Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Peroxisomal ATPase pex1

Gene

pex1

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Component of the peroxisomal protein import machinery. Together with pex6, mediates the ATP-dependent relocation and recycling of the peroxisomal targeting signal-1 (PTS1) import receptor pex5 from the peroxisomal membrane to the cytosol, where it is then available for another round of protein import into the organelle (By similarity).By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi379 – 3868ATPSequence analysis
Nucleotide bindingi647 – 6548ATPSequence analysis

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Peroxisome biogenesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Peroxisomal ATPase pex1
Alternative name(s):
Peroxin-1
Peroxisome biogenesis protein pex1
Gene namesi
Name:pex1
ORF Names:SPCC553.03
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome III

Organism-specific databases

EuPathDBiFungiDB:SPCC553.03.
PomBaseiSPCC553.03. pex1.

Subcellular locationi

GO - Cellular componenti

  • cytoplasm Source: PomBase
  • cytosol Source: PomBase
  • peroxisomal membrane Source: UniProtKB-SubCell
  • peroxisome Source: PomBase
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Membrane, Peroxisome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 937937Peroxisomal ATPase pex1PRO_0000374017Add
BLAST

Proteomic databases

MaxQBiO74941.

Interactioni

Protein-protein interaction databases

BioGridi275970. 16 interactions.
MINTiMINT-4681950.

Structurei

3D structure databases

ProteinModelPortaliO74941.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the AAA ATPase family.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

InParanoidiO74941.
OrthoDBiEOG092C0WJM.
PhylomeDBiO74941.

Family and domain databases

Gene3Di3.10.330.10. 1 hit.
3.40.50.300. 2 hits.
InterProiIPR003593. AAA+_ATPase.
IPR003959. ATPase_AAA_core.
IPR029067. CDC48_domain_2-like.
IPR027417. P-loop_NTPase.
IPR015342. PEX-N_psi_beta-barrel.
IPR025653. Pex1.
[Graphical view]
PANTHERiPTHR23077:SF12. PTHR23077:SF12. 3 hits.
PfamiPF00004. AAA. 2 hits.
PF09262. PEX-1N. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 2 hits.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 3 hits.
SSF54585. SSF54585. 1 hit.

Sequencei

Sequence statusi: Complete.

O74941-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRCIVSYKSL RSCLVNVPEL LLESISEPVQ NYAVQAVVCK NDIKKTFYFG
60 70 80 90 100
ISGIPSQFSF EIDSTYAHTL KLAENQEINL SIIDCTHEIE QLEIEPVTSN
110 120 130 140 150
DWEIAERNAA WLEENLLVQY RVATTERFII YLPSGTFIQF QPLKLIPSSL
160 170 180 190 200
CGRLLRTTEV LITPKPNTSA IEVKENRKVN LRCVVENRLL PDSVTADSPA
210 220 230 240 250
LCVFLPLNFP DRPDVVYMDG GNLKSTIVCQ CVSCPFQIPG HFFISKSLAL
260 270 280 290 300
SYSIKTGFKF QIWKAHNPPS SSKFILEQKG LPPESNLSSE LVAAKLKNSY
310 320 330 340 350
LMDGMTLKLV DIAVSYSVSG LSGVVKNPIQ DIKITSDTNV PVNAGIRNNS
360 370 380 390 400
PRLSMQPFPH EFAQVRNAVF LHQNIYINGP KGCGKSNLVH SLFDYYSLNS
410 420 430 440 450
IYFQMIVSCS EIDRSSFAKF QSFWNNVFIQ AERYEPSIIY LDDVHCLISS
460 470 480 490 500
SNENGELGFV EEREIAFLQH QIINLKRKRK IIFIGFGEEF LTFSENLVLP
510 520 530 540 550
LLFQIKIALP SLAVTRRKEI LTTIFQENFS DITMDSIEFI SVKTEGYLMT
560 570 580 590 600
DLVLFVKRLL SEAFVEKIQN GPKHLMNKGL IEKTLKDFVP LQLRKAKFVK
610 620 630 640 650
SSIRWIDIAG MQEAKEAVRD IIESPVKYSL IYKQCRLRLP TGILLFGYPG
660 670 680 690 700
CGKTYLASAI SSTFPVQFIS IKGPELLDKY IGKSEQGVRD LFSRAQMAKP
710 720 730 740 750
CVLFFDEFDS VAPRRGQDST GVTDRVVNQI LTQMDGAESL DGVYIVAATT
760 770 780 790 800
RPDMIDPALL RPGRLDKLIF CDLPNEEERL EVLQKLANRF HIENAAMLKK
810 820 830 840 850
LSTLTDGYTY ADLSSLLYDA HLIAVHKLLK RVSINAVDPS QTTSSFTNLT
860 870 880 890 900
TESKRNASML ALPPESRYNQ NMQSMSDSKS VVIEDYMLME ALKKNSPSLN
910 920 930
SEEFEHLSNL YRDFRSKLFE PELNARNTDV GSKTRQI
Length:937
Mass (Da):105,905
Last modified:November 1, 1998 - v1
Checksum:iCF4550406886543F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329672 Genomic DNA. Translation: CAA19256.1.
PIRiT41400.
RefSeqiNP_587770.1. NM_001022763.2.

Genome annotation databases

EnsemblFungiiSPCC553.03.1; SPCC553.03.1:pep; SPCC553.03.
GeneIDi2539405.
KEGGispo:SPCC553.03.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329672 Genomic DNA. Translation: CAA19256.1.
PIRiT41400.
RefSeqiNP_587770.1. NM_001022763.2.

3D structure databases

ProteinModelPortaliO74941.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi275970. 16 interactions.
MINTiMINT-4681950.

Proteomic databases

MaxQBiO74941.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPCC553.03.1; SPCC553.03.1:pep; SPCC553.03.
GeneIDi2539405.
KEGGispo:SPCC553.03.

Organism-specific databases

EuPathDBiFungiDB:SPCC553.03.
PomBaseiSPCC553.03. pex1.

Phylogenomic databases

InParanoidiO74941.
OrthoDBiEOG092C0WJM.
PhylomeDBiO74941.

Miscellaneous databases

PROiO74941.

Family and domain databases

Gene3Di3.10.330.10. 1 hit.
3.40.50.300. 2 hits.
InterProiIPR003593. AAA+_ATPase.
IPR003959. ATPase_AAA_core.
IPR029067. CDC48_domain_2-like.
IPR027417. P-loop_NTPase.
IPR015342. PEX-N_psi_beta-barrel.
IPR025653. Pex1.
[Graphical view]
PANTHERiPTHR23077:SF12. PTHR23077:SF12. 3 hits.
PfamiPF00004. AAA. 2 hits.
PF09262. PEX-1N. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 2 hits.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 3 hits.
SSF54585. SSF54585. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiPEX1_SCHPO
AccessioniPrimary (citable) accession number: O74941
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 5, 2009
Last sequence update: November 1, 1998
Last modified: September 7, 2016
This is version 97 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.