Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

O75886

- STAM2_HUMAN

UniProt

O75886 - STAM2_HUMAN

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Signal transducing adapter molecule 2

Gene

STAM2

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli

Functioni

Involved in intracellular signal transduction mediated by cytokines and growth factors. Upon IL-2 and GM-CSL stimulation, it plays a role in signaling leading to DNA synthesis and MYC induction. May also play a role in T-cell development. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with HGS (ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes (By similarity).By similarity

GO - Biological processi

  1. endosomal transport Source: Reactome
  2. epidermal growth factor receptor signaling pathway Source: Reactome
  3. intracellular protein transport Source: InterPro
  4. membrane organization Source: Reactome
  5. negative regulation of epidermal growth factor receptor signaling pathway Source: Reactome
Complete GO annotation...

Keywords - Biological processi

Protein transport, Transport

Enzyme and pathway databases

ReactomeiREACT_12484. EGFR downregulation.
REACT_27258. Endosomal Sorting Complex Required For Transport (ESCRT).

Names & Taxonomyi

Protein namesi
Recommended name:
Signal transducing adapter molecule 2
Short name:
STAM-2
Alternative name(s):
Hrs-binding protein
Gene namesi
Name:STAM2
Synonyms:HBP
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 2

Organism-specific databases

HGNCiHGNC:11358. STAM2.

Subcellular locationi

Cytoplasm By similarity. Early endosome membrane 1 Publication; Peripheral membrane protein 1 Publication; Cytoplasmic side 1 Publication

GO - Cellular componenti

  1. cytoplasm Source: LIFEdb
  2. cytosol Source: Reactome
  3. endosome Source: UniProtKB-KW
  4. intracellular membrane-bounded organelle Source: HPA
  5. membrane Source: UniProtKB-KW
  6. nucleus Source: HPA
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Endosome, Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA36180.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 525525Signal transducing adapter molecule 2PRO_0000190147Add
BLAST

Post-translational modificationi

Phosphorylated in response to IL-2, GM-CSF, EGF and PDGF.

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiO75886.
PaxDbiO75886.
PRIDEiO75886.

PTM databases

PhosphoSiteiO75886.

Expressioni

Tissue specificityi

Ubiquitously expressed.1 Publication

Gene expression databases

BgeeiO75886.
CleanExiHS_STAM2.
GenevestigatoriO75886.

Organism-specific databases

HPAiHPA035528.
HPA035529.

Interactioni

Subunit structurei

Component of the ESCRT-0 complex composed of STAM or STAM2 and HGS. Part of a complex at least composed of HSG, STAM2 and EPS15. Interacts with JAK2 and JAK3. Interacts with ubiquitinated proteins and the deubiquitinating enzyme USP8/UBPY (By similarity). Interacts (via the via the PxVxL motif) with CBX5; the interaction is direct. Interacts with VPS37C. Interacts with ubiquitin; the interaction is direct.By similarity4 Publications

Binary interactionsi

WithEntry#Exp.IntActNotes
LCP2Q130943EBI-373258,EBI-346946
RIN1Q136714EBI-373258,EBI-366017
STAMBPO956303EBI-373258,EBI-396676

Protein-protein interaction databases

BioGridi115548. 41 interactions.
IntActiO75886. 17 interactions.
MINTiMINT-145850.
STRINGi9606.ENSP00000263904.

Structurei

Secondary structure

1
525
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi10 – 167
Helixi26 – 3813
Beta strandi39 – 413
Helixi42 – 5413
Helixi59 – 7517
Helixi78 – 847
Helixi87 – 9812
Helixi103 – 11917
Turni120 – 1223
Turni124 – 1263
Helixi127 – 13711
Turni138 – 1403
Beta strandi205 – 2117
Beta strandi217 – 2193
Beta strandi228 – 2336
Beta strandi237 – 2448
Beta strandi247 – 2515
Helixi253 – 2553
Beta strandi256 – 2583

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1X2QNMR-A195-269[»]
1X5BNMR-A1-150[»]
2L0TNMR-B1-150[»]
ProteinModelPortaliO75886.
SMRiO75886. Positions 1-150, 196-367.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiO75886.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini16 – 144129VHSPROSITE-ProRule annotationAdd
BLAST
Repeati165 – 18420UIMAdd
BLAST
Domaini202 – 26160SH3PROSITE-ProRule annotationAdd
BLAST
Domaini360 – 37718ITAMAdd
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni219 – 2202Interaction with USP8By similarity
Regioni334 – 36835Interaction with HGSBy similarityAdd
BLAST

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi54 – 6714PxVxL motifAdd
BLAST

Domaini

The VHS and UIM domains mediate the interaction with ubiquitinated proteins.
The SH3 domain mediates the interaction with USP8.
Contains one Pro-Xaa-Val-Xaa-Leu (PxVxL) motif, which is required for interaction with chromoshadow domains. This motif requires additional residues -7, -6, +4 and +5 of the central Val which contact the chromoshadow domain.

Sequence similaritiesi

Belongs to the STAM family.Curated
Contains 1 ITAM domain.Curated
Contains 1 SH3 domain.PROSITE-ProRule annotation
Contains 1 UIM (ubiquitin-interacting motif) repeat.PROSITE-ProRule annotation
Contains 1 VHS domain.PROSITE-ProRule annotation

Keywords - Domaini

SH3 domain

Phylogenomic databases

eggNOGiNOG309509.
GeneTreeiENSGT00700000104139.
HOGENOMiHOG000231952.
HOVERGENiHBG053175.
InParanoidiO75886.
KOiK04705.
OMAiHYPPASS.
OrthoDBiEOG7353WJ.
PhylomeDBiO75886.
TreeFamiTF315007.

Family and domain databases

Gene3Di1.25.40.90. 1 hit.
InterProiIPR008942. ENTH_VHS.
IPR001452. SH3_domain.
IPR003903. Ubiquitin-int_motif.
IPR002014. VHS.
IPR018205. VHS_subgr.
[Graphical view]
PfamiPF00018. SH3_1. 1 hit.
PF02809. UIM. 1 hit.
PF00790. VHS. 1 hit.
[Graphical view]
PRINTSiPR00452. SH3DOMAIN.
SMARTiSM00326. SH3. 1 hit.
SM00726. UIM. 1 hit.
SM00288. VHS. 1 hit.
[Graphical view]
SUPFAMiSSF48464. SSF48464. 1 hit.
SSF50044. SSF50044. 1 hit.
PROSITEiPS50002. SH3. 1 hit.
PS50330. UIM. 1 hit.
PS50179. VHS. 1 hit.
[Graphical view]

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. Align

Isoform 1 (identifier: O75886) [UniParc]FASTAAdd to Basket

Also known as: STAM2A

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MPLFTANPFE QDVEKATNEY NTTEDWSLIM DICDKVGSTP NGAKDCLKAI
60 70 80 90 100
MKRVNHKVPH VALQALTLLG ACVANCGKIF HLEVCSRDFA TEVRAVIKNK
110 120 130 140 150
AHPKVCEKLK SLMVEWSEEF QKDPQFSLIS ATIKSMKEEG ITFPPAGSQT
160 170 180 190 200
VSAAAKNGTS SNKNKEDEDI AKAIELSLQE QKQQHTETKS LYPSSEIQLN
210 220 230 240 250
NKVARKVRAL YDFEAVEDNE LTFKHGEIII VLDDSDANWW KGENHRGIGL
260 270 280 290 300
FPSNFVTTNL NIETEAAAVD KLNVIDDDVE EIKKSEPEPV YIDEDKMDRA
310 320 330 340 350
LQVLQSIDPT DSKPDSQDLL DLEDICQQMG PMIDEKLEEI DRKHSELSEL
360 370 380 390 400
NVKVLEALEL YNKLVNEAPV YSVYSKLHPP AHYPPASSGV PMQTYPVQSH
410 420 430 440 450
GGNYMGQSIH QVTVAQSYSL GPDQIGPLRS LPPNVNSSVT AQPAQTSYLS
460 470 480 490 500
TGQDTVSNPT YMNQNSNLQS ATGTTAYTQQ MGMSVDMSSY QNTTSNLPQL
510 520
AGFPVTVPAH PVAQQHTNYH QQPLL
Length:525
Mass (Da):58,164
Last modified:November 1, 1998 - v1
Checksum:i408D484544DD9403
GO
Isoform 2 (identifier: O75886-2) [UniParc]FASTAAdd to Basket

Also known as: STAM2B

The sequence of this isoform differs from the canonical sequence as follows:
     343-525: Missing.

Show »
Length:342
Mass (Da):38,370
Checksum:iE54540C48B6CD1B3
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti81 – 833HLE → RLG in CAB63735. (PubMed:11230166)Curated
Sequence conflicti254 – 2541N → D in CAB63735. (PubMed:11230166)Curated
Sequence conflicti266 – 2661A → V in CAB63735. (PubMed:11230166)Curated

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei343 – 525183Missing in isoform 2. 1 PublicationVSP_014848Add
BLAST

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF042273 mRNA. Translation: AAC63963.1.
AF042274 mRNA. Translation: AAC63964.1.
AL133600 mRNA. Translation: CAB63735.1.
AK292265 mRNA. Translation: BAF84954.1.
AK292847 mRNA. Translation: BAF85536.1.
AC079790 Genomic DNA. Translation: AAY14712.1.
CH471058 Genomic DNA. Translation: EAX11490.1.
CH471058 Genomic DNA. Translation: EAX11492.1.
BC028740 mRNA. Translation: AAH28740.1.
CCDSiCCDS2196.1. [O75886-1]
PIRiT43437.
RefSeqiNP_005834.4. NM_005843.4. [O75886-1]
UniGeneiHs.17200.

Genome annotation databases

EnsembliENST00000263904; ENSP00000263904; ENSG00000115145. [O75886-1]
GeneIDi10254.
KEGGihsa:10254.
UCSCiuc002tyc.4. human. [O75886-1]

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF042273 mRNA. Translation: AAC63963.1 .
AF042274 mRNA. Translation: AAC63964.1 .
AL133600 mRNA. Translation: CAB63735.1 .
AK292265 mRNA. Translation: BAF84954.1 .
AK292847 mRNA. Translation: BAF85536.1 .
AC079790 Genomic DNA. Translation: AAY14712.1 .
CH471058 Genomic DNA. Translation: EAX11490.1 .
CH471058 Genomic DNA. Translation: EAX11492.1 .
BC028740 mRNA. Translation: AAH28740.1 .
CCDSi CCDS2196.1. [O75886-1 ]
PIRi T43437.
RefSeqi NP_005834.4. NM_005843.4. [O75886-1 ]
UniGenei Hs.17200.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
1X2Q NMR - A 195-269 [» ]
1X5B NMR - A 1-150 [» ]
2L0T NMR - B 1-150 [» ]
ProteinModelPortali O75886.
SMRi O75886. Positions 1-150, 196-367.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 115548. 41 interactions.
IntActi O75886. 17 interactions.
MINTi MINT-145850.
STRINGi 9606.ENSP00000263904.

PTM databases

PhosphoSitei O75886.

Proteomic databases

MaxQBi O75886.
PaxDbi O75886.
PRIDEi O75886.

Protocols and materials databases

DNASUi 10254.
Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000263904 ; ENSP00000263904 ; ENSG00000115145 . [O75886-1 ]
GeneIDi 10254.
KEGGi hsa:10254.
UCSCi uc002tyc.4. human. [O75886-1 ]

Organism-specific databases

CTDi 10254.
GeneCardsi GC02M152939.
HGNCi HGNC:11358. STAM2.
HPAi HPA035528.
HPA035529.
MIMi 606244. gene.
neXtProti NX_O75886.
PharmGKBi PA36180.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG309509.
GeneTreei ENSGT00700000104139.
HOGENOMi HOG000231952.
HOVERGENi HBG053175.
InParanoidi O75886.
KOi K04705.
OMAi HYPPASS.
OrthoDBi EOG7353WJ.
PhylomeDBi O75886.
TreeFami TF315007.

Enzyme and pathway databases

Reactomei REACT_12484. EGFR downregulation.
REACT_27258. Endosomal Sorting Complex Required For Transport (ESCRT).

Miscellaneous databases

EvolutionaryTracei O75886.
GeneWikii STAM2.
GenomeRNAii 10254.
NextBioi 38856.
PROi O75886.
SOURCEi Search...

Gene expression databases

Bgeei O75886.
CleanExi HS_STAM2.
Genevestigatori O75886.

Family and domain databases

Gene3Di 1.25.40.90. 1 hit.
InterProi IPR008942. ENTH_VHS.
IPR001452. SH3_domain.
IPR003903. Ubiquitin-int_motif.
IPR002014. VHS.
IPR018205. VHS_subgr.
[Graphical view ]
Pfami PF00018. SH3_1. 1 hit.
PF02809. UIM. 1 hit.
PF00790. VHS. 1 hit.
[Graphical view ]
PRINTSi PR00452. SH3DOMAIN.
SMARTi SM00326. SH3. 1 hit.
SM00726. UIM. 1 hit.
SM00288. VHS. 1 hit.
[Graphical view ]
SUPFAMi SSF48464. SSF48464. 1 hit.
SSF50044. SSF50044. 1 hit.
PROSITEi PS50002. SH3. 1 hit.
PS50330. UIM. 1 hit.
PS50179. VHS. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2), TISSUE SPECIFICITY, INTERACTION WITH JAK2 AND JAK3.
    Tissue: Fetal brain.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
    Tissue: Brain.
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
    Tissue: Testis and Trachea.
  4. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
    Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H.
    , Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., Wilson R.K.
    Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  5. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
    Tissue: Brain.
  7. "STAM and Hrs are subunits of a multivalent ubiquitin-binding complex on early endosomes."
    Bache K.G., Raiborg C., Mehlum A., Stenmark H.
    J. Biol. Chem. 278:12513-12521(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: INTERACTION WITH HGS AND UBIQUITIN, IDENTIFICATION IN A COMPLEX WITH HSG AND EPS15, SUBCELLULAR LOCATION.
  8. "Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry."
    Brill L.M., Salomon A.R., Ficarro S.B., Mukherji M., Stettler-Gill M., Peters E.C.
    Anal. Chem. 76:2763-2772(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Leukemic T-cell.
  9. "The mammalian heterochromatin protein 1 binds diverse nuclear proteins through a common motif that targets the chromoshadow domain."
    Lechner M.S., Schultz D.C., Negorev D., Maul G.G., Rauscher F.J. III
    Biochem. Biophys. Res. Commun. 331:929-937(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: INTERACTION WITH CBX5.
  10. "Identification of human VPS37C, a component of endosomal sorting complex required for transport-I important for viral budding."
    Eastman S.W., Martin-Serrano J., Chung W., Zang T., Bieniasz P.D.
    J. Biol. Chem. 280:628-636(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: INTERACTION WITH VPS37C.
  11. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  12. "The solution structure of the VHS and SH3 domains of human signal transducing adaptor molecule 2."
    RIKEN structural genomics initiative (RSGI)
    Submitted (NOV-2005) to the PDB data bank
    Cited for: STRUCTURE BY NMR OF 1-269.

Entry informationi

Entry nameiSTAM2_HUMAN
AccessioniPrimary (citable) accession number: O75886
Secondary accession number(s): A8K8A0
, D3DPA1, Q7LDQ0, Q9UF58
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 19, 2005
Last sequence update: November 1, 1998
Last modified: October 29, 2014
This is version 141 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Human chromosome 2
    Human chromosome 2: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  4. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3