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O75889

- O75889_HUMAN

UniProt

O75889 - O75889_HUMAN

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Protein
Submitted name:

Killer cell lectin-like receptor subfamily A, member 1

Gene

LY49L

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. carbohydrate binding Source: ProtInc
  2. transmembrane signaling receptor activity Source: ProtInc

GO - Biological processi

  1. cell surface receptor signaling pathway Source: ProtInc
Complete GO annotation...

Keywords - Molecular functioni

ReceptorImported

Keywords - Ligandi

LectinImported

Names & Taxonomyi

Protein namesi
Submitted name:
Killer cell lectin-like receptor subfamily A, member 1Imported
Submitted name:
Killer cell lectin-like receptor subfamily A, member 1, isoform CRA_aImported
Submitted name:
Ly-49LImported
Gene namesi
Name:LY49LImported
Synonyms:KLRA1Imported
ORF Names:hCG_27420Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. plasma membrane Source: ProtInc
Complete GO annotation...

Interactioni

Protein-protein interaction databases

IntActiO75889. 1 interaction.
STRINGi9606.ENSP00000023165.

Structurei

3D structure databases

ProteinModelPortaliO75889.
SMRiO75889. Positions 157-197.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOVERGENiHBG053176.

Family and domain databases

Gene3Di3.10.100.10. 1 hit.
InterProiIPR016186. C-type_lectin-like.
IPR016187. C-type_lectin_fold.
IPR013600. Ly49.
[Graphical view]
PfamiPF08391. Ly49. 1 hit.
[Graphical view]
SUPFAMiSSF56436. SSF56436. 1 hit.

Sequencei

Sequence statusi: Complete.

O75889-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNDQGEIYST LRFLQSPSES QNRLRPDDTQ RPGKTDDKEF SVPWHLIAVT
60 70 80 90 100
LGILCLLLLM IVTVLVTNIF QCIQEKHQRQ EILRNCSEKY IMQNDNYLKE
110 120 130 140 150
QILTNKTLKY DVLKNSFQQK KELDSRLIQK NRCHRENEIV FKVLQNTGKF
160 170 180 190 200
SEDHGSCCGV NCYYFTMQKK DWKGCKQTCQ HCRSSLLKID DKDELVFYIH
210
FYSLGLCFSM LDLRY
Length:215
Mass (Da):25,457
Last modified:November 1, 1998 - v1
Checksum:i2B0A7CCA5A462C80
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF047445 mRNA. Translation: AAC35898.1.
BC069672 mRNA. Translation: AAH69672.1.
BC069734 mRNA. Translation: AAH69734.1.
BC101471 mRNA. Translation: AAI01472.1.
BC101473 mRNA. Translation: AAI01474.1.
CH471094 Genomic DNA. Translation: EAW96193.1.
CH471094 Genomic DNA. Translation: EAW96195.1.
UniGeneiHs.159297.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF047445 mRNA. Translation: AAC35898.1 .
BC069672 mRNA. Translation: AAH69672.1 .
BC069734 mRNA. Translation: AAH69734.1 .
BC101471 mRNA. Translation: AAI01472.1 .
BC101473 mRNA. Translation: AAI01474.1 .
CH471094 Genomic DNA. Translation: EAW96193.1 .
CH471094 Genomic DNA. Translation: EAW96195.1 .
UniGenei Hs.159297.

3D structure databases

ProteinModelPortali O75889.
SMRi O75889. Positions 157-197.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

IntActi O75889. 1 interaction.
STRINGi 9606.ENSP00000023165.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

H-InvDB HIX0036687.

Phylogenomic databases

HOVERGENi HBG053176.

Family and domain databases

Gene3Di 3.10.100.10. 1 hit.
InterProi IPR016186. C-type_lectin-like.
IPR016187. C-type_lectin_fold.
IPR013600. Ly49.
[Graphical view ]
Pfami PF08391. Ly49. 1 hit.
[Graphical view ]
SUPFAMi SSF56436. SSF56436. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Identification of a human member of the Ly-49 multigene family."
    Westgaard I.H., Berg S.F., Orstavik S., Fossum S., Dissen E.
    Eur. J. Immunol. 28:1839-1846(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
  2. "The sequence of the human genome."
    Venter J.C., Adams M.D., Myers E.W., Li P.W., Mural R.J., Sutton G.G., Smith H.O., Yandell M., Evans C.A., Holt R.A., Gocayne J.D., Amanatides P., Ballew R.M., Huson D.H., Wortman J.R., Zhang Q., Kodira C.D., Zheng X.H.
    , Chen L., Skupski M., Subramanian G., Thomas P.D., Zhang J., Gabor Miklos G.L., Nelson C., Broder S., Clark A.G., Nadeau J., McKusick V.A., Zinder N., Levine A.J., Roberts R.J., Simon M., Slayman C., Hunkapiller M., Bolanos R., Delcher A., Dew I., Fasulo D., Flanigan M., Florea L., Halpern A., Hannenhalli S., Kravitz S., Levy S., Mobarry C., Reinert K., Remington K., Abu-Threideh J., Beasley E., Biddick K., Bonazzi V., Brandon R., Cargill M., Chandramouliswaran I., Charlab R., Chaturvedi K., Deng Z., Di Francesco V., Dunn P., Eilbeck K., Evangelista C., Gabrielian A.E., Gan W., Ge W., Gong F., Gu Z., Guan P., Heiman T.J., Higgins M.E., Ji R.R., Ke Z., Ketchum K.A., Lai Z., Lei Y., Li Z., Li J., Liang Y., Lin X., Lu F., Merkulov G.V., Milshina N., Moore H.M., Naik A.K., Narayan V.A., Neelam B., Nusskern D., Rusch D.B., Salzberg S., Shao W., Shue B., Sun J., Wang Z., Wang A., Wang X., Wang J., Wei M., Wides R., Xiao C., Yan C., Yao A., Ye J., Zhan M., Zhang W., Zhang H., Zhao Q., Zheng L., Zhong F., Zhong W., Zhu S., Zhao S., Gilbert D., Baumhueter S., Spier G., Carter C., Cravchik A., Woodage T., Ali F., An H., Awe A., Baldwin D., Baden H., Barnstead M., Barrow I., Beeson K., Busam D., Carver A., Center A., Cheng M.L., Curry L., Danaher S., Davenport L., Desilets R., Dietz S., Dodson K., Doup L., Ferriera S., Garg N., Gluecksmann A., Hart B., Haynes J., Haynes C., Heiner C., Hladun S., Hostin D., Houck J., Howland T., Ibegwam C., Johnson J., Kalush F., Kline L., Koduru S., Love A., Mann F., May D., McCawley S., McIntosh T., McMullen I., Moy M., Moy L., Murphy B., Nelson K., Pfannkoch C., Pratts E., Puri V., Qureshi H., Reardon M., Rodriguez R., Rogers Y.H., Romblad D., Ruhfel B., Scott R., Sitter C., Smallwood M., Stewart E., Strong R., Suh E., Thomas R., Tint N.N., Tse S., Vech C., Wang G., Wetter J., Williams S., Williams M., Windsor S., Winn-Deen E., Wolfe K., Zaveri J., Zaveri K., Abril J.F., Guigo R., Campbell M.J., Sjolander K.V., Karlak B., Kejariwal A., Mi H., Lazareva B., Hatton T., Narechania A., Diemer K., Muruganujan A., Guo N., Sato S., Bafna V., Istrail S., Lippert R., Schwartz R., Walenz B., Yooseph S., Allen D., Basu A., Baxendale J., Blick L., Caminha M., Carnes-Stine J., Caulk P., Chiang Y.H., Coyne M., Dahlke C., Mays A., Dombroski M., Donnelly M., Ely D., Esparham S., Fosler C., Gire H., Glanowski S., Glasser K., Glodek A., Gorokhov M., Graham K., Gropman B., Harris M., Heil J., Henderson S., Hoover J., Jennings D., Jordan C., Jordan J., Kasha J., Kagan L., Kraft C., Levitsky A., Lewis M., Liu X., Lopez J., Ma D., Majoros W., McDaniel J., Murphy S., Newman M., Nguyen T., Nguyen N., Nodell M., Pan S., Peck J., Peterson M., Rowe W., Sanders R., Scott J., Simpson M., Smith T., Sprague A., Stockwell T., Turner R., Venter E., Wang M., Wen M., Wu D., Wu M., Xia A., Zandieh A., Zhu X.
    Science 291:1304-1351(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: BrainImported.
  4. Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiO75889_HUMAN
AccessioniPrimary (citable) accession number: O75889
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1998
Last sequence update: November 1, 1998
Last modified: October 29, 2014
This is version 83 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.