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O74988

- COX5_SCHPO

UniProt

O74988 - COX5_SCHPO

Protein

Cytochrome c oxidase polypeptide 5, mitochondrial

Gene

cox5

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 92 (01 Oct 2014)
      Sequence version 2 (11 Jul 2012)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

    GO - Molecular functioni

    1. cytochrome-c oxidase activity Source: PomBase

    GO - Biological processi

    1. hydrogen ion transmembrane transport Source: GOC
    2. mitochondrial electron transport, cytochrome c to oxygen Source: PomBase

    Keywords - Molecular functioni

    Oxidoreductase

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Cytochrome c oxidase polypeptide 5, mitochondrial (EC:1.9.3.1)
    Alternative name(s):
    Cytochrome c oxidase polypeptide V
    Gene namesi
    Name:cox5
    ORF Names:SPCC338.10c
    OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
    Taxonomic identifieri284812 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
    ProteomesiUP000002485: Chromosome III

    Organism-specific databases

    PomBaseiSPCC338.10c.

    Subcellular locationi

    Mitochondrion inner membrane 1 Publication

    GO - Cellular componenti

    1. mitochondrial respiratory chain complex IV Source: PomBase
    2. mitochondrion Source: PomBase

    Keywords - Cellular componenti

    Membrane, Mitochondrion, Mitochondrion inner membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transit peptidei1 – 2020MitochondrionSequence AnalysisAdd
    BLAST
    Chaini21 – 186166Cytochrome c oxidase polypeptide 5, mitochondrialPRO_0000006096Add
    BLAST

    Proteomic databases

    MaxQBiO74988.
    PaxDbiO74988.

    Interactioni

    Subunit structurei

    Cytochrome c oxidase is composed of at least 11 subunits.By similarity

    Protein-protein interaction databases

    MINTiMINT-4682282.
    STRINGi4896.SPCC338.10c-1.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the cytochrome c oxidase IV family.Curated

    Keywords - Domaini

    Transit peptide

    Phylogenomic databases

    eggNOGiNOG263759.
    HOGENOMiHOG000175160.
    KOiK02263.
    OrthoDBiEOG7JHMJ1.

    Family and domain databases

    Gene3Di1.10.442.10. 1 hit.
    InterProiIPR004203. Cyt_c_oxidase_su4_fam.
    [Graphical view]
    PfamiPF02936. COX4. 1 hit.
    [Graphical view]
    SUPFAMiSSF81406. SSF81406. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    O74988-1 [UniParc]FASTAAdd to Basket

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    MYLSKIICKK VPMKLLCTRN AATVSAAATN ALQKEQPSGE AMIARPRLVD    50
    LDKRWGIMSQ EEKDGLITDL YARQKQPWTT LSIEEKKAAY WIAFGEHGPR 100
    AFSHISQKTV FWGTVAGLTI GVVLFGLIRT QAAPSPRTMT REWQEKSNEY 150
    MKENKINPIS GEASEGFKGR GQISGGIFSP SEKDKK 186
    Length:186
    Mass (Da):20,735
    Last modified:July 11, 2012 - v2
    Checksum:i19202F28597BE9CC
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CU329672 Genomic DNA. Translation: CAA19341.2.
    PIRiT41733.
    RefSeqiNP_588158.2. NM_001023147.2.

    Genome annotation databases

    EnsemblFungiiSPCC338.10c.1; SPCC338.10c.1:pep; SPCC338.10c.
    GeneIDi2538862.
    KEGGispo:SPCC338.10c.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CU329672 Genomic DNA. Translation: CAA19341.2 .
    PIRi T41733.
    RefSeqi NP_588158.2. NM_001023147.2.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    MINTi MINT-4682282.
    STRINGi 4896.SPCC338.10c-1.

    Proteomic databases

    MaxQBi O74988.
    PaxDbi O74988.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii SPCC338.10c.1 ; SPCC338.10c.1:pep ; SPCC338.10c .
    GeneIDi 2538862.
    KEGGi spo:SPCC338.10c.

    Organism-specific databases

    PomBasei SPCC338.10c.

    Phylogenomic databases

    eggNOGi NOG263759.
    HOGENOMi HOG000175160.
    KOi K02263.
    OrthoDBi EOG7JHMJ1.

    Miscellaneous databases

    NextBioi 20800043.

    Family and domain databases

    Gene3Di 1.10.442.10. 1 hit.
    InterProi IPR004203. Cyt_c_oxidase_su4_fam.
    [Graphical view ]
    Pfami PF02936. COX4. 1 hit.
    [Graphical view ]
    SUPFAMi SSF81406. SSF81406. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "The genome sequence of Schizosaccharomyces pombe."
      Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.
      , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
      Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 972 / ATCC 24843.
    2. "Comparative functional genomics of the fission yeasts."
      Rhind N., Chen Z., Yassour M., Thompson D.A., Haas B.J., Habib N., Wapinski I., Roy S., Lin M.F., Heiman D.I., Young S.K., Furuya K., Guo Y., Pidoux A., Chen H.M., Robbertse B., Goldberg J.M., Aoki K.
      , Bayne E.H., Berlin A.M., Desjardins C.A., Dobbs E., Dukaj L., Fan L., FitzGerald M.G., French C., Gujja S., Hansen K., Keifenheim D., Levin J.Z., Mosher R.A., Mueller C.A., Pfiffner J., Priest M., Russ C., Smialowska A., Swoboda P., Sykes S.M., Vaughn M., Vengrova S., Yoder R., Zeng Q., Allshire R., Baulcombe D., Birren B.W., Brown W., Ekwall K., Kellis M., Leatherwood J., Levin H., Margalit H., Martienssen R., Nieduszynski C.A., Spatafora J.W., Friedman N., Dalgaard J.Z., Baumann P., Niki H., Regev A., Nusbaum C.
      Science 332:930-936(2011) [PubMed] [Europe PMC] [Abstract]
      Cited for: REVISION OF GENE MODEL.
    3. "ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe."
      Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S., Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S., Yoshida M.
      Nat. Biotechnol. 24:841-847(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].

    Entry informationi

    Entry nameiCOX5_SCHPO
    AccessioniPrimary (citable) accession number: O74988
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 3, 2002
    Last sequence update: July 11, 2012
    Last modified: October 1, 2014
    This is version 92 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Schizosaccharomyces pombe
      Schizosaccharomyces pombe: entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3