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O75200

- NPIB7_HUMAN

UniProt

O75200 - NPIB7_HUMAN

Protein

Nuclear pore complex-interacting protein family member B7

Gene

NPIPB7

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 77 (01 Oct 2014)
      Sequence version 3 (16 Oct 2013)
      Previous versions | rss
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    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Nuclear pore complex-interacting protein family member B7
    Alternative name(s):
    Nuclear pore complex-interacting protein-like 1
    Gene namesi
    Name:NPIPB7
    Synonyms:NPIPL1
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 16

    Organism-specific databases

    HGNCiHGNC:33832. NPIPB7.

    Subcellular locationi

    Secreted Curated

    GO - Cellular componenti

    1. extracellular region Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Secreted

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 1818Sequence AnalysisAdd
    BLAST
    Chaini19 – 414396Nuclear pore complex-interacting protein family member B7PRO_0000326066Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Glycosylationi111 – 1111N-linked (GlcNAc...)Sequence Analysis

    Keywords - PTMi

    Glycoprotein

    Proteomic databases

    PaxDbiO75200.
    PRIDEiO75200.

    PTM databases

    PhosphoSiteiO75200.

    Expressioni

    Gene expression databases

    BgeeiE7ERT9.
    GenevestigatoriO75200.

    Organism-specific databases

    HPAiHPA026924.

    Structurei

    3D structure databases

    ProteinModelPortaliO75200.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi247 – 363117Pro-richAdd
    BLAST

    Sequence similaritiesi

    Belongs to the NPIP family.Curated

    Keywords - Domaini

    Coiled coil, Signal

    Phylogenomic databases

    eggNOGiNOG250343.
    HOGENOMiHOG000293160.
    HOVERGENiHBG052821.
    InParanoidiO75200.
    OMAiWRNVERK.
    PhylomeDBiO75200.
    TreeFamiTF333389.

    Family and domain databases

    InterProiIPR009443. NPIP.
    [Graphical view]
    PANTHERiPTHR15438. PTHR15438. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    O75200-1 [UniParc]FASTAAdd to Basket

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    MRLRFWLLIW LLLGFISHQP TPVINSLAVY RHRETDFGVG VRDHPGQHGK    50
    TPSPQKLDNL IIIIIGFLRR YTFNVLFCTS CLCVSFLKTI FWSRNGHDGS 100
    MDVQQRAWRS NRSRQKGLRS ICMHTKKRVS SFRGNKIGLK DVITLRRHVE 150
    TKVRAKIRKR KVTTKINRHD KINGKRKTAR KQKMFQRAQE LRRRAEDYHK 200
    CKIPPSARKP LCNWVRMAAA EHCHSSGLPY WLYLTAETLK NRMGRQPPPP 250
    TQQHSITDNS LSLKTPPECL LTPLPPSVDD NIKECPLAPL PPSPLPPSVD 300
    DNLKECLFVP LPPSPLPPSV DDNLKECLFV PLPPSPLPPS VDDNLKTPPL 350
    ATQEAEVEKP PKPKRWRVDE VEQSPKPKRQ REAEAQQLPK PKRRRLSKLR 400
    TRHCTQAWAI RINP 414
    Length:414
    Mass (Da):47,714
    Last modified:October 16, 2013 - v3
    Checksum:i34224B51C5C6E2F7
    GO

    Sequence cautioni

    The sequence AAC27429.1 differs from that shown. Reason: Erroneous gene model prediction.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC002544 Genomic DNA. Translation: AAC27429.1. Sequence problems.
    AC138894 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENST00000452313; ENSP00000405348; ENSG00000233232.
    UCSCiuc002dpe.2. human.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC002544 Genomic DNA. Translation: AAC27429.1 . Sequence problems.
    AC138894 Genomic DNA. No translation available.

    3D structure databases

    ProteinModelPortali O75200.
    ModBasei Search...
    MobiDBi Search...

    PTM databases

    PhosphoSitei O75200.

    Proteomic databases

    PaxDbi O75200.
    PRIDEi O75200.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000452313 ; ENSP00000405348 ; ENSG00000233232 .
    UCSCi uc002dpe.2. human.

    Organism-specific databases

    H-InvDB HIX0038977.
    HGNCi HGNC:33832. NPIPB7.
    HPAi HPA026924.
    neXtProti NX_O75200.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG250343.
    HOGENOMi HOG000293160.
    HOVERGENi HBG052821.
    InParanoidi O75200.
    OMAi WRNVERK.
    PhylomeDBi O75200.
    TreeFami TF333389.

    Miscellaneous databases

    ChiTaRSi NPIPL1. human.
    NextBioi 35500089.
    PROi O75200.

    Gene expression databases

    Bgeei E7ERT9.
    Genevestigatori O75200.

    Family and domain databases

    InterProi IPR009443. NPIP.
    [Graphical view ]
    PANTHERi PTHR15438. PTHR15438. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. "The sequence and analysis of duplication-rich human chromosome 16."
      Martin J., Han C., Gordon L.A., Terry A., Prabhakar S., She X., Xie G., Hellsten U., Chan Y.M., Altherr M., Couronne O., Aerts A., Bajorek E., Black S., Blumer H., Branscomb E., Brown N.C., Bruno W.J.
      , Buckingham J.M., Callen D.F., Campbell C.S., Campbell M.L., Campbell E.W., Caoile C., Challacombe J.F., Chasteen L.A., Chertkov O., Chi H.C., Christensen M., Clark L.M., Cohn J.D., Denys M., Detter J.C., Dickson M., Dimitrijevic-Bussod M., Escobar J., Fawcett J.J., Flowers D., Fotopulos D., Glavina T., Gomez M., Gonzales E., Goodstein D., Goodwin L.A., Grady D.L., Grigoriev I., Groza M., Hammon N., Hawkins T., Haydu L., Hildebrand C.E., Huang W., Israni S., Jett J., Jewett P.B., Kadner K., Kimball H., Kobayashi A., Krawczyk M.-C., Leyba T., Longmire J.L., Lopez F., Lou Y., Lowry S., Ludeman T., Manohar C.F., Mark G.A., McMurray K.L., Meincke L.J., Morgan J., Moyzis R.K., Mundt M.O., Munk A.C., Nandkeshwar R.D., Pitluck S., Pollard M., Predki P., Parson-Quintana B., Ramirez L., Rash S., Retterer J., Ricke D.O., Robinson D.L., Rodriguez A., Salamov A., Saunders E.H., Scott D., Shough T., Stallings R.L., Stalvey M., Sutherland R.D., Tapia R., Tesmer J.G., Thayer N., Thompson L.S., Tice H., Torney D.C., Tran-Gyamfi M., Tsai M., Ulanovsky L.E., Ustaszewska A., Vo N., White P.S., Williams A.L., Wills P.L., Wu J.-R., Wu K., Yang J., DeJong P., Bruce D., Doggett N.A., Deaven L., Schmutz J., Grimwood J., Richardson P., Rokhsar D.S., Eichler E.E., Gilna P., Lucas S.M., Myers R.M., Rubin E.M., Pennacchio L.A.
      Nature 432:988-994(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

    Entry informationi

    Entry nameiNPIB7_HUMAN
    AccessioniPrimary (citable) accession number: O75200
    Secondary accession number(s): E7ERT9
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: March 18, 2008
    Last sequence update: October 16, 2013
    Last modified: October 1, 2014
    This is version 77 of the entry and version 3 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 16
      Human chromosome 16: entries, gene names and cross-references to MIM
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3