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O74932

- TPS1_YARLI

UniProt

O74932 - TPS1_YARLI

Protein

Alpha,alpha-trehalose-phosphate synthase [UDP-forming]

Gene

TPS1

Organism
Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 67 (01 Oct 2014)
      Sequence version 1 (01 Nov 1998)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    UDP-glucose + D-glucose 6-phosphate = UDP + alpha,alpha-trehalose 6-phosphate.

    GO - Molecular functioni

    1. alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity Source: UniProtKB-EC

    GO - Biological processi

    1. trehalose biosynthetic process Source: InterPro

    Keywords - Molecular functioni

    Glycosyltransferase, Transferase

    Protein family/group databases

    CAZyiGT20. Glycosyltransferase Family 20.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Alpha,alpha-trehalose-phosphate synthase [UDP-forming] (EC:2.4.1.15)
    Alternative name(s):
    Trehalose-6-phosphate synthase
    UDP-glucose-glucosephosphate glucosyltransferase
    Gene namesi
    Name:TPS1
    Ordered Locus Names:YALI0E14685g
    OrganismiYarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica)
    Taxonomic identifieri284591 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDipodascaceaeYarrowia
    ProteomesiUP000001300: Chromosome E

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 469469Alpha,alpha-trehalose-phosphate synthase [UDP-forming]PRO_0000122501Add
    BLAST

    Proteomic databases

    PRIDEiO74932.

    Interactioni

    Protein-protein interaction databases

    STRINGi4952.O74932.

    Structurei

    3D structure databases

    ProteinModelPortaliO74932.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the glycosyltransferase 20 family.Curated

    Phylogenomic databases

    eggNOGiCOG0380.
    HOGENOMiHOG000191477.
    KOiK00697.
    OMAiWLAYREA.
    OrthoDBiEOG76QFS6.

    Family and domain databases

    InterProiIPR001830. Glyco_trans_20.
    IPR012766. Trehalose_OtsA.
    [Graphical view]
    PfamiPF00982. Glyco_transf_20. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR02400. trehalose_OtsA. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    O74932-1 [UniParc]FASTAAdd to Basket

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    MPNVLVISNR LPVTISREED GTYKYTMSSG GLVTALSGLK QSTTFQWFGW    50
    PGLEIPEKDK PRLINDLETM FSCVPVFMDD DLADLHYNGF SNSILWPLFH 100
    YHPGEMNFDQ VAWEAYTQAN RLFAKKVASI VKPGDIVWVH DYHLMLLPEM 150
    LREECENNSA LDGLKIGFFL HTPFPSSEIY RILPVRKEVL TGVLSCNLIG 200
    FHTYDYARHF LSSVSRILDL ETMPNGTYYK GRHVVVGAFP IGIDVNKFLE 250
    GCKRPAVQER IAQLQDKFKG IKVVVGVDRL DYIKGVPQKL HAFEVFLSEH 300
    PEWIGKVVLV QVAVPSRGLV EEYQNLRAVV NELVGRINGM FGTVEFTPIH 350
    FMHRSVDFNE LIALYSISDV CFVSSTRDGM NLVSYEYVAC QTEKHGSLIL 400
    SEFTGAAQSL NGALIVNPWN TEDMAEALYD SLTFSPEKKA ENHRKLFKYV 450
    SKYTSQHWGE AFVSELKRC 469
    Length:469
    Mass (Da):53,259
    Last modified:November 1, 1998 - v1
    Checksum:iBCA5A82B98B0F23E
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AJ011032 mRNA. Translation: CAA09463.1.
    CR382131 Genomic DNA. Translation: CAG79544.1.
    RefSeqiXP_503951.1. XM_503951.1.

    Genome annotation databases

    EnsemblFungiiCAG79544; CAG79544; YALI0_E14685g.
    GeneIDi2912305.
    KEGGiyli:YALI0E14685g.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AJ011032 mRNA. Translation: CAA09463.1 .
    CR382131 Genomic DNA. Translation: CAG79544.1 .
    RefSeqi XP_503951.1. XM_503951.1.

    3D structure databases

    ProteinModelPortali O74932.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 4952.O74932.

    Protein family/group databases

    CAZyi GT20. Glycosyltransferase Family 20.

    Proteomic databases

    PRIDEi O74932.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii CAG79544 ; CAG79544 ; YALI0_E14685g .
    GeneIDi 2912305.
    KEGGi yli:YALI0E14685g.

    Phylogenomic databases

    eggNOGi COG0380.
    HOGENOMi HOG000191477.
    KOi K00697.
    OMAi WLAYREA.
    OrthoDBi EOG76QFS6.

    Family and domain databases

    InterProi IPR001830. Glyco_trans_20.
    IPR012766. Trehalose_OtsA.
    [Graphical view ]
    Pfami PF00982. Glyco_transf_20. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR02400. trehalose_OtsA. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Molecular cloning of the TPS1 gene from Yarrowia lipolytica."
      Petit T., Flores C.L., Gancedo C.
      Submitted (SEP-1998) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].
      Strain: PO1a.
    2. "Genome evolution in yeasts."
      Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I., de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L., Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.
      , Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J., Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E., Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C., Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M., Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S., Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F., Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M., Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M., Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C., Weissenbach J., Wincker P., Souciet J.-L.
      Nature 430:35-44(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: CLIB 122 / E 150.

    Entry informationi

    Entry nameiTPS1_YARLI
    AccessioniPrimary (citable) accession number: O74932
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: June 6, 2002
    Last sequence update: November 1, 1998
    Last modified: October 1, 2014
    This is version 67 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3