF00071. Ras. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00231. small_GTP. 1 hit.
PROSITEiPS51419. RAB. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRAB1C_DICDI
AccessioniPrimary (citable) accession number: O76173
Secondary accession number(s): Q55DV4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 29, 2008
Last sequence update: November 1, 1998
Last modified: July 6, 2016
This is version 99 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Dictyostelium discoideum
    Dictyostelium discoideum: entries, gene names and cross-references to dictyBase
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.