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Reviewed, UniProtKB/Swiss-Prot O75177 (S18L1_HUMAN)

Last modified November 25, 2008. Version 60. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Web resources · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    SS18-like protein 1
Alternative name(s):
    SYT homolog 1
Gene names
Name: SS18L1
Synonyms: KIAA0693
OrganismHomo sapiens (Human)
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

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Protein attributes

Sequence length396 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceEvidence at protein level.

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General annotation (Comments)

Tissue specificity

Ubiquitous; with lowest levels in spleen.

Sequence similarities

Belongs to the SS18 family.

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Ontologies

Keywords

   DomainRepeat

Gene Ontology (GO)

   Molecular functionprotein binding

Inferred from direct assay. Source: MGI

Complete GO annotation...

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 396396SS18-like protein 1
PRO_0000181825

Regions

Motif50 – 534SH2-binding Potential
Motif353 – 3564SH2-binding Potential
Motif371 – 3799SH3-binding Potential
Motif391 – 3944SH2-binding Potential
Compositional bias190 – 396207Gln-rich

Experimental info

Sequence conflict1891M → I in AAH34494. Ref.3

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Sequences

Sequence LengthMass (Da)Tools
O75177-1 [UniParc].

Last modified January 31, 2002. Version 2.
Checksum: B76B7D61C7DF5592

FASTA39642,990
        10         20         30         40         50         60 
MSVAFASARP RGKGEVTQQT IQKMLDENHH LIQCILEYQS KGKTAECTQY QQILHRNLVY 

        70         80         90        100        110        120 
LATIADSNQN MQSLLPAPPT QNMNLGPGAL TQSGSSQGLH SQGSLSDAIS TGLPPSSLLQ 

       130        140        150        160        170        180 
GQIGNGPSHV SMQQTAPNTL PTTSMSISGP GYSHAGPASQ GVPMQGQGTI GNYVSRTNIN 

       190        200        210        220        230        240 
MQSNPVSMMQ QQAATSHYSS AQGGSQHYQG QSSIAMMGQG SQGSSMMGQR PMAPYRPSQQ 

       250        260        270        280        290        300 
GSSQQYLGQE EYYGEQYSHS QGAAEPMGQQ YYPDGHGDYA YQQSSYTEQS YDRSFEESTQ 

       310        320        330        340        350        360 
HYYEGGNSQY SQQQAGYQQG AAQQQTYSQQ QYPSQQSYPG QQQGYGSAQG APSQYPGYQQ 

       370        380        390 
GQGQQYGSYR APQTAPSAQQ QRPYGYEQGQ YGNYQQ

« Hide

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References

[1]"Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro."
Ishikawa K., Nagase T., Suyama M., Miyajima N., Tanaka A., Kotani H., Nomura N., Ohara O.
DNA Res. 5:169-176(1998) [PubMed: 9734811] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Brain.
[2]"The DNA sequence and comparative analysis of human chromosome 20."
Deloukas P., Matthews L.H., Ashurst J.L., Burton J., Gilbert J.G.R., Jones M., Stavrides G., Almeida J.P., Babbage A.K., Bagguley C.L., Bailey J., Barlow K.F., Bates K.N., Beard L.M., Beare D.M., Beasley O.P., Bird C.P., Blakey S.E. expand/collapse author list , Bridgeman A.M., Brown A.J., Buck D., Burrill W.D., Butler A.P., Carder C., Carter N.P., Chapman J.C., Clamp M., Clark G., Clark L.N., Clark S.Y., Clee C.M., Clegg S., Cobley V.E., Collier R.E., Connor R.E., Corby N.R., Coulson A., Coville G.J., Deadman R., Dhami P.D., Dunn M., Ellington A.G., Frankland J.A., Fraser A., French L., Garner P., Grafham D.V., Griffiths C., Griffiths M.N.D., Gwilliam R., Hall R.E., Hammond S., Harley J.L., Heath P.D., Ho S., Holden J.L., Howden P.J., Huckle E., Hunt A.R., Hunt S.E., Jekosch K., Johnson C.M., Johnson D., Kay M.P., Kimberley A.M., King A., Knights A., Laird G.K., Lawlor S., Lehvaeslaiho M.H., Leversha M.A., Lloyd C., Lloyd D.M., Lovell J.D., Marsh V.L., Martin S.L., McConnachie L.J., McLay K., McMurray A.A., Milne S.A., Mistry D., Moore M.J.F., Mullikin J.C., Nickerson T., Oliver K., Parker A., Patel R., Pearce T.A.V., Peck A.I., Phillimore B.J.C.T., Prathalingam S.R., Plumb R.W., Ramsay H., Rice C.M., Ross M.T., Scott C.E., Sehra H.K., Shownkeen R., Sims S., Skuce C.D., Smith M.L., Soderlund C., Steward C.A., Sulston J.E., Swann R.M., Sycamore N., Taylor R., Tee L., Thomas D.W., Thorpe A., Tracey A., Tromans A.C., Vaudin M., Wall M., Wallis J.M., Whitehead S.L., Whittaker P., Willey D.L., Williams L., Williams S.A., Wilming L., Wray P.W., Hubbard T., Durbin R.M., Bentley D.R., Beck S., Rogers J.
Nature 414:865-871(2001) [PubMed: 11780052] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[3]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Testis.
+Additional computationally mapped references.

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Cross-references

Sequence databases

AB014593 mRNA. Translation: BAA31668.1. Different initiation.
AL078633 Genomic DNA. Translation: CAI18836.1.
BC034494 mRNA. Translation: AAH34494.1.
RefSeqNP_945173.1.
UniGeneHs.154429

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

IntActO75177.

PTM databases

PhosphoSiteO75177.

Genome annotation databases

EnsemblENSG00000184402. Homo sapiens. [Contig view]
GeneID26039.
KEGGhsa:26039.

Organism-specific databases

HGNCHGNC:15592. SS18L1.
HPACAB011827.
MIM606472. gene.
PharmGKBPA37989.
HUGESearch...
GenAtlasSearch...
GeneCardsSearch...

Phylogenomic databases

HOVERGENO75177.

Gene expression databases

ArrayExpressO75177.
CleanExHS_SS18L1.
GermOnlineENSG00000184402. Homo sapiens.

Family and domain databases

InterProIPR007726. SSXT.
[Graphical view]
PANTHERPTHR23107. SSXT. 1 hit.
PfamPF05030. SSXT. 1 hit.
[Graphical view]
ProtoNetSearch...

Other Resources

LinkHubO75177.
NextBio47867.
SOURCESearch...

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Entry information

Entry nameS18L1_HUMAN
AccessionPrimary (citable) accession number: O75177
Secondary accession number(s): Q5JXJ3 expand/collapse secondary AC list , Q8NE69, Q9BR55, Q9H4K6
Entry history
Integrated into UniProtKB/Swiss-Prot: January 31, 2002
Last sequence update: January 31, 2002
Last modified: November 25, 2008
This is version 60 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHPI (Human Proteome Initiative)

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Relevant documents

Human chromosome 20

Human chromosome 20: entries, gene names and cross-references to MIM

MIM cross-references

Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Web resources · Cross-references · Entry information · Relevant documents