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Protein

U1 small nuclear ribonucleoprotein usp102

Gene

usp102

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

Involved in nuclear mRNA splicing.By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein

Keywords - Biological processi

mRNA processing, mRNA splicing

Keywords - Ligandi

RNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
U1 small nuclear ribonucleoprotein usp102
Short name:
U1 snRNP protein usp102
Gene namesi
Name:usp102Imported
Synonyms:mud1Imported
ORF Names:SPBC4B4.07c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome II

Organism-specific databases

EuPathDBiFungiDB:SPBC4B4.07c.
PomBaseiSPBC4B4.07c. usp102.

Subcellular locationi

GO - Cellular componenti

  • nucleolus Source: PomBase
  • nucleus Source: PomBase
  • U1 snRNP Source: PomBase
  • U2-type prespliceosome Source: PomBase
Complete GO annotation...

Keywords - Cellular componenti

Nucleus, Spliceosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003384481 – 249U1 small nuclear ribonucleoprotein usp102Add BLAST249

Proteomic databases

MaxQBiO74968.
PRIDEiO74968.

Interactioni

Subunit structurei

Component of the spliceosome where it is associated with snRNP U1.1 Publication

Protein-protein interaction databases

BioGridi277382. 325 interactors.
MINTiMINT-4682144.

Structurei

3D structure databases

ProteinModelPortaliO74968.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini26 – 105RRM 1PROSITE-ProRule annotationAdd BLAST80
Domaini174 – 247RRM 2PROSITE-ProRule annotationAdd BLAST74

Sequence similaritiesi

Belongs to the RRM U1 A/B'' family.Sequence analysis
Contains 2 RRM (RNA recognition motif) domains.PROSITE-ProRule annotation

Keywords - Domaini

Repeat

Phylogenomic databases

HOGENOMiHOG000217519.
InParanoidiO74968.
OMAiENTNEVM.
OrthoDBiEOG092C5A64.
PhylomeDBiO74968.

Family and domain databases

Gene3Di3.30.70.330. 2 hits.
InterProiIPR012677. Nucleotide-bd_a/b_plait.
IPR000504. RRM_dom.
IPR024888. RRM_U1_A/B''.
[Graphical view]
PANTHERiPTHR10501. PTHR10501. 1 hit.
PfamiPF00076. RRM_1. 2 hits.
[Graphical view]
SMARTiSM00360. RRM. 2 hits.
[Graphical view]
SUPFAMiSSF54928. SSF54928. 2 hits.
PROSITEiPS50102. RRM. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O74968-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDPQTNSHQE VQQPSPKETD SQTPSETLYI RNIEEKIRLT MLKRILEHLF
60 70 80 90 100
GSYGKVIDVQ ARKTLRMRGQ AFVVFDNLEN ASRALKDLQG YPLYGKPMMI
110 120 130 140 150
QYSKSKSDII VQRESPEEIE TRKKDRKNRR EMLKRTSALQ PAAPKPTHKK
160 170 180 190 200
PVPKRNVGAE RKSTINEDLL PPNKVLLLQN IPQEVNADVL TQIFEAFSGF
210 220 230 240
QEVRMVPGRR GIAFVEYDSD REATVAKNGT TGMSLSGNQI KVTFARKAS
Length:249
Mass (Da):28,339
Last modified:November 1, 1998 - v1
Checksum:i44BCDC1B89A9037C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329671 Genomic DNA. Translation: CAA19287.1.
PIRiT40479.
RefSeqiNP_596424.1. NM_001022343.2.

Genome annotation databases

EnsemblFungiiSPBC4B4.07c.1; SPBC4B4.07c.1:pep; SPBC4B4.07c.
GeneIDi2540865.
KEGGispo:SPBC4B4.07c.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329671 Genomic DNA. Translation: CAA19287.1.
PIRiT40479.
RefSeqiNP_596424.1. NM_001022343.2.

3D structure databases

ProteinModelPortaliO74968.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi277382. 325 interactors.
MINTiMINT-4682144.

Proteomic databases

MaxQBiO74968.
PRIDEiO74968.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPBC4B4.07c.1; SPBC4B4.07c.1:pep; SPBC4B4.07c.
GeneIDi2540865.
KEGGispo:SPBC4B4.07c.

Organism-specific databases

EuPathDBiFungiDB:SPBC4B4.07c.
PomBaseiSPBC4B4.07c. usp102.

Phylogenomic databases

HOGENOMiHOG000217519.
InParanoidiO74968.
OMAiENTNEVM.
OrthoDBiEOG092C5A64.
PhylomeDBiO74968.

Miscellaneous databases

PROiO74968.

Family and domain databases

Gene3Di3.30.70.330. 2 hits.
InterProiIPR012677. Nucleotide-bd_a/b_plait.
IPR000504. RRM_dom.
IPR024888. RRM_U1_A/B''.
[Graphical view]
PANTHERiPTHR10501. PTHR10501. 1 hit.
PfamiPF00076. RRM_1. 2 hits.
[Graphical view]
SMARTiSM00360. RRM. 2 hits.
[Graphical view]
SUPFAMiSSF54928. SSF54928. 2 hits.
PROSITEiPS50102. RRM. 2 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRU1A_SCHPO
AccessioniPrimary (citable) accession number: O74968
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 10, 2008
Last sequence update: November 1, 1998
Last modified: November 30, 2016
This is version 111 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.