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O75717

- WDHD1_HUMAN

UniProt

O75717 - WDHD1_HUMAN

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Protein
WD repeat and HMG-box DNA-binding protein 1
Gene
WDHD1, AND1
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5 - Experimental evidence at protein leveli

Functioni

Acts as a replication initiation factor that brings together the MCM2-7 helicase and the DNA polymerase alpha/primase complex in order to initiate DNA replication.1 Publication

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi1016 – 107964HMG box
Add
BLAST

GO - Molecular functioni

  1. DNA binding Source: ProtInc
  2. RNA binding Source: Ensembl
  3. chromatin binding Source: Ensembl
  4. protein binding Source: IntAct

GO - Biological processi

  1. RNA processing Source: Ensembl
  2. heterochromatin maintenance Source: Ensembl
  3. regulation of chromosome organization Source: Ensembl
Complete GO annotation...

Keywords - Ligandi

DNA-binding

Enzyme and pathway databases

SignaLinkiO75717.

Names & Taxonomyi

Protein namesi
Recommended name:
WD repeat and HMG-box DNA-binding protein 1
Alternative name(s):
Acidic nucleoplasmic DNA-binding protein 1
Short name:
And-1
Gene namesi
Name:WDHD1
Synonyms:AND1
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 14

Organism-specific databases

HGNCiHGNC:23170. WDHD1.

Subcellular locationi

Nucleusnucleoplasm By similarity

GO - Cellular componenti

  1. chromosome, centromeric region Source: Ensembl
  2. cytoplasm Source: ProtInc
  3. nucleoplasm Source: ProtInc
  4. nucleus Source: HPA
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA134988782.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 11291129WD repeat and HMG-box DNA-binding protein 1
PRO_0000051338Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei333 – 3331Phosphoserine3 Publications
Modified residuei374 – 3741Phosphoserine3 Publications
Modified residuei383 – 3831Phosphoserine5 Publications
Modified residuei387 – 3871Phosphoserine2 Publications
Modified residuei671 – 6711N6-acetyllysine By similarity
Modified residuei824 – 8241Phosphothreonine1 Publication
Modified residuei868 – 8681Phosphoserine3 Publications
Modified residuei962 – 9621N6-acetyllysine1 Publication
Modified residuei984 – 9841Phosphoserine1 Publication
Modified residuei1090 – 10901Phosphoserine1 Publication

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

MaxQBiO75717.
PaxDbiO75717.
PRIDEiO75717.

PTM databases

PhosphoSiteiO75717.

Expressioni

Gene expression databases

ArrayExpressiO75717.
BgeeiO75717.
CleanExiHS_WDHD1.
GenevestigatoriO75717.

Organism-specific databases

HPAiHPA001122.

Interactioni

Subunit structurei

Interacts with the polymerase alpha catalytic subunit POLA1. Interacts with MCM10. Interacts with DNA2.2 Publications

Binary interactionsi

WithEntry#Exp.IntActNotes
KAT2AQ928305EBI-3951691,EBI-477622

Protein-protein interaction databases

BioGridi116340. 30 interactions.
IntActiO75717. 2 interactions.
STRINGi9606.ENSP00000353793.

Structurei

Secondary structure

Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi1021 – 103616
Helixi1043 – 105412
Beta strandi1055 – 10573
Helixi1059 – 106810
Beta strandi1071 – 10766
Helixi1081 – 10833

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2D7LNMR-A1017-1084[»]
ProteinModelPortaliO75717.
SMRiO75717. Positions 11-284, 1017-1084.

Miscellaneous databases

EvolutionaryTraceiO75717.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Repeati11 – 5040WD 1
Add
BLAST
Repeati52 – 9140WD 2
Add
BLAST
Repeati92 – 13140WD 3
Add
BLAST
Repeati134 – 17340WD 4
Add
BLAST
Repeati184 – 22340WD 5
Add
BLAST
Repeati228 – 26740WD 6
Add
BLAST
Repeati271 – 31040WD 7
Add
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi829 – 8368Glu-rich (acidic)
Compositional biasi862 – 87817Asp/Glu-rich (acidic)
Add
BLAST

Sequence similaritiesi

Contains 7 WD repeats.

Keywords - Domaini

Repeat, WD repeat

Phylogenomic databases

eggNOGiCOG2319.
HOGENOMiHOG000015160.
HOVERGENiHBG074190.
InParanoidiO75717.
KOiK11274.
OMAiWTPICNT.
OrthoDBiEOG7J70F9.
PhylomeDBiO75717.
TreeFamiTF105988.

Family and domain databases

Gene3Di1.10.30.10. 1 hit.
2.130.10.10. 1 hit.
InterProiIPR022100. DUF3639.
IPR009071. HMG_box_dom.
IPR013979. TIF_beta_prop-like.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR019775. WD40_repeat_CS.
IPR017986. WD40_repeat_dom.
[Graphical view]
PfamiPF12341. DUF3639. 1 hit.
PF08662. eIF2A. 1 hit.
PF00505. HMG_box. 1 hit.
PF00400. WD40. 2 hits.
[Graphical view]
SMARTiSM00398. HMG. 1 hit.
SM00320. WD40. 5 hits.
[Graphical view]
SUPFAMiSSF47095. SSF47095. 1 hit.
SSF50978. SSF50978. 1 hit.
PROSITEiPS50118. HMG_BOX_2. 1 hit.
PS00678. WD_REPEATS_1. 1 hit.
PS50082. WD_REPEATS_2. 3 hits.
PS50294. WD_REPEATS_REGION. 1 hit.
[Graphical view]

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. Align

Isoform 1 (identifier: O75717-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

MPATRKPMRY GHTEGHTEVC FDDSGSFIVT CGSDGDVRIW EDLDDDDPKF     50
INVGEKAYSC ALKSGKLVTA VSNNTIQVHT FPEGVPDGIL TRFTTNANHV 100
VFNGDGTKIA AGSSDFLVKI VDVMDSSQQK TFRGHDAPVL SLSFDPKDIF 150
LASASCDGSV RVWQISDQTC AISWPLLQKC NDVINAKSIC RLAWQPKSGK 200
LLAIPVEKSV KLYRRESWSH QFDLSDNFIS QTLNIVTWSP CGQYLAAGSI 250
NGLIIVWNVE TKDCMERVKH EKGYAICGLA WHPTCGRISY TDAEGNLGLL 300
ENVCDPSGKT SSSKVSSRVE KDYNDLFDGD DMSNAGDFLN DNAVEIPSFS 350
KGIINDDEDD EDLMMASGRP RQRSHILEDD ENSVDISMLK TGSSLLKEEE 400
EDGQEGSIHN LPLVTSQRPF YDGPMPTPRQ KPFQSGSTPL HLTHRFMVWN 450
SIGIIRCYND EQDNAIDVEF HDTSIHHATH LSNTLNYTIA DLSHEAILLA 500
CESTDELASK LHCLHFSSWD SSKEWIIDLP QNEDIEAICL GQGWAAAATS 550
ALLLRLFTIG GVQKEVFSLA GPVVSMAGHG EQLFIVYHRG TGFDGDQCLG 600
VQLLELGKKK KQILHGDPLP LTRKSYLAWI GFSAEGTPCY VDSEGIVRML 650
NRGLGNTWTP ICNTREHCKG KSDHYWVVGI HENPQQLRCI PCKGSRFPPT 700
LPRPAVAILS FKLPYCQIAT EKGQMEEQFW RSVIFHNHLD YLAKNGYEYE 750
ESTKNQATKE QQELLMKMLA LSCKLEREFR CVELADLMTQ NAVNLAIKYA 800
SRSRKLILAQ KLSELAVEKA AELTATQVEE EEEEEDFRKK LNAGYSNTAT 850
EWSQPRFRNQ VEEDAEDSGE ADDEEKPEIH KPGQNSFSKS TNSSDVSAKS 900
GAVTFSSQGR VNPFKVSASS KEPAMSMNSA RSTNILDNMG KSSKKSTALS 950
RTTNNEKSPI IKPLIPKPKP KQASAASYFQ KRNSQTNKTE EVKEENLKNV 1000
LSETPAICPP QNTENQRPKT GFQMWLEENR SNILSDNPDF SDEADIIKEG 1050
MIRFRVLSTE ERKVWANKAK GETASEGTEA KKRKRVVDES DETENQEEKA 1100
KENLNLSKKQ KPLDFSTNQK LSAFAFKQE 1129
Length:1,129
Mass (Da):125,967
Last modified:November 1, 1998 - v1
Checksum:iDD3E3613CA6AE70A
GO
Isoform 2 (identifier: O75717-2) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-123: Missing.

Note: No experimental confirmation available. Derived from EST data.

Show »
Length:1,006
Mass (Da):112,705
Checksum:i430FD72EAB983984
GO

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti338 – 3381F → L.
Corresponds to variant rs8020032 [ dbSNP | Ensembl ].
VAR_053422
Natural varianti411 – 4111L → P.
Corresponds to variant rs17128116 [ dbSNP | Ensembl ].
VAR_053423
Natural varianti1102 – 11021E → K.
Corresponds to variant rs41309252 [ dbSNP | Ensembl ].
VAR_062100

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei1 – 123123Missing in isoform 2.
VSP_054775Add
BLAST

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti612 – 6121Q → K in AAH43349. 1 Publication
Sequence conflicti612 – 6121Q → K in AAH00622. 1 Publication
Sequence conflicti613 – 6131I → K in AAH00622. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ006266 mRNA. Translation: CAA06932.1.
AL160471 Genomic DNA. No translation available.
BC000622 mRNA. Translation: AAH00622.1.
BC043349 mRNA. Translation: AAH43349.1.
BC063041 mRNA. Translation: AAH63041.1.
CCDSiCCDS41955.1. [O75717-2]
CCDS9721.1. [O75717-1]
RefSeqiNP_001008397.1. NM_001008396.2. [O75717-2]
NP_009017.1. NM_007086.3. [O75717-1]
UniGeneiHs.385998.

Genome annotation databases

EnsembliENST00000360586; ENSP00000353793; ENSG00000198554.
ENST00000420358; ENSP00000399349; ENSG00000198554.
ENST00000421192; ENSP00000391049; ENSG00000198554.
GeneIDi11169.
KEGGihsa:11169.
UCSCiuc001xbm.2. human. [O75717-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ006266 mRNA. Translation: CAA06932.1 .
AL160471 Genomic DNA. No translation available.
BC000622 mRNA. Translation: AAH00622.1 .
BC043349 mRNA. Translation: AAH43349.1 .
BC063041 mRNA. Translation: AAH63041.1 .
CCDSi CCDS41955.1. [O75717-2 ]
CCDS9721.1. [O75717-1 ]
RefSeqi NP_001008397.1. NM_001008396.2. [O75717-2 ]
NP_009017.1. NM_007086.3. [O75717-1 ]
UniGenei Hs.385998.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
2D7L NMR - A 1017-1084 [» ]
ProteinModelPortali O75717.
SMRi O75717. Positions 11-284, 1017-1084.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 116340. 30 interactions.
IntActi O75717. 2 interactions.
STRINGi 9606.ENSP00000353793.

PTM databases

PhosphoSitei O75717.

Proteomic databases

MaxQBi O75717.
PaxDbi O75717.
PRIDEi O75717.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000360586 ; ENSP00000353793 ; ENSG00000198554 .
ENST00000420358 ; ENSP00000399349 ; ENSG00000198554 .
ENST00000421192 ; ENSP00000391049 ; ENSG00000198554 .
GeneIDi 11169.
KEGGi hsa:11169.
UCSCi uc001xbm.2. human. [O75717-1 ]

Organism-specific databases

CTDi 11169.
GeneCardsi GC14M055405.
HGNCi HGNC:23170. WDHD1.
HPAi HPA001122.
MIMi 608126. gene.
neXtProti NX_O75717.
PharmGKBi PA134988782.
GenAtlasi Search...

Phylogenomic databases

eggNOGi COG2319.
HOGENOMi HOG000015160.
HOVERGENi HBG074190.
InParanoidi O75717.
KOi K11274.
OMAi WTPICNT.
OrthoDBi EOG7J70F9.
PhylomeDBi O75717.
TreeFami TF105988.

Enzyme and pathway databases

SignaLinki O75717.

Miscellaneous databases

EvolutionaryTracei O75717.
GeneWikii WDHD1.
GenomeRNAii 11169.
NextBioi 42497.
PROi O75717.
SOURCEi Search...

Gene expression databases

ArrayExpressi O75717.
Bgeei O75717.
CleanExi HS_WDHD1.
Genevestigatori O75717.

Family and domain databases

Gene3Di 1.10.30.10. 1 hit.
2.130.10.10. 1 hit.
InterProi IPR022100. DUF3639.
IPR009071. HMG_box_dom.
IPR013979. TIF_beta_prop-like.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR019775. WD40_repeat_CS.
IPR017986. WD40_repeat_dom.
[Graphical view ]
Pfami PF12341. DUF3639. 1 hit.
PF08662. eIF2A. 1 hit.
PF00505. HMG_box. 1 hit.
PF00400. WD40. 2 hits.
[Graphical view ]
SMARTi SM00398. HMG. 1 hit.
SM00320. WD40. 5 hits.
[Graphical view ]
SUPFAMi SSF47095. SSF47095. 1 hit.
SSF50978. SSF50978. 1 hit.
PROSITEi PS50118. HMG_BOX_2. 1 hit.
PS00678. WD_REPEATS_1. 1 hit.
PS50082. WD_REPEATS_2. 3 hits.
PS50294. WD_REPEATS_REGION. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Koehler A.
    Submitted (MAY-1998) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
    Tissue: Fetal brain.
  2. "The DNA sequence and analysis of human chromosome 14."
    Heilig R., Eckenberg R., Petit J.-L., Fonknechten N., Da Silva C., Cattolico L., Levy M., Barbe V., De Berardinis V., Ureta-Vidal A., Pelletier E., Vico V., Anthouard V., Rowen L., Madan A., Qin S., Sun H., Du H.
    , Pepin K., Artiguenave F., Robert C., Cruaud C., Bruels T., Jaillon O., Friedlander L., Samson G., Brottier P., Cure S., Segurens B., Aniere F., Samain S., Crespeau H., Abbasi N., Aiach N., Boscus D., Dickhoff R., Dors M., Dubois I., Friedman C., Gouyvenoux M., James R., Madan A., Mairey-Estrada B., Mangenot S., Martins N., Menard M., Oztas S., Ratcliffe A., Shaffer T., Trask B., Vacherie B., Bellemere C., Belser C., Besnard-Gonnet M., Bartol-Mavel D., Boutard M., Briez-Silla S., Combette S., Dufosse-Laurent V., Ferron C., Lechaplais C., Louesse C., Muselet D., Magdelenat G., Pateau E., Petit E., Sirvain-Trukniewicz P., Trybou A., Vega-Czarny N., Bataille E., Bluet E., Bordelais I., Dubois M., Dumont C., Guerin T., Haffray S., Hammadi R., Muanga J., Pellouin V., Robert D., Wunderle E., Gauguet G., Roy A., Sainte-Marthe L., Verdier J., Verdier-Discala C., Hillier L.W., Fulton L., McPherson J., Matsuda F., Wilson R., Scarpelli C., Gyapay G., Wincker P., Saurin W., Quetier F., Waterston R., Hood L., Weissenbach J.
    Nature 421:601-607(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
    Tissue: Liver, Skin and Uterus.
  4. "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."
    Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P., Mann M.
    Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-374; SER-383 AND SER-868, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  5. "Mcm10 and And-1/CTF4 recruit DNA polymerase alpha to chromatin for initiation of DNA replication."
    Zhu W., Ukomadu C., Jha S., Senga T., Dhar S.K., Wohlschlegel J.A., Nutt L.K., Kornbluth S., Dutta A.
    Genes Dev. 21:2288-2299(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: INTERACTION WITH POLA1 AND MCM10.
  6. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-824, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Embryonic kidney.
  7. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-333; SER-383; SER-387; SER-868 AND SER-1090, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  8. "Assembly of the Cdc45-Mcm2-7-GINS complex in human cells requires the Ctf4/And-1, RecQL4, and Mcm10 proteins."
    Im J.S., Ki S.H., Farina A., Jung D.S., Hurwitz J., Lee J.K.
    Proc. Natl. Acad. Sci. U.S.A. 106:15628-15632(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION.
  9. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
    Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K., Rodionov V., Han D.K.
    Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-333; SER-374 AND SER-383, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Leukemic T-cell.
  10. "Lysine acetylation targets protein complexes and co-regulates major cellular functions."
    Choudhary C., Kumar C., Gnad F., Nielsen M.L., Rehman M., Walther T.C., Olsen J.V., Mann M.
    Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-962, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  11. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
    Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M.
    Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-333; SER-383 AND SER-387, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  12. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  13. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
    Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T., Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B.
    Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-374; SER-383; SER-868 AND SER-984, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  14. "Okazaki fragment processing-independent role for human Dna2 enzyme during DNA replication."
    Duxin J.P., Moore H.R., Sidorova J., Karanja K., Honaker Y., Dao B., Piwnica-Worms H., Campbell J.L., Monnat R.J. Jr., Stewart S.A.
    J. Biol. Chem. 287:21980-21991(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: INTERACTION WITH DNA2.
  15. "Solution structure of the HMG box domain from human WD repeat and HMG-box DNA binding protein 1."
    RIKEN structural genomics initiative (RSGI)
    Submitted (MAY-2006) to the PDB data bank
    Cited for: STRUCTURE BY NMR OF 1017-1084.

Entry informationi

Entry nameiWDHD1_HUMAN
AccessioniPrimary (citable) accession number: O75717
Secondary accession number(s): C9JW18, F6W0U7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 22, 2003
Last sequence update: November 1, 1998
Last modified: September 3, 2014
This is version 131 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Human chromosome 14
    Human chromosome 14: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  6. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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