O75612 (O75612_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Submitted name: Bile salt-dependent lipase oncofetal isoform EMBL AAC71012.1
Organism	Homo sapiens (Human) EMBL AAC71012.1
Taxonomic identifier	9606 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	612 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Molecular function	Hydrolase RuleBase RU003418 SAAS SAAS019826
Gene Ontology (GO)
Biological_process	cell differentiation Non-traceable author statement Ref.1. Source: UniProtKB cell growth Non-traceable author statement Ref.1. Source: UniProtKB cholesterol catabolic process Non-traceable author statement Ref.1. Source: UniProtKB fat-soluble vitamin catabolic process Non-traceable author statement Ref.1. Source: UniProtKB intestinal cholesterol absorption Non-traceable author statement Ref.1. Source: UniProtKB
Cellular_component	Golgi apparatus Inferred from direct assay Ref.1. Source: UniProtKB endoplasmic reticulum Inferred from direct assay Ref.1. Source: UniProtKB
Molecular_function	lipase activity Traceable author statement Ref.1. Source: UniProtKB
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL AAC71012.1

Sequences

	Sequence		Length	Mass (Da)
	O75612 [UniParc]. Last modified November 1, 1998. Version 1. Checksum: A5E9092D19390B26	FASTA	612	66,363
	10 20 30 40 50 60 AKLGAVYTEG GFVEGVNKKL GLLGDSVDIF KGIPFAAPTK ALENPQPHPG WQGTLKAKNF 70 80 90 100 110 120 KKRCLQATIT QDSTYGDEDC LYLNIWVPQG RKQVSRDLPV MIWIYGGAFL MGSGHGANFL 130 140 150 160 170 180 NNYLYDGEEI ATRGNVIVVT FNYRVGPLGF LSTGDANLPG NYGLRDQHMA IAWVKRNIAA 190 200 210 220 230 240 FGGDPNNITL FGESAGGASV SLQTLSPYNK GLIRRAISQS GVALSPWVIQ KNPLFWAKKV 250 260 270 280 290 300 AEKVGCPVGD AARMAQCLKV TDPRALTLAY KVPLAGLEYP MLHYVGFVPV IDGDFIPADP 310 320 330 340 350 360 INLYANAADI DYIAGTNNMD GHIFASIDMP AINKGNKKVT EEDFYKLVSE FTITKGLRGA 370 380 390 400 410 420 KTTFDVYTES WAQDPSQENK KKTVVDFETD VLFLVPTEIA LAQHRANAKS AKTYAYLFSH 430 440 450 460 470 480 PSRMPVYPKW VGADHADDIQ YVFGKPFATP TGYRPQDRTV SKAMIAYWTN FAKTGDPNMG 490 500 510 520 530 540 DSAVPTHWEP YTTENSGYLE ITKKMGSSSM KRSLRTNFLR YWTLTYLALP TVTDQEATPV 550 560 570 580 590 600 PPTGDSEATP VPPTGDSETA PVPPTGDSGA PPVPPTGDSG APPVPPTGDS EAAPVPPTGD 610 SKEAQMPAVI RF

References

[1]	"Molecular cloning of the oncofetal isoform of the human pancreatic bile salt-dependent lipase." Pasqualini E., Caillol N., Panicot L., Mas E., Lloubes R., Lombardo D. J. Biol. Chem. 273:28208-28218(1998) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Tissue: Pancreas EMBL AAC71012.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF081673 mRNA. Translation: AAC71012.1.
IPI	IPI00099670.
RefSeq	NP_001798.2. NM_001807.4.
UniGene	Hs.533258.
3D structure databases
HSSP	HSSP built from PDB template 1F6W based on UniProtKB P19835.
ProteinModelPortal	O75612.
ModBase	Search...
Protein-protein interaction databases
STRING	O75612.
Proteomic databases
PRIDE	O75612.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1056.
Phylogenomic databases
HOGENOM	HOG000091866.
HOVERGEN	HBG008839.
Gene expression databases
ArrayExpress	O75612.
Family and domain databases
InterPro	IPR002018. CarbesteraseB. IPR019826. Carboxylesterase_B_AS. IPR019819. Carboxylesterase_B_CS. [Graphical view]
Pfam	PF00135. COesterase. 1 hit. [Graphical view]
PROSITE	PS00122. CARBOXYLESTERASE_B_1. 1 hit. PS00941. CARBOXYLESTERASE_B_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

O75612_HUMAN

Accession

Primary (citable) accession number: O75612

Entry history

Integrated into UniProtKB/TrEMBL:	November 1, 1998
Last sequence update:	November 1, 1998
Last modified:	April 3, 2013
This is version 68 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.