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Protein

Alpha,alpha-trehalose-phosphate synthase [UDP-forming]

Gene

TPS1

Organism
Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Catalytic activityi

UDP-alpha-D-glucose + D-glucose 6-phosphate = UDP + alpha,alpha-trehalose 6-phosphate.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosyltransferase, Transferase

Protein family/group databases

CAZyiGT20 Glycosyltransferase Family 20

Names & Taxonomyi

Protein namesi
Recommended name:
Alpha,alpha-trehalose-phosphate synthase [UDP-forming] (EC:2.4.1.15)
Alternative name(s):
Trehalose-6-phosphate synthase
UDP-glucose-glucosephosphate glucosyltransferase
Gene namesi
Name:TPS1
Ordered Locus Names:YALI0E14685g
OrganismiYarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica)
Taxonomic identifieri284591 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDipodascaceaeYarrowia
Proteomesi
  • UP000001300 Componenti: Chromosome E

Subcellular locationi

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001225011 – 469Alpha,alpha-trehalose-phosphate synthase [UDP-forming]Add BLAST469

Proteomic databases

PRIDEiO74932

Interactioni

Protein-protein interaction databases

STRINGi4952.XP_503951.1

Structurei

3D structure databases

ProteinModelPortaliO74932
SMRiO74932
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyltransferase 20 family.Curated

Phylogenomic databases

HOGENOMiHOG000191477
InParanoidiO74932
KOiK00697
OMAiIEFMPIH
OrthoDBiEOG092C0LDC

Family and domain databases

CDDicd03788 GT1_TPS, 1 hit
InterProiView protein in InterPro
IPR001830 Glyco_trans_20
IPR012766 Trehalose_OtsA
PfamiView protein in Pfam
PF00982 Glyco_transf_20, 1 hit
TIGRFAMsiTIGR02400 trehalose_OtsA, 1 hit

Sequencei

Sequence statusi: Complete.

O74932-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPNVLVISNR LPVTISREED GTYKYTMSSG GLVTALSGLK QSTTFQWFGW
60 70 80 90 100
PGLEIPEKDK PRLINDLETM FSCVPVFMDD DLADLHYNGF SNSILWPLFH
110 120 130 140 150
YHPGEMNFDQ VAWEAYTQAN RLFAKKVASI VKPGDIVWVH DYHLMLLPEM
160 170 180 190 200
LREECENNSA LDGLKIGFFL HTPFPSSEIY RILPVRKEVL TGVLSCNLIG
210 220 230 240 250
FHTYDYARHF LSSVSRILDL ETMPNGTYYK GRHVVVGAFP IGIDVNKFLE
260 270 280 290 300
GCKRPAVQER IAQLQDKFKG IKVVVGVDRL DYIKGVPQKL HAFEVFLSEH
310 320 330 340 350
PEWIGKVVLV QVAVPSRGLV EEYQNLRAVV NELVGRINGM FGTVEFTPIH
360 370 380 390 400
FMHRSVDFNE LIALYSISDV CFVSSTRDGM NLVSYEYVAC QTEKHGSLIL
410 420 430 440 450
SEFTGAAQSL NGALIVNPWN TEDMAEALYD SLTFSPEKKA ENHRKLFKYV
460
SKYTSQHWGE AFVSELKRC
Length:469
Mass (Da):53,259
Last modified:November 1, 1998 - v1
Checksum:iBCA5A82B98B0F23E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ011032 mRNA Translation: CAA09463.1
CR382131 Genomic DNA Translation: CAG79544.1
RefSeqiXP_503951.1, XM_503951.1

Genome annotation databases

EnsemblFungiiCAG79544; CAG79544; YALI0_E14685g
GeneIDi2912305
KEGGiyli:YALI0E14685g

Similar proteinsi

Entry informationi

Entry nameiTPS1_YARLI
AccessioniPrimary (citable) accession number: O74932
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 6, 2002
Last sequence update: November 1, 1998
Last modified: April 25, 2018
This is version 85 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health