O75889 (O75889_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Killer cell lectin-like receptor subfamily A, member 1 EMBL AAH69672.1

Submitted name:
Killer cell lectin-like receptor subfamily A, member 1, isoform CRA_a EMBL EAW96193.1
Submitted name:
Ly-49L EMBL AAC35898.1

Gene names

Name:	KLRA1 EMBL AAH69672.1 HGNC 6372
Synonyms:	LY49L EMBL AAC35898.1
ORF Names:	hCG_27420 EMBL EAW96193.1

Organism

Homo sapiens (Human) EMBL AAC35898.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	215 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Ligand	Lectin EMBL AAH69672.1
Molecular function	Receptor EMBL AAH69672.1
Gene Ontology (GO)
Biological_process	cell surface receptor signaling pathway Traceable author statement Ref.1. Source: ProtInc
Cellular_component	plasma membrane Traceable author statement Ref.1. Source: ProtInc
Molecular_function	carbohydrate binding Traceable author statement Ref.1. Source: ProtInc transmembrane signaling receptor activity Traceable author statement Ref.1. Source: ProtInc
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	O75889 [UniParc]. Last modified November 1, 1998. Version 1. Checksum: 2B0A7CCA5A462C80	FASTA	215	25,457
	10 20 30 40 50 60 MNDQGEIYST LRFLQSPSES QNRLRPDDTQ RPGKTDDKEF SVPWHLIAVT LGILCLLLLM 70 80 90 100 110 120 IVTVLVTNIF QCIQEKHQRQ EILRNCSEKY IMQNDNYLKE QILTNKTLKY DVLKNSFQQK 130 140 150 160 170 180 KELDSRLIQK NRCHRENEIV FKVLQNTGKF SEDHGSCCGV NCYYFTMQKK DWKGCKQTCQ 190 200 210 HCRSSLLKID DKDELVFYIH FYSLGLCFSM LDLRY

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Identification of a human member of the Ly-49 multigene family." Westgaard I.H., Berg S.F., Orstavik S., Fossum S., Dissen E. Eur. J. Immunol. 28:1839-1846(1998) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[2]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M. , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J. Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Brain EMBL AAI01472.1 and PCR rescued clones EMBL AAH69672.1.
[3]	Mural R.J., Istrail S., Sutton G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C. Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF047445 mRNA. Translation: AAC35898.1. BC069672 mRNA. Translation: AAH69672.1. BC069734 mRNA. Translation: AAH69734.1. BC101471 mRNA. Translation: AAI01472.1. BC101473 mRNA. Translation: AAI01474.1. CH471094 Genomic DNA. Translation: EAW96193.1.
IPI	IPI00009061.
UniGene	Hs.159297.
3D structure databases
HSSP	HSSP built from PDB template 1JA3 based on UniProtKB Q9JHN9.
ProteinModelPortal	O75889.
SMR	O75889. Positions 157-197.
ModBase	Search...
Protein-protein interaction databases
IntAct	O75889. 1 interaction.
STRING	9606.ENSP00000023165. O75889.
Proteomic databases
PRIDE	O75889.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Organism-specific databases
H-InvDB	HIX0036687.
Phylogenomic databases
HOVERGEN	HBG053176.
Gene expression databases
ArrayExpress	O75889.
Family and domain databases
Gene3D	3.10.100.10. 1 hit.
InterPro	IPR016186. C-type_lectin-like. IPR016187. C-type_lectin_fold. IPR013600. Ly49. [Graphical view]
Pfam	PF08391. Ly49. 1 hit. [Graphical view]
SUPFAM	SSF56436. C-type_lectin_fold. 1 hit.
ProtoNet	Search...

Entry information

Entry name

O75889_HUMAN

Accession

Primary (citable) accession number: O75889

Entry history

Integrated into UniProtKB/TrEMBL:	November 1, 1998
Last sequence update:	November 1, 1998
Last modified:	April 3, 2013
This is version 72 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.