Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Hexokinase

Gene

hxk1

Organism
Yarrowia lipolytica (Candida lipolytica)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

ATP + D-hexose = ADP + D-hexose 6-phosphate.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationSAAS annotation, Transferase

Keywords - Biological processi

GlycolysisUniRule annotationSAAS annotation

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
HexokinaseUniRule annotation (EC:2.7.1.1UniRule annotation)
Gene namesi
Name:hxk1Imported
OrganismiYarrowia lipolytica (Candida lipolytica)Imported
Taxonomic identifieri4952 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDipodascaceaeYarrowia

PTM / Processingi

Proteomic databases

PRIDEiO74996.

Interactioni

Protein-protein interaction databases

STRINGi4952.XP_501216.1.

Structurei

3D structure databases

ProteinModelPortaliO74996.
SMRiO74996. Positions 18-527.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the hexokinase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG5026.
HOGENOMiHOG000162670.
PhylomeDBiO74996.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR019807. Hexokinase_BS.
IPR022673. Hexokinase_C.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 2 hits.
PF03727. Hexokinase_2. 1 hit.
[Graphical view]
PROSITEiPS00378. HEXOKINASE_1. 1 hit.
PS51748. HEXOKINASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O74996-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVHLGPRKPP SRKGSMADVP RDLLEQISQL ETIFTVSPEK LRQITDHFVS
60 70 80 90 100
ELAKGLTKEG GDIPMNPTWI LGWPTGKESG CYLALDMGGT NLRVVKVTLD
110 120 130 140 150
GDRGFDVMQS KYHMPPNIKV GKQEELWEYI AECLGKFLAD NYPEALDAHE
160 170 180 190 200
RGRDVDRTAA QSFTRDKSPP PHNQHISCSP GFDIHKIPLG FTFSYPCSQP
210 220 230 240 250
AVNRGVLQRW TKGFDIEGVE GEDVVPMLEA ALERKNIPIS ITALINDTTG
260 270 280 290 300
TMVASNYHDP QIKLGNIFGT GVNAAYYEKV KDIPKLKGLI PDSIDPETPM
310 320 330 340 350
AVNCEYGAFD NEHKVLPRTK WDIIIDEESP RPGQQTFEKM SAGYYLGELL
360 370 380 390 400
RLVLLDLYKD GFVFENQGKN GQELGNGNIN KSYFFDTSFL SLIEEDPWEN
410 420 430 440 450
LTDVEILFKE KLGINTTEPE RKLIRRLAEL IGTRSARISA CGVAAICKKA
460 470 480 490 500
GYKEAHAGAD GSVFNKYPGF KERGAQALNE IFEWNLPNPK DHPIKIVPAE
510 520 530
DGSGVGAALC AALTIKRVKQ GLPVGVKPGV KYDI
Length:534
Mass (Da):59,174
Last modified:November 1, 1998 - v1
Checksum:iF51F75E03EE2600E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ011524 mRNA. Translation: CAA09674.1.
AJ011525 Genomic DNA. Translation: CAA09675.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ011524 mRNA. Translation: CAA09674.1.
AJ011525 Genomic DNA. Translation: CAA09675.1.

3D structure databases

ProteinModelPortaliO74996.
SMRiO74996. Positions 18-527.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi4952.XP_501216.1.

Proteomic databases

PRIDEiO74996.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiCOG5026.
HOGENOMiHOG000162670.
PhylomeDBiO74996.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR019807. Hexokinase_BS.
IPR022673. Hexokinase_C.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 2 hits.
PF03727. Hexokinase_2. 1 hit.
[Graphical view]
PROSITEiPS00378. HEXOKINASE_1. 1 hit.
PS51748. HEXOKINASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Molecular cloning and characterization of the gene HXK1 encoding the hexokinase from Yarrowia lipolytica."
    Petit T., Gancedo C.
    Yeast 15:1573-1584(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiO74996_YARLL
AccessioniPrimary (citable) accession number: O74996
Secondary accession number(s): Q6CDP6
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1998
Last sequence update: November 1, 1998
Last modified: July 22, 2015
This is version 93 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.