Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

O75200 (NPIB7_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 74. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Nuclear pore complex-interacting protein family member B7
Alternative name(s):
Nuclear pore complex-interacting protein-like 1
Gene names
Name:NPIPB7
Synonyms:NPIPL1
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length414 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Subcellular location

Secreted Potential.

Sequence similarities

Belongs to the NPIP family.

Sequence caution

The sequence AAC27429.1 differs from that shown. Reason: Erroneous gene model prediction.

Ontologies

Keywords
   Cellular componentSecreted
   DomainCoiled coil
Signal
   PTMGlycoprotein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentextracellular region

Inferred from electronic annotation. Source: UniProtKB-SubCell

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 1818 Potential
Chain19 – 414396Nuclear pore complex-interacting protein family member B7
PRO_0000326066

Regions

Compositional bias247 – 363117Pro-rich

Amino acid modifications

Glycosylation1111N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
O75200 [UniParc].

Last modified October 16, 2013. Version 3.
Checksum: 34224B51C5C6E2F7

FASTA41447,714
        10         20         30         40         50         60 
MRLRFWLLIW LLLGFISHQP TPVINSLAVY RHRETDFGVG VRDHPGQHGK TPSPQKLDNL 

        70         80         90        100        110        120 
IIIIIGFLRR YTFNVLFCTS CLCVSFLKTI FWSRNGHDGS MDVQQRAWRS NRSRQKGLRS 

       130        140        150        160        170        180 
ICMHTKKRVS SFRGNKIGLK DVITLRRHVE TKVRAKIRKR KVTTKINRHD KINGKRKTAR 

       190        200        210        220        230        240 
KQKMFQRAQE LRRRAEDYHK CKIPPSARKP LCNWVRMAAA EHCHSSGLPY WLYLTAETLK 

       250        260        270        280        290        300 
NRMGRQPPPP TQQHSITDNS LSLKTPPECL LTPLPPSVDD NIKECPLAPL PPSPLPPSVD 

       310        320        330        340        350        360 
DNLKECLFVP LPPSPLPPSV DDNLKECLFV PLPPSPLPPS VDDNLKTPPL ATQEAEVEKP 

       370        380        390        400        410 
PKPKRWRVDE VEQSPKPKRQ REAEAQQLPK PKRRRLSKLR TRHCTQAWAI RINP 

« Hide

References

[1]"Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q."
Loftus B.J., Kim U.-J., Sneddon V.P., Kalush F., Brandon R., Fuhrmann J., Mason T., Crosby M.L., Barnstead M., Cronin L., Mays A.D., Cao Y., Xu R.X., Kang H.-L., Mitchell S., Eichler E.E., Harris P.C., Venter J.C., Adams M.D.
Genomics 60:295-308(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]"The sequence and analysis of duplication-rich human chromosome 16."
Martin J., Han C., Gordon L.A., Terry A., Prabhakar S., She X., Xie G., Hellsten U., Chan Y.M., Altherr M., Couronne O., Aerts A., Bajorek E., Black S., Blumer H., Branscomb E., Brown N.C., Bruno W.J. expand/collapse author list , Buckingham J.M., Callen D.F., Campbell C.S., Campbell M.L., Campbell E.W., Caoile C., Challacombe J.F., Chasteen L.A., Chertkov O., Chi H.C., Christensen M., Clark L.M., Cohn J.D., Denys M., Detter J.C., Dickson M., Dimitrijevic-Bussod M., Escobar J., Fawcett J.J., Flowers D., Fotopulos D., Glavina T., Gomez M., Gonzales E., Goodstein D., Goodwin L.A., Grady D.L., Grigoriev I., Groza M., Hammon N., Hawkins T., Haydu L., Hildebrand C.E., Huang W., Israni S., Jett J., Jewett P.B., Kadner K., Kimball H., Kobayashi A., Krawczyk M.-C., Leyba T., Longmire J.L., Lopez F., Lou Y., Lowry S., Ludeman T., Manohar C.F., Mark G.A., McMurray K.L., Meincke L.J., Morgan J., Moyzis R.K., Mundt M.O., Munk A.C., Nandkeshwar R.D., Pitluck S., Pollard M., Predki P., Parson-Quintana B., Ramirez L., Rash S., Retterer J., Ricke D.O., Robinson D.L., Rodriguez A., Salamov A., Saunders E.H., Scott D., Shough T., Stallings R.L., Stalvey M., Sutherland R.D., Tapia R., Tesmer J.G., Thayer N., Thompson L.S., Tice H., Torney D.C., Tran-Gyamfi M., Tsai M., Ulanovsky L.E., Ustaszewska A., Vo N., White P.S., Williams A.L., Wills P.L., Wu J.-R., Wu K., Yang J., DeJong P., Bruce D., Doggett N.A., Deaven L., Schmutz J., Grimwood J., Richardson P., Rokhsar D.S., Eichler E.E., Gilna P., Lucas S.M., Myers R.M., Rubin E.M., Pennacchio L.A.
Nature 432:988-994(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AC002544 Genomic DNA. Translation: AAC27429.1. Sequence problems.
AC138894 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortalO75200.
ModBaseSearch...
MobiDBSearch...

PTM databases

PhosphoSiteO75200.

Proteomic databases

PaxDbO75200.
PRIDEO75200.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000452313; ENSP00000405348; ENSG00000233232.
UCSCuc002dpe.2. human.

Organism-specific databases

H-InvDBHIX0038977.
HGNCHGNC:33832. NPIPB7.
HPAHPA026924.
neXtProtNX_O75200.
GenAtlasSearch...

Phylogenomic databases

eggNOGNOG250343.
HOGENOMHOG000293160.
HOVERGENHBG052821.
InParanoidO75200.
TreeFamTF333389.

Gene expression databases

BgeeE7ERT9.
GenevestigatorO75200.

Family and domain databases

InterProIPR009443. NPIP.
[Graphical view]
PANTHERPTHR15438. PTHR15438. 1 hit.
ProtoNetSearch...

Other

ChiTaRSNPIPL1. human.
NextBio35500089.
PROO75200.

Entry information

Entry nameNPIB7_HUMAN
AccessionPrimary (citable) accession number: O75200
Secondary accession number(s): E7ERT9
Entry history
Integrated into UniProtKB/Swiss-Prot: March 18, 2008
Last sequence update: October 16, 2013
Last modified: April 16, 2014
This is version 74 of the entry and version 3 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

SIMILARITY comments

Index of protein domains and families

Human chromosome 16

Human chromosome 16: entries, gene names and cross-references to MIM