O75276 (O75276_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
PKD1 EMBL AAC34211.1

Gene names

Name:

PKD1 EMBL AAC34211.1

Organism

Homo sapiens (Human) EMBL AAC34211.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	1339 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Contains 1 GPS domain. SAAS SAAS000203

Ontologies

Keywords
Cellular component	Membrane
Domain	Transmembrane Transmembrane helix SAAS SAAS000203
Gene Ontology (GO)
Biological process	neuropeptide signaling pathway Inferred from electronic annotation. Source: InterPro
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL AAC34211.1

Sequences

	Sequence		Length	Mass (Da)
	O75276 [UniParc]. Last modified November 1, 1998. Version 1. Checksum: 8C30F58A3ED2B891	FASTA	1,339	147,096
	10 20 30 40 50 60 PESLQGADHR PYTFFISPGS RDPAGSYHLN LSSHFRWSAL QVSVGLYTSL CQYFSEEDMV 70 80 90 100 110 120 WRTEGLLPLE ETSPRQAVCL TRHLTAFGAS LFVPPSHVRF VFPEPTADVN YIVMLTCAVC 130 140 150 160 170 180 LVTYMVMAAI LHKLDQLDAS RGRAIPFCGQ RGRFKYEILV KTGWGRGSGT TAHVGIMLYG 190 200 210 220 230 240 VDSRSGHRHL DGDRAFHRNS LDIFRIATPH SLGSVWKIRV WHDNKGLSPA WFLQHVIVRD 250 260 270 280 290 300 LQTARSAFFL VNDWLSVETE ANGGLVEKEV LAASDAALLR FRRLLVAELQ RGFFDKHIWL 310 320 330 340 350 360 SIWDRPPRSR FTRIQRATCC VLLICLFLGA NAVWYGAVGD SAYSTGHVSR LSPLSVDTVA 370 380 390 400 410 420 VGLVSSVVVY PVYLAILFLF RMSRSKVAGS PSPTPAGQQV LDIDSCLDSS VLDSSFLTFS 430 440 450 460 470 480 GLHAEQAFVG QMKSDLFLDD SKSLVCWPSG EGTLSWPDLL SDPSIVGSNL RQLARGQAGH 490 500 510 520 530 540 GLGPEEDGFS LASPYSPAKS FSASDEDLIQ QVLAEGVSSP APTQDTHMET DLLSSLSSTP 550 560 570 580 590 600 GEKTETLALQ RLGELGPPSP GLNWEQPQAA RLSRTGLVEG LRKRLLPAWC ASLAHGLSLL 610 620 630 640 650 660 LVAVAVAVSG WVGASFPPGV SVAWLLSSSA SFLASFLGWE PLKVLLEALY FSLVAKRLHP 670 680 690 700 710 720 DEDDTLVESP AVTPVSARVP RVRPPHGFAL FLAKEEARKV KRLHGMLRSL LVYMLFLLVT 730 740 750 760 770 780 LLASYGDASC HGHAYRLQSA IKQELHSRAF LAITRSEELW PWMAHVLLPY VHGNQSSPEL 790 800 810 820 830 840 GPPRLRQVRL QEALYPDPPG PRVHTCSAAG GFSTSDYDVG WESPHNGSGT WAYSAPDLLG 850 860 870 880 890 900 AWSWGSCAVY DSGGYVQELG LSLEESRDRL RFLQLHNWLD NRSRAVFLEL TRYSPAVGLH 910 920 930 940 950 960 AAVTLRLEFP AAGRALAALS VRPFALRRLS AGLSLPLLTS VCLLLFAVHF AVAEARTWHR 970 980 990 1000 1010 1020 EGRWRVLRLG AWARWLLVAL TAATALVRLA QLGAADRQWT RFVRGRPRRF TSFDQVAQLS 1030 1040 1050 1060 1070 1080 SAARGLAASL LFLLLVKAAQ QLRFVRQWSV FGKTLCRALP ELLGVTLGLV VLGVAYAQLA 1090 1100 1110 1120 1130 1140 ILLVSSCVDS LWSVAQALLV LCPGTGLSTL CPAESWHLSP LLCVGLWALR LWGALRLGAV 1150 1160 1170 1180 1190 1200 ILRWRYHALR GELYRPAWEP QDYEMVELFL RRLRLWMGLS KVKEFRHKVR FEGMEPLPSR 1210 1220 1230 1240 1250 1260 SSRGSKVSPD VPPPSAGSDA SHPSTSSSQL DGLSVSLGRL GTRCEPEPSR LQAVFEALLT 1270 1280 1290 1300 1310 1320 QFDRLNQATE DVYQLEQQLH SLQGRRSSRA PAGSSRGPSP GLRPALPSRL ARASRGVDLA 1330 TGPSRTPLRA KNKVHPSST

References

[1]	"Sequencing of Human Chromosome 16p13.3." Ricke D.O., Bruce D., Mundt M., Doggett N., Munk C., Saunders E., Robinson D., Jones M., Buckingham J., Chasteen L., Thompson S., Goodwin L., Bryant J., Tesmer J., Meincke L., Longmire J., White S., Ueng S. , Tatum O., Campbell C., Fawcett J., Maltbie M., Misra M., Deaven L. Submitted (SEP-1998) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[2]	"Large Scale Sequence Analysis and Annotation with the Sequence Comparison Analysis (SCAN) System." Ricke D.O. Submitted (SEP-1998) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC005600 Genomic DNA. Translation: AAC34211.1.
IPI	IPI00409566.
UniGene	Hs.75813.
3D structure databases
ProteinModelPortal	O75276.
ModBase	Search...
Protein-protein interaction databases
STRING	O75276.
Proteomic databases
PRIDE	O75276.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Phylogenomic databases
eggNOG	prNOG13172.
Gene expression databases
ArrayExpress	O75276.
Bgee	O75276.
Family and domain databases
InterPro	IPR000203. GPS_dom. IPR008976. Lipase_LipOase. IPR001024. LipOase_LH2. IPR013122. PKD1_2_channel. IPR000434. PKD_1. [Graphical view]
Gene3D	G3DSA:2.60.60.20. Lipase_LipOase. 1 hit.
Pfam	PF01825. GPS. 1 hit. PF08016. PKD_channel. 1 hit. PF01477. PLAT. 1 hit. [Graphical view]
PRINTS	PR00500. POLYCYSTIN1.
SMART	SM00303. GPS. 1 hit. SM00308. LH2. 1 hit. [Graphical view]
SUPFAM	SSF49723. Lipase_LipOase. 1 hit.
PROSITE	PS50221. GPS. 1 hit. PS50095. PLAT. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

O75276_HUMAN

Accession

Primary (citable) accession number: O75276

Entry history

Integrated into UniProtKB/TrEMBL:	November 1, 1998
Last sequence update:	November 1, 1998
Last modified:	November 16, 2011
This is version 67 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.