O76068 (O76068_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Peripheral-type benzodiazepine receptor EMBL AAC31173.1

Gene names

Name:

PBR EMBL AAC31173.1

Organism

Homo sapiens (Human) EMBL AAC31173.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	143 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Molecular function	Receptor EMBL AAC31173.1
Gene Ontology (GO)
Biological_process	adrenal gland development Inferred from electronic annotation. Source: Compara aging Inferred from electronic annotation. Source: Compara behavioral response to pain Inferred from electronic annotation. Source: Compara cellular hypotonic response Inferred from electronic annotation. Source: Compara cellular response to lipopolysaccharide Inferred from electronic annotation. Source: Compara cellular response to zinc ion Inferred from electronic annotation. Source: Compara contact inhibition Inferred from electronic annotation. Source: Compara glial cell migration Inferred from electronic annotation. Source: Compara negative regulation of glial cell proliferation Inferred from electronic annotation. Source: Compara negative regulation of nitric oxide biosynthetic process Inferred from electronic annotation. Source: Compara negative regulation of tumor necrosis factor production Inferred from electronic annotation. Source: Compara peripheral nervous system axon regeneration Inferred from electronic annotation. Source: Compara positive regulation of apoptotic process Inferred from electronic annotation. Source: Compara positive regulation of calcium ion transport Inferred from electronic annotation. Source: Compara positive regulation of glial cell proliferation Inferred from electronic annotation. Source: Compara positive regulation of mitochondrial depolarization Inferred from electronic annotation. Source: Compara positive regulation of necrotic cell death Inferred from electronic annotation. Source: Compara positive regulation of reactive oxygen species metabolic process Inferred from electronic annotation. Source: Compara regulation of steroid biosynthetic process Inferred from electronic annotation. Source: Compara response to drug Inferred from electronic annotation. Source: Compara response to manganese ion Inferred from electronic annotation. Source: Compara response to progesterone stimulus Inferred from electronic annotation. Source: Compara response to testosterone stimulus Inferred from electronic annotation. Source: Compara response to vitamin B1 Inferred from electronic annotation. Source: Compara steroid biosynthetic process Inferred from electronic annotation. Source: Compara
Cellular_component	integral to membrane Inferred from electronic annotation. Source: InterPro mitochondrial outer membrane Inferred from electronic annotation. Source: Compara
Molecular_function	androgen binding Inferred from electronic annotation. Source: Compara benzodiazepine receptor activity Inferred from electronic annotation. Source: Compara
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL AAC31173.1

Sequences

	Sequence		Length	Mass (Da)
	O76068 [UniParc]. Last modified November 1, 1998. Version 1. Checksum: DEAF74A8415C65A9	FASTA	143	16,107
	10 20 30 40 50 60 HGEGLRWYAG LQKPSWHPPH WVLGPVWGTL YSAMGYGSYL VWKELGGFTE KAVVPLGLYT 70 80 90 100 110 120 GQLALNWAWP PIFFGARQMG WALVDLLLVS GAAAATTVAW YQVSPLAARL LYPYLAWLAF 130 140 TTTLNYCVWR DNHGWRGGRR LPE

References

[1]	"Peripheral-type Benzodiazepine Receptor (PBR) in Human Breast Cancer." Hardwick M.J., Papadopoulos V. Submitted (JUN-1998) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Breast EMBL AAC31173.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF075589 mRNA. Translation: AAC31172.1. AF075590 mRNA. Translation: AAC31173.1.
IPI	IPI00026850.
RefSeq	NP_000705.2. NM_000714.5. NP_001243459.1. NM_001256530.1. NP_001243460.1. NM_001256531.1.
UniGene	Hs.202.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	O76068.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	706.
KEGG	hsa:706.
Organism-specific databases
CTD	706.
Phylogenomic databases
HOVERGEN	HBG001296.
KO	K05770.
Gene expression databases
ArrayExpress	O76068.
Bgee	O76068.
Family and domain databases
InterPro	IPR004307. TspO_MBR. [Graphical view]
PANTHER	PTHR10057. PTHR10057. 1 hit.
Pfam	PF03073. TspO_MBR. 1 hit. [Graphical view]
PIRSF	PIRSF005859. PBR. 1 hit.
ProtoNet	Search...
Other
ChiTaRS	TSPO. human.
GenomeRNAi	706.
NextBio	2874.

Entry information

Entry name

O76068_HUMAN

Accession

Primary (citable) accession number: O76068

Entry history

Integrated into UniProtKB/TrEMBL:	November 1, 1998
Last sequence update:	November 1, 1998
Last modified:	April 3, 2013
This is version 50 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.