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Protein
Submitted name:

Peripheral-type benzodiazepine receptor

Gene

PBR

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

Keywordsi

Molecular functionReceptorImported

Names & Taxonomyi

Protein namesi
Submitted name:
Peripheral-type benzodiazepine receptorImported
Gene namesi
Name:PBRImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei21 – 40HelicalSequence analysisAdd BLAST20
Transmembranei52 – 69HelicalSequence analysisAdd BLAST18
Transmembranei81 – 103HelicalSequence analysisAdd BLAST23
Transmembranei109 – 129HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG3797. Eukaryota.
COG3476. LUCA.
HOVERGENiHBG001296.
KOiK05770.

Family and domain databases

CDDicd15904. TSPO_MBR. 1 hit.
InterProiView protein in InterPro
IPR030164. TSPO.
IPR004307. TspO_MBR.
PANTHERiPTHR10057. PTHR10057. 1 hit.
PTHR10057:SF5. PTHR10057:SF5. 1 hit.
PfamiView protein in Pfam
PF03073. TspO_MBR. 1 hit.
PIRSFiPIRSF005859. PBR. 1 hit.

Sequencei

Sequence statusi: Fragment.

O76068-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
HGEGLRWYAG LQKPSWHPPH WVLGPVWGTL YSAMGYGSYL VWKELGGFTE
60 70 80 90 100
KAVVPLGLYT GQLALNWAWP PIFFGARQMG WALVDLLLVS GAAAATTVAW
110 120 130 140
YQVSPLAARL LYPYLAWLAF TTTLNYCVWR DNHGWRGGRR LPE
Length:143
Mass (Da):16,107
Last modified:November 1, 1998 - v1
Checksum:iDEAF74A8415C65A9
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF075589 mRNA. Translation: AAC31172.1.
AF075590 mRNA. Translation: AAC31173.1.
RefSeqiNP_000705.2. NM_000714.5.
NP_001243459.1. NM_001256530.1.
NP_001243460.1. NM_001256531.1.
UniGeneiHs.202.

Genome annotation databases

GeneIDi706.
KEGGihsa:706.

Similar proteinsi

Entry informationi

Entry nameiO76068_HUMAN
AccessioniPrimary (citable) accession number: O76068
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1998
Last sequence update: November 1, 1998
Last modified: October 25, 2017
This is version 77 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.