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Protein
Submitted name:

Killer cell lectin-like receptor subfamily A, member 1

Gene

LY49L

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  • carbohydrate binding Source: ProtInc
  • transmembrane signaling receptor activity Source: ProtInc

GO - Biological processi

  • cell surface receptor signaling pathway Source: ProtInc
Complete GO annotation...

Keywords - Molecular functioni

ReceptorImported

Keywords - Ligandi

LectinImported

Names & Taxonomyi

Protein namesi
Submitted name:
Killer cell lectin-like receptor subfamily A, member 1Imported
Submitted name:
Killer cell lectin-like receptor subfamily A, member 1, isoform CRA_aImported
Submitted name:
Ly-49LImported
Gene namesi
Name:LY49LImported
Synonyms:KLRA1Imported
ORF Names:hCG_27420Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei44 – 70HelicalSequence analysisAdd BLAST27

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: ProtInc
Complete GO annotation...

Keywords - Cellular componenti

Membrane

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini41 – 165Ly49InterPro annotationAdd BLAST125

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

HOVERGENiHBG053176.

Family and domain databases

Gene3Di3.10.100.10. 1 hit.
InterProiIPR016186. C-type_lectin-like/link.
IPR016187. CTDL_fold.
IPR013600. Ly49_N.
[Graphical view]
PfamiPF08391. Ly49. 1 hit.
[Graphical view]
SUPFAMiSSF56436. SSF56436. 1 hit.

Sequencei

Sequence statusi: Complete.

O75889-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNDQGEIYST LRFLQSPSES QNRLRPDDTQ RPGKTDDKEF SVPWHLIAVT
60 70 80 90 100
LGILCLLLLM IVTVLVTNIF QCIQEKHQRQ EILRNCSEKY IMQNDNYLKE
110 120 130 140 150
QILTNKTLKY DVLKNSFQQK KELDSRLIQK NRCHRENEIV FKVLQNTGKF
160 170 180 190 200
SEDHGSCCGV NCYYFTMQKK DWKGCKQTCQ HCRSSLLKID DKDELVFYIH
210
FYSLGLCFSM LDLRY
Length:215
Mass (Da):25,457
Last modified:November 1, 1998 - v1
Checksum:i2B0A7CCA5A462C80
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF047445 mRNA. Translation: AAC35898.1.
BC069672 mRNA. Translation: AAH69672.1.
BC069734 mRNA. Translation: AAH69734.1.
BC101471 mRNA. Translation: AAI01472.1.
BC101473 mRNA. Translation: AAI01474.1.
CH471094 Genomic DNA. Translation: EAW96193.1.
CH471094 Genomic DNA. Translation: EAW96195.1.
UniGeneiHs.159297.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF047445 mRNA. Translation: AAC35898.1.
BC069672 mRNA. Translation: AAH69672.1.
BC069734 mRNA. Translation: AAH69734.1.
BC101471 mRNA. Translation: AAI01472.1.
BC101473 mRNA. Translation: AAI01474.1.
CH471094 Genomic DNA. Translation: EAW96193.1.
CH471094 Genomic DNA. Translation: EAW96195.1.
UniGeneiHs.159297.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

H-InvDBHIX0036687.

Phylogenomic databases

HOVERGENiHBG053176.

Family and domain databases

Gene3Di3.10.100.10. 1 hit.
InterProiIPR016186. C-type_lectin-like/link.
IPR016187. CTDL_fold.
IPR013600. Ly49_N.
[Graphical view]
PfamiPF08391. Ly49. 1 hit.
[Graphical view]
SUPFAMiSSF56436. SSF56436. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiO75889_HUMAN
AccessioniPrimary (citable) accession number: O75889
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1998
Last sequence update: November 1, 1998
Last modified: November 30, 2016
This is version 98 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.