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O75200

- NPIB7_HUMAN

UniProt

O75200 - NPIB7_HUMAN

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Protein
Nuclear pore complex-interacting protein family member B7
Gene
NPIPB7, NPIPL1
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Names & Taxonomyi

Protein namesi
Recommended name:
Nuclear pore complex-interacting protein family member B7
Alternative name(s):
Nuclear pore complex-interacting protein-like 1
Gene namesi
Name:NPIPB7
Synonyms:NPIPL1
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 16

Organism-specific databases

HGNCiHGNC:33832. NPIPB7.

Subcellular locationi

Secreted Reviewed prediction

GO - Cellular componenti

  1. extracellular region Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1818 Reviewed prediction
Add
BLAST
Chaini19 – 414396Nuclear pore complex-interacting protein family member B7
PRO_0000326066Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi111 – 1111N-linked (GlcNAc...) Reviewed prediction

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiO75200.
PRIDEiO75200.

PTM databases

PhosphoSiteiO75200.

Expressioni

Gene expression databases

BgeeiE7ERT9.
GenevestigatoriO75200.

Organism-specific databases

HPAiHPA026924.

Structurei

3D structure databases

ProteinModelPortaliO75200.

Family & Domainsi

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi247 – 363117Pro-rich
Add
BLAST

Sequence similaritiesi

Belongs to the NPIP family.

Keywords - Domaini

Coiled coil, Signal

Phylogenomic databases

eggNOGiNOG250343.
HOGENOMiHOG000293160.
HOVERGENiHBG052821.
InParanoidiO75200.
OMAiWRNVERK.
PhylomeDBiO75200.
TreeFamiTF333389.

Family and domain databases

InterProiIPR009443. NPIP.
[Graphical view]
PANTHERiPTHR15438. PTHR15438. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

O75200-1 [UniParc]FASTAAdd to Basket

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MRLRFWLLIW LLLGFISHQP TPVINSLAVY RHRETDFGVG VRDHPGQHGK    50
TPSPQKLDNL IIIIIGFLRR YTFNVLFCTS CLCVSFLKTI FWSRNGHDGS 100
MDVQQRAWRS NRSRQKGLRS ICMHTKKRVS SFRGNKIGLK DVITLRRHVE 150
TKVRAKIRKR KVTTKINRHD KINGKRKTAR KQKMFQRAQE LRRRAEDYHK 200
CKIPPSARKP LCNWVRMAAA EHCHSSGLPY WLYLTAETLK NRMGRQPPPP 250
TQQHSITDNS LSLKTPPECL LTPLPPSVDD NIKECPLAPL PPSPLPPSVD 300
DNLKECLFVP LPPSPLPPSV DDNLKECLFV PLPPSPLPPS VDDNLKTPPL 350
ATQEAEVEKP PKPKRWRVDE VEQSPKPKRQ REAEAQQLPK PKRRRLSKLR 400
TRHCTQAWAI RINP 414
Length:414
Mass (Da):47,714
Last modified:October 16, 2013 - v3
Checksum:i34224B51C5C6E2F7
GO

Sequence cautioni

The sequence AAC27429.1 differs from that shown. Reason: Erroneous gene model prediction.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC002544 Genomic DNA. Translation: AAC27429.1. Sequence problems.
AC138894 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000452313; ENSP00000405348; ENSG00000233232.
UCSCiuc002dpe.2. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC002544 Genomic DNA. Translation: AAC27429.1 . Sequence problems.
AC138894 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortali O75200.
ModBasei Search...

PTM databases

PhosphoSitei O75200.

Proteomic databases

PaxDbi O75200.
PRIDEi O75200.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000452313 ; ENSP00000405348 ; ENSG00000233232 .
UCSCi uc002dpe.2. human.

Organism-specific databases

H-InvDB HIX0038977.
HGNCi HGNC:33832. NPIPB7.
HPAi HPA026924.
neXtProti NX_O75200.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG250343.
HOGENOMi HOG000293160.
HOVERGENi HBG052821.
InParanoidi O75200.
OMAi WRNVERK.
PhylomeDBi O75200.
TreeFami TF333389.

Miscellaneous databases

ChiTaRSi NPIPL1. human.
NextBioi 35500089.
PROi O75200.

Gene expression databases

Bgeei E7ERT9.
Genevestigatori O75200.

Family and domain databases

InterProi IPR009443. NPIP.
[Graphical view ]
PANTHERi PTHR15438. PTHR15438. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. "The sequence and analysis of duplication-rich human chromosome 16."
    Martin J., Han C., Gordon L.A., Terry A., Prabhakar S., She X., Xie G., Hellsten U., Chan Y.M., Altherr M., Couronne O., Aerts A., Bajorek E., Black S., Blumer H., Branscomb E., Brown N.C., Bruno W.J.
    , Buckingham J.M., Callen D.F., Campbell C.S., Campbell M.L., Campbell E.W., Caoile C., Challacombe J.F., Chasteen L.A., Chertkov O., Chi H.C., Christensen M., Clark L.M., Cohn J.D., Denys M., Detter J.C., Dickson M., Dimitrijevic-Bussod M., Escobar J., Fawcett J.J., Flowers D., Fotopulos D., Glavina T., Gomez M., Gonzales E., Goodstein D., Goodwin L.A., Grady D.L., Grigoriev I., Groza M., Hammon N., Hawkins T., Haydu L., Hildebrand C.E., Huang W., Israni S., Jett J., Jewett P.B., Kadner K., Kimball H., Kobayashi A., Krawczyk M.-C., Leyba T., Longmire J.L., Lopez F., Lou Y., Lowry S., Ludeman T., Manohar C.F., Mark G.A., McMurray K.L., Meincke L.J., Morgan J., Moyzis R.K., Mundt M.O., Munk A.C., Nandkeshwar R.D., Pitluck S., Pollard M., Predki P., Parson-Quintana B., Ramirez L., Rash S., Retterer J., Ricke D.O., Robinson D.L., Rodriguez A., Salamov A., Saunders E.H., Scott D., Shough T., Stallings R.L., Stalvey M., Sutherland R.D., Tapia R., Tesmer J.G., Thayer N., Thompson L.S., Tice H., Torney D.C., Tran-Gyamfi M., Tsai M., Ulanovsky L.E., Ustaszewska A., Vo N., White P.S., Williams A.L., Wills P.L., Wu J.-R., Wu K., Yang J., DeJong P., Bruce D., Doggett N.A., Deaven L., Schmutz J., Grimwood J., Richardson P., Rokhsar D.S., Eichler E.E., Gilna P., Lucas S.M., Myers R.M., Rubin E.M., Pennacchio L.A.
    Nature 432:988-994(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Entry informationi

Entry nameiNPIB7_HUMAN
AccessioniPrimary (citable) accession number: O75200
Secondary accession number(s): E7ERT9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 18, 2008
Last sequence update: October 16, 2013
Last modified: July 9, 2014
This is version 76 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 16
    Human chromosome 16: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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