Reviewed,
UniProtKB/Swiss-Prot O74935 (ACOX2_YARLI)
Last modified
June 16, 2009.
Version 55.
History...
Clusters with 100%,
90%,
50% identity |
Documents (2) |
Third-party data |
Customize display | text xml rdf/xml gff fasta |
Names and origin
| Protein names | Recommended name: Acyl-coenzyme A oxidase 2 Short name=Acyl-CoA oxidase 2 EC=1.3.3.6 | ||||||
| Gene names |
| ||||||
| Organism | Yarrowia lipolytica (Candida lipolytica) [Complete proteome] | ||||||
| Taxonomic identifier | 4952 [NCBI] | ||||||
| Taxonomic lineage | Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Dipodascaceae › Yarrowia |
Protein attributes
| Sequence length | 700 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Evidence at protein level. |
General annotation (Comments)
| Function | Oxidizes strain chain acyl-CoAs with a chain length of 10 to 14 carbons. Also active toward the 2S isomers of acyl-CoA-esters containing a 2-methyl group. |
| Catalytic activity | Acyl-CoA + O2 = trans-2,3-dehydroacyl-CoA + H2O2. |
| Cofactor | FAD. |
| Pathway | |
| Subunit structure | Heteropentamer composed of five different subunits. Ref.3 |
| Subcellular location | |
| Sequence similarities | Belongs to the acyl-CoA oxidase family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Fatty acid metabolism Lipid metabolism |
| Cellular component | Peroxisome |
| Ligand | FAD Flavoprotein |
| Molecular function | Oxidoreductase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | fatty acid beta-oxidation Inferred from electronic annotation. Source: InterPro oxidation reductionInferred from electronic annotation. Source: UniProtKB-KW |
| Cellular component | peroxisome Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | FAD binding Inferred from electronic annotation. Source: InterPro acyl-CoA dehydrogenase activityInferred from electronic annotation. Source: InterPro acyl-CoA oxidase activityInferred from electronic annotation. Source: EC electron carrier activityInferred from electronic annotation. Source: InterPro |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||
Molecule processing | |||||||
|---|---|---|---|---|---|---|---|
| Chain | 1 – 700 | 700 | Acyl-coenzyme A oxidase 2 | PRO_0000204702 | |||
Sequences
| ||||||||||||||||||
References
Cross-references
Sequence databases | |
|---|---|
| AJ001300 Genomic DNA. Translation: CAA04660.1. CR382132 Genomic DNA. Translation: CAG78071.1. | |
| RefSeq | XP_505264.1. |
3D structure databases | |
| HSSP | HSSP built from PDB template 1IS2 based on UniProtKB P07872. |
| ModBase | Search... |
Genome annotation databases | |
| GeneID | 2907872. |
| KEGG | yli:YALI0F10857g. |
Phylogenomic databases | |
| HOGENOM | O74935. |
| OMA | O74935. ANASERT. |
Enzyme and pathway databases | |
| BRENDA | 1.3.3.6. 3602. |
Family and domain databases | |
| InterPro | IPR006090. Acyl-CoA_Oxase/DH_1. IPR006091. Acyl-CoA_Oxase/DH_M. IPR012258. Acyl-CoA_oxidase. IPR002655. Acyl-CoA_oxidase_C. IPR013786. AcylCoA_DH/ox_N. IPR013764. AcylCoA_oxidase/DH_1/2_C. [Graphical view] |
| Gene3D | G3DSA:2.40.110.10. Acyl_CoA_DH/ox_M. 1 hit. G3DSA:1.10.540.10. AcylCoA_DH/ox_N. 1 hit. G3DSA:1.20.140.10. AcylCoA_DH_1/2_C. 2 hits. |
| PANTHER | PTHR10909:SF11. Acyl-CoA_oxidase. 1 hit. |
| Pfam | PF01756. ACOX. 1 hit. PF00441. Acyl-CoA_dh_1. 1 hit. PF02770. Acyl-CoA_dh_M. 1 hit. [Graphical view] |
| PIRSF | PIRSF000168. Acyl-CoA_oxidase. 1 hit. |
| ProtoNet | Search... |
Entry information
| Entry name | ACOX2_YARLI | ||||||||
| Accession | Primary (citable) accession number: O74935 Secondary accession number(s): Q6C248 | ||||||||
| Entry history |
| ||||||||
| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | FPAP (Fungal Proteome Annotation Project) | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

Clusters with


