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O75888

- TNF13_HUMAN

UniProt

O75888 - TNF13_HUMAN

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Protein

Tumor necrosis factor ligand superfamily member 13

Gene

TNFSF13

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli

Functioni

Cytokine that binds to TNFRSF13B/TACI and to TNFRSF17/BCMA. Plays a role in the regulation of tumor cell growth. May be involved in monocyte/macrophage-mediated immunological processes.1 Publication

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sitei104 – 1052Cleavage; by furin

GO - Molecular functioni

  1. receptor binding Source: ProtInc

GO - Biological processi

  1. gene expression Source: Reactome
  2. immunoglobulin production in mucosal tissue Source: Ensembl
  3. mRNA metabolic process Source: Reactome
  4. positive regulation of cell proliferation Source: ProtInc
  5. positive regulation of germinal center formation Source: Ensembl
  6. positive regulation of isotype switching to IgA isotypes Source: MGI
  7. RNA metabolic process Source: Reactome
  8. signal transduction Source: ProtInc
Complete GO annotation...

Keywords - Molecular functioni

Cytokine

Keywords - Biological processi

Immunity

Enzyme and pathway databases

ReactomeiREACT_25218. HuR stabilizes mRNA.

Names & Taxonomyi

Protein namesi
Recommended name:
Tumor necrosis factor ligand superfamily member 13
Alternative name(s):
A proliferation-inducing ligand
Short name:
APRIL
TNF- and APOL-related leukocyte expressed ligand 2
Short name:
TALL-2
TNF-related death ligand 1
Short name:
TRDL-1
CD_antigen: CD256
Gene namesi
Name:TNFSF13
Synonyms:APRIL, TALL2, ZTNF2
ORF Names:UNQ383/PRO715
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 17

Organism-specific databases

HGNCiHGNC:11928. TNFSF13.

Subcellular locationi

Secreted 1 Publication

GO - Cellular componenti

  1. cytoplasm Source: UniProt
  2. cytosol Source: Reactome
  3. external side of plasma membrane Source: Ensembl
  4. extracellular space Source: UniProtKB-KW
  5. extracellular vesicular exosome Source: UniProt
  6. nucleoplasm Source: Reactome
Complete GO annotation...

Keywords - Cellular componenti

Secreted

Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Mutagenesisi101 – 1044RKRR → AKRA: Abolishes proteolytic processing. 1 Publication

Organism-specific databases

PharmGKBiPA36621.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Propeptidei1 – 104104PRO_0000034524Add
BLAST
Chaini105 – 250146Tumor necrosis factor ligand superfamily member 13PRO_0000034525Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi124 – 1241N-linked (GlcNAc...)Sequence Analysis
Disulfide bondi196 ↔ 211Sequence Analysis

Post-translational modificationi

The precursor is cleaved by furin.1 Publication

Keywords - PTMi

Cleavage on pair of basic residues, Disulfide bond, Glycoprotein

Proteomic databases

MaxQBiO75888.
PaxDbiO75888.
PRIDEiO75888.

PTM databases

PhosphoSiteiO75888.

Expressioni

Tissue specificityi

Expressed at high levels in transformed cell lines, cancers of colon, thyroid, lymphoid tissues and specifically expressed in monocytes and macrophages.

Inductioni

Down-regulated by phorbol myristate acetate/ionomycin treatment.

Gene expression databases

BgeeiO75888.
CleanExiHS_TNFSF13.
ExpressionAtlasiO75888. baseline.
GenevestigatoriO75888.

Organism-specific databases

HPAiHPA004863.

Interactioni

Subunit structurei

Homotrimer.Curated

Protein-protein interaction databases

BioGridi114278. 10 interactions.
IntActiO75888. 2 interactions.
STRINGi9606.ENSP00000343505.

Structurei

3D structure databases

ProteinModelPortaliO75888.
SMRiO75888. Positions 114-250.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the tumor necrosis factor family.Curated

Phylogenomic databases

eggNOGiNOG45253.
GeneTreeiENSGT00530000063837.
HOGENOMiHOG000036810.
HOVERGENiHBG104367.
InParanoidiO75888.
KOiK05475.
OMAiKGPPGNM.
OrthoDBiEOG7T4MM3.
PhylomeDBiO75888.
TreeFamiTF332331.

Family and domain databases

Gene3Di2.60.120.40. 1 hit.
InterProiIPR021184. TNF_CS.
IPR006052. TNF_dom.
IPR008983. Tumour_necrosis_fac-like_dom.
[Graphical view]
PfamiPF00229. TNF. 1 hit.
[Graphical view]
SMARTiSM00207. TNF. 1 hit.
[Graphical view]
SUPFAMiSSF49842. SSF49842. 1 hit.
PROSITEiPS00251. TNF_1. 1 hit.
PS50049. TNF_2. 1 hit.
[Graphical view]

Sequences (6)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 6 isoformsi produced by alternative splicing. Align

Isoform Alpha (identifier: O75888-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MPASSPFLLA PKGPPGNMGG PVREPALSVA LWLSWGAALG AVACAMALLT
60 70 80 90 100
QQTELQSLRR EVSRLQGTGG PSQNGEGYPW QSLPEQSSDA LEAWENGERS
110 120 130 140 150
RKRRAVLTQK QKKQHSVLHL VPINATSKDD SDVTEVMWQP ALRRGRGLQA
160 170 180 190 200
QGYGVRIQDA GVYLLYSQVL FQDVTFTMGQ VVSREGQGRQ ETLFRCIRSM
210 220 230 240 250
PSHPDRAYNS CYSAGVFHLH QGDILSVIIP RARAKLNLSP HGTFLGFVKL
Length:250
Mass (Da):27,433
Last modified:November 1, 1998 - v1
Checksum:iAE1A6B9457F6E298
GO
Isoform Beta (identifier: O75888-2) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     113-129: KQHSVLHLVPINATSKD → N

Show »
Length:234
Mass (Da):25,678
Checksum:i9F0012E23EBC0780
GO
Isoform Gamma (identifier: O75888-3) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     247-249: Missing.

Show »
Length:247
Mass (Da):27,059
Checksum:iBAB7F6E2989D9DC8
GO
Isoform 4 (identifier: O75888-4) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     86-113: Missing.

Note: No experimental confirmation available.

Show »
Length:222
Mass (Da):24,151
Checksum:iBF3EA9A2F5AB4106
GO
Isoform TWE-PRIL (identifier: O43508-2) [UniParc]FASTAAdd to Basket

The sequence of this isoform can be found in the external entry O43508.
Isoforms of the same protein are often annotated in two different entries if their sequences differ significantly.
Length:330
Mass (Da):36,589
GO
Isoform 5 (identifier: O75888-5) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-17: Missing.
     87-114: Missing.

Note: Gene prediction based on EST data.

Show »
Length:205
Mass (Da):22,488
Checksum:i98217A3D1F58D3FA
GO

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti67 – 671G → R.1 Publication
Corresponds to variant rs11552708 [ dbSNP | Ensembl ].
VAR_052586
Natural varianti96 – 961N → S.1 Publication
Corresponds to variant rs3803800 [ dbSNP | Ensembl ].
VAR_052587

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei1 – 1717Missing in isoform 5. CuratedVSP_046725Add
BLAST
Alternative sequencei86 – 11328Missing in isoform 4. 1 PublicationVSP_043154Add
BLAST
Alternative sequencei87 – 11428Missing in isoform 5. CuratedVSP_046726Add
BLAST
Alternative sequencei113 – 12917KQHSV…ATSKD → N in isoform Beta. 1 PublicationVSP_006450Add
BLAST
Alternative sequencei247 – 2493Missing in isoform Gamma. 2 PublicationsVSP_006451

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF046888 mRNA. Translation: AAC61312.1.
AF136294 mRNA. Translation: AAD29422.1.
AF184972 mRNA. Translation: AAF01321.1.
AF114011 mRNA. Translation: AAF59828.1.
AF114012 mRNA. Translation: AAF59829.1.
AF114013 mRNA. Translation: AAF59830.1.
AY358880 mRNA. Translation: AAQ89239.1.
AY081050 mRNA. Translation: AAL90442.1.
AB222992 Genomic DNA. Translation: BAE16556.1.
AK301221 mRNA. Translation: BAG62794.1.
BT019561 mRNA. Translation: AAV38368.1.
BT019562 mRNA. Translation: AAV38369.1.
AC016876 Genomic DNA. No translation available.
BC008042 mRNA. Translation: AAH08042.1.
CCDSiCCDS11111.1. [O75888-1]
CCDS11112.1. [O75888-2]
CCDS42256.1. [O75888-3]
CCDS56019.1. [O75888-5]
RefSeqiNP_001185552.1. NM_001198623.1. [O75888-4]
NP_001185553.1. NM_001198624.1. [O75888-5]
NP_003799.1. NM_003808.3. [O75888-1]
NP_742084.1. NM_172087.2. [O75888-2]
NP_742085.1. NM_172088.2. [O75888-3]
UniGeneiHs.54673.

Genome annotation databases

EnsembliENST00000338784; ENSP00000343505; ENSG00000161955. [O75888-1]
ENST00000349228; ENSP00000314455; ENSG00000161955. [O75888-2]
ENST00000396542; ENSP00000379792; ENSG00000161955. [O75888-5]
ENST00000396545; ENSP00000379794; ENSG00000161955. [O75888-3]
GeneIDi8741.
KEGGihsa:8741.
UCSCiuc002ghj.2. human. [O75888-3]
uc002ghk.2. human. [O75888-1]
uc002ghl.2. human. [O75888-2]
uc010vua.1. human. [O75888-4]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF046888 mRNA. Translation: AAC61312.1 .
AF136294 mRNA. Translation: AAD29422.1 .
AF184972 mRNA. Translation: AAF01321.1 .
AF114011 mRNA. Translation: AAF59828.1 .
AF114012 mRNA. Translation: AAF59829.1 .
AF114013 mRNA. Translation: AAF59830.1 .
AY358880 mRNA. Translation: AAQ89239.1 .
AY081050 mRNA. Translation: AAL90442.1 .
AB222992 Genomic DNA. Translation: BAE16556.1 .
AK301221 mRNA. Translation: BAG62794.1 .
BT019561 mRNA. Translation: AAV38368.1 .
BT019562 mRNA. Translation: AAV38369.1 .
AC016876 Genomic DNA. No translation available.
BC008042 mRNA. Translation: AAH08042.1 .
CCDSi CCDS11111.1. [O75888-1 ]
CCDS11112.1. [O75888-2 ]
CCDS42256.1. [O75888-3 ]
CCDS56019.1. [O75888-5 ]
RefSeqi NP_001185552.1. NM_001198623.1. [O75888-4 ]
NP_001185553.1. NM_001198624.1. [O75888-5 ]
NP_003799.1. NM_003808.3. [O75888-1 ]
NP_742084.1. NM_172087.2. [O75888-2 ]
NP_742085.1. NM_172088.2. [O75888-3 ]
UniGenei Hs.54673.

3D structure databases

ProteinModelPortali O75888.
SMRi O75888. Positions 114-250.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 114278. 10 interactions.
IntActi O75888. 2 interactions.
STRINGi 9606.ENSP00000343505.

PTM databases

PhosphoSitei O75888.

Proteomic databases

MaxQBi O75888.
PaxDbi O75888.
PRIDEi O75888.

Protocols and materials databases

DNASUi 8741.
Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000338784 ; ENSP00000343505 ; ENSG00000161955 . [O75888-1 ]
ENST00000349228 ; ENSP00000314455 ; ENSG00000161955 . [O75888-2 ]
ENST00000396542 ; ENSP00000379792 ; ENSG00000161955 . [O75888-5 ]
ENST00000396545 ; ENSP00000379794 ; ENSG00000161955 . [O75888-3 ]
GeneIDi 8741.
KEGGi hsa:8741.
UCSCi uc002ghj.2. human. [O75888-3 ]
uc002ghk.2. human. [O75888-1 ]
uc002ghl.2. human. [O75888-2 ]
uc010vua.1. human. [O75888-4 ]

Organism-specific databases

CTDi 8741.
GeneCardsi GC17P007461.
HGNCi HGNC:11928. TNFSF13.
HPAi HPA004863.
MIMi 604472. gene.
neXtProti NX_O75888.
PharmGKBi PA36621.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG45253.
GeneTreei ENSGT00530000063837.
HOGENOMi HOG000036810.
HOVERGENi HBG104367.
InParanoidi O75888.
KOi K05475.
OMAi KGPPGNM.
OrthoDBi EOG7T4MM3.
PhylomeDBi O75888.
TreeFami TF332331.

Enzyme and pathway databases

Reactomei REACT_25218. HuR stabilizes mRNA.

Miscellaneous databases

GeneWikii TNFSF13.
GenomeRNAii 8741.
NextBioi 32793.
PROi O75888.
SOURCEi Search...

Gene expression databases

Bgeei O75888.
CleanExi HS_TNFSF13.
ExpressionAtlasi O75888. baseline.
Genevestigatori O75888.

Family and domain databases

Gene3Di 2.60.120.40. 1 hit.
InterProi IPR021184. TNF_CS.
IPR006052. TNF_dom.
IPR008983. Tumour_necrosis_fac-like_dom.
[Graphical view ]
Pfami PF00229. TNF. 1 hit.
[Graphical view ]
SMARTi SM00207. TNF. 1 hit.
[Graphical view ]
SUPFAMi SSF49842. SSF49842. 1 hit.
PROSITEi PS00251. TNF_1. 1 hit.
PS50049. TNF_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Tissue: Uterus.
  2. "TALL-1 is a novel member of the TNF family that is down-regulated by mitogens."
    Shu H.-B., Hu W.-H., Johnson H.
    J. Leukoc. Biol. 65:680-683(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
  3. "Homo sapiens tumor necrosis factor homolog."
    Farrah T., Grant F., Haldeman B., Whitmore T., Gross J., O'Hara P.
    Submitted (OCT-1999) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
  4. "APRIL/TRDL-1, a tumor necrosis factor-like ligand, stimulates cell death."
    Kelly K.A., Manos E.J., Jensen G.T., Nadauld L., Jones D.A.
    Cancer Res. 60:1021-1027(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS ALPHA; BETA AND GAMMA).
  5. "An endogenous hybrid mRNA encodes TWE-PRIL, a functional cell surface TWEAK-APRIL fusion protein."
    Pradet-Balade B., Medema J.P., Lopez-Fraga M., Lozano J.C., Kolfschoten G.M., Picard A., Martinez-A C., Garcia-Sanz J.A., Hahne M.
    EMBO J. 21:5711-5720(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM ALPHA).
  6. "Polymorphisms of human APRIL gene."
    Kawasaki A., Tsuchiya N., Kusaoi M., Murakami T., Fukazawa T., Matsuta K., Hashimoto H., Tokunaga K.
    Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  7. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM ALPHA).
  8. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 4).
    Tissue: Spleen.
  9. "Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
    Kalnine N., Chen X., Rolfs A., Halleck A., Hines L., Eisenstein S., Koundinya M., Raphael J., Moreira D., Kelley T., LaBaer J., Lin Y., Phelan M., Farmer A.
    Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM ALPHA), VARIANT ARG-67.
  10. "DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage."
    Zody M.C., Garber M., Adams D.J., Sharpe T., Harrow J., Lupski J.R., Nicholson C., Searle S.M., Wilming L., Young S.K., Abouelleil A., Allen N.R., Bi W., Bloom T., Borowsky M.L., Bugalter B.E., Butler J., Chang J.L.
    , Chen C.-K., Cook A., Corum B., Cuomo C.A., de Jong P.J., DeCaprio D., Dewar K., FitzGerald M., Gilbert J., Gibson R., Gnerre S., Goldstein S., Grafham D.V., Grocock R., Hafez N., Hagopian D.S., Hart E., Norman C.H., Humphray S., Jaffe D.B., Jones M., Kamal M., Khodiyar V.K., LaButti K., Laird G., Lehoczky J., Liu X., Lokyitsang T., Loveland J., Lui A., Macdonald P., Major J.E., Matthews L., Mauceli E., McCarroll S.A., Mihalev A.H., Mudge J., Nguyen C., Nicol R., O'Leary S.B., Osoegawa K., Schwartz D.C., Shaw-Smith C., Stankiewicz P., Steward C., Swarbreck D., Venkataraman V., Whittaker C.A., Yang X., Zimmer A.R., Bradley A., Hubbard T., Birren B.W., Rogers J., Lander E.S., Nusbaum C.
    Nature 440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  11. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM GAMMA), VARIANT SER-96.
    Tissue: Ovary.
  12. Cited for: FUNCTION.
  13. "Biologically active APRIL is secreted following intracellular processing in the Golgi apparatus by furin convertase."
    Lopez-Fraga M., Fernandez R., Albar J.P., Hahne M.
    EMBO Rep. 2:945-951(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: PROTEOLYTIC PROCESSING BY FURIN, MUTAGENESIS OF 101-ARG--ARG-104, SUBCELLULAR LOCATION.

Entry informationi

Entry nameiTNF13_HUMAN
AccessioniPrimary (citable) accession number: O75888
Secondary accession number(s): A8MYD5
, B4DVT2, Q541E1, Q5U0G8, Q96HV6, Q9P1M8, Q9P1M9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 21, 2001
Last sequence update: November 1, 1998
Last modified: October 29, 2014
This is version 141 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human cell differentiation molecules
    CD nomenclature of surface proteins of human leucocytes and list of entries
  2. Human chromosome 17
    Human chromosome 17: entries, gene names and cross-references to MIM
  3. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  4. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  5. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  6. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3