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O75889

- O75889_HUMAN

UniProt

O75889 - O75889_HUMAN

Protein
Submitted name:

Killer cell lectin-like receptor subfamily A, member 1

Gene

LY49L

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 82 (01 Oct 2014)
      Sequence version 1 (01 Nov 1998)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. carbohydrate binding Source: ProtInc
    2. transmembrane signaling receptor activity Source: ProtInc

    GO - Biological processi

    1. cell surface receptor signaling pathway Source: ProtInc

    Keywords - Molecular functioni

    ReceptorImported

    Keywords - Ligandi

    LectinImported

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Killer cell lectin-like receptor subfamily A, member 1Imported
    Submitted name:
    Killer cell lectin-like receptor subfamily A, member 1, isoform CRA_aImported
    Submitted name:
    Ly-49LImported
    Gene namesi
    Name:LY49LImported
    Synonyms:KLRA1Imported
    ORF Names:hCG_27420Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    Subcellular locationi

    GO - Cellular componenti

    1. plasma membrane Source: ProtInc

    Interactioni

    Protein-protein interaction databases

    STRINGi9606.ENSP00000023165.

    Structurei

    3D structure databases

    SMRiO75889. Positions 157-197.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    HOVERGENiHBG053176.

    Family and domain databases

    Gene3Di3.10.100.10. 1 hit.
    InterProiIPR016186. C-type_lectin-like.
    IPR016187. C-type_lectin_fold.
    IPR013600. Ly49.
    [Graphical view]
    PfamiPF08391. Ly49. 1 hit.
    [Graphical view]
    SUPFAMiSSF56436. SSF56436. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    O75889-1 [UniParc]FASTAAdd to Basket

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    MNDQGEIYST LRFLQSPSES QNRLRPDDTQ RPGKTDDKEF SVPWHLIAVT    50
    LGILCLLLLM IVTVLVTNIF QCIQEKHQRQ EILRNCSEKY IMQNDNYLKE 100
    QILTNKTLKY DVLKNSFQQK KELDSRLIQK NRCHRENEIV FKVLQNTGKF 150
    SEDHGSCCGV NCYYFTMQKK DWKGCKQTCQ HCRSSLLKID DKDELVFYIH 200
    FYSLGLCFSM LDLRY 215
    Length:215
    Mass (Da):25,457
    Last modified:November 1, 1998 - v1
    Checksum:i2B0A7CCA5A462C80
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF047445 mRNA. Translation: AAC35898.1.
    BC069672 mRNA. Translation: AAH69672.1.
    BC069734 mRNA. Translation: AAH69734.1.
    BC101471 mRNA. Translation: AAI01472.1.
    BC101473 mRNA. Translation: AAI01474.1.
    CH471094 Genomic DNA. Translation: EAW96193.1.
    CH471094 Genomic DNA. Translation: EAW96195.1.
    UniGeneiHs.159297.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF047445 mRNA. Translation: AAC35898.1 .
    BC069672 mRNA. Translation: AAH69672.1 .
    BC069734 mRNA. Translation: AAH69734.1 .
    BC101471 mRNA. Translation: AAI01472.1 .
    BC101473 mRNA. Translation: AAI01474.1 .
    CH471094 Genomic DNA. Translation: EAW96193.1 .
    CH471094 Genomic DNA. Translation: EAW96195.1 .
    UniGenei Hs.159297.

    3D structure databases

    SMRi O75889. Positions 157-197.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 9606.ENSP00000023165.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Organism-specific databases

    H-InvDB HIX0036687.

    Phylogenomic databases

    HOVERGENi HBG053176.

    Family and domain databases

    Gene3Di 3.10.100.10. 1 hit.
    InterProi IPR016186. C-type_lectin-like.
    IPR016187. C-type_lectin_fold.
    IPR013600. Ly49.
    [Graphical view ]
    Pfami PF08391. Ly49. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56436. SSF56436. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Identification of a human member of the Ly-49 multigene family."
      Westgaard I.H., Berg S.F., Orstavik S., Fossum S., Dissen E.
      Eur. J. Immunol. 28:1839-1846(1998) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
    2. "The sequence of the human genome."
      Venter J.C., Adams M.D., Myers E.W., Li P.W., Mural R.J., Sutton G.G., Smith H.O., Yandell M., Evans C.A., Holt R.A., Gocayne J.D., Amanatides P., Ballew R.M., Huson D.H., Wortman J.R., Zhang Q., Kodira C.D., Zheng X.H.
      , Chen L., Skupski M., Subramanian G., Thomas P.D., Zhang J., Gabor Miklos G.L., Nelson C., Broder S., Clark A.G., Nadeau J., McKusick V.A., Zinder N., Levine A.J., Roberts R.J., Simon M., Slayman C., Hunkapiller M., Bolanos R., Delcher A., Dew I., Fasulo D., Flanigan M., Florea L., Halpern A., Hannenhalli S., Kravitz S., Levy S., Mobarry C., Reinert K., Remington K., Abu-Threideh J., Beasley E., Biddick K., Bonazzi V., Brandon R., Cargill M., Chandramouliswaran I., Charlab R., Chaturvedi K., Deng Z., Di Francesco V., Dunn P., Eilbeck K., Evangelista C., Gabrielian A.E., Gan W., Ge W., Gong F., Gu Z., Guan P., Heiman T.J., Higgins M.E., Ji R.R., Ke Z., Ketchum K.A., Lai Z., Lei Y., Li Z., Li J., Liang Y., Lin X., Lu F., Merkulov G.V., Milshina N., Moore H.M., Naik A.K., Narayan V.A., Neelam B., Nusskern D., Rusch D.B., Salzberg S., Shao W., Shue B., Sun J., Wang Z., Wang A., Wang X., Wang J., Wei M., Wides R., Xiao C., Yan C., Yao A., Ye J., Zhan M., Zhang W., Zhang H., Zhao Q., Zheng L., Zhong F., Zhong W., Zhu S., Zhao S., Gilbert D., Baumhueter S., Spier G., Carter C., Cravchik A., Woodage T., Ali F., An H., Awe A., Baldwin D., Baden H., Barnstead M., Barrow I., Beeson K., Busam D., Carver A., Center A., Cheng M.L., Curry L., Danaher S., Davenport L., Desilets R., Dietz S., Dodson K., Doup L., Ferriera S., Garg N., Gluecksmann A., Hart B., Haynes J., Haynes C., Heiner C., Hladun S., Hostin D., Houck J., Howland T., Ibegwam C., Johnson J., Kalush F., Kline L., Koduru S., Love A., Mann F., May D., McCawley S., McIntosh T., McMullen I., Moy M., Moy L., Murphy B., Nelson K., Pfannkoch C., Pratts E., Puri V., Qureshi H., Reardon M., Rodriguez R., Rogers Y.H., Romblad D., Ruhfel B., Scott R., Sitter C., Smallwood M., Stewart E., Strong R., Suh E., Thomas R., Tint N.N., Tse S., Vech C., Wang G., Wetter J., Williams S., Williams M., Windsor S., Winn-Deen E., Wolfe K., Zaveri J., Zaveri K., Abril J.F., Guigo R., Campbell M.J., Sjolander K.V., Karlak B., Kejariwal A., Mi H., Lazareva B., Hatton T., Narechania A., Diemer K., Muruganujan A., Guo N., Sato S., Bafna V., Istrail S., Lippert R., Schwartz R., Walenz B., Yooseph S., Allen D., Basu A., Baxendale J., Blick L., Caminha M., Carnes-Stine J., Caulk P., Chiang Y.H., Coyne M., Dahlke C., Mays A., Dombroski M., Donnelly M., Ely D., Esparham S., Fosler C., Gire H., Glanowski S., Glasser K., Glodek A., Gorokhov M., Graham K., Gropman B., Harris M., Heil J., Henderson S., Hoover J., Jennings D., Jordan C., Jordan J., Kasha J., Kagan L., Kraft C., Levitsky A., Lewis M., Liu X., Lopez J., Ma D., Majoros W., McDaniel J., Murphy S., Newman M., Nguyen T., Nguyen N., Nodell M., Pan S., Peck J., Peterson M., Rowe W., Sanders R., Scott J., Simpson M., Smith T., Sprague A., Stockwell T., Turner R., Venter E., Wang M., Wen M., Wu D., Wu M., Xia A., Zandieh A., Zhu X.
      Science 291:1304-1351(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
    3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
      , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: BrainImported.
    4. Cited for: NUCLEOTIDE SEQUENCE.

    Entry informationi

    Entry nameiO75889_HUMAN
    AccessioniPrimary (citable) accession number: O75889
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 1, 1998
    Last sequence update: November 1, 1998
    Last modified: October 1, 2014
    This is version 82 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.