ID RL24B_SCHPO Reviewed; 149 AA. AC O74884; DT 27-SEP-2004, integrated into UniProtKB/Swiss-Prot. DT 01-NOV-1998, sequence version 1. DT 27-MAR-2024, entry version 133. DE RecName: Full=Large ribosomal subunit protein eL24B {ECO:0000305}; DE AltName: Full=60S ribosomal protein L24-B; GN Name=rpl2402; Synonyms=rpl24, rpl24b; ORFNames=SPCC330.14c; OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast). OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; OC Schizosaccharomyces. OX NCBI_TaxID=284812; RN [1] RP NUCLEOTIDE SEQUENCE [MRNA]. RA Kawamukai M.; RT "S.pombe ribosomal protein L24 homolog."; RL Submitted (SEP-1999) to the EMBL/GenBank/DDBJ databases. RN [2] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=972 / ATCC 24843; RX PubMed=11859360; DOI=10.1038/nature724; RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M., RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., RA Nurse P.; RT "The genome sequence of Schizosaccharomyces pombe."; RL Nature 415:871-880(2002). RN [3] RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS]. RX PubMed=16823372; DOI=10.1038/nbt1222; RA Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S., RA Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S., RA Yoshida M.; RT "ORFeome cloning and global analysis of protein localization in the fission RT yeast Schizosaccharomyces pombe."; RL Nat. Biotechnol. 24:841-847(2006). RN [4] RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-50, AND IDENTIFICATION BY RP MASS SPECTROMETRY. RX PubMed=18257517; DOI=10.1021/pr7006335; RA Wilson-Grady J.T., Villen J., Gygi S.P.; RT "Phosphoproteome analysis of fission yeast."; RL J. Proteome Res. 7:1088-1097(2008). CC -!- FUNCTION: Component of the ribosome, a large ribonucleoprotein complex CC responsible for the synthesis of proteins in the cell. The small CC ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the CC encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) CC molecules. The large subunit (LSU) contains the ribosomal catalytic CC site termed the peptidyl transferase center (PTC), which catalyzes the CC formation of peptide bonds, thereby polymerizing the amino acids CC delivered by tRNAs into a polypeptide chain. The nascent polypeptides CC leave the ribosome through a tunnel in the LSU and interact with CC protein factors that function in enzymatic processing, targeting, and CC the membrane insertion of nascent chains at the exit of the ribosomal CC tunnel. {ECO:0000250|UniProtKB:P24000}. CC -!- SUBUNIT: Component of the small ribosomal subunit (SSU). Mature yeast CC ribosomes consist of a small (40S) and a large (60S) subunit. The 40S CC small subunit contains 1 molecule of ribosomal RNA (18S rRNA) and at CC least 33 different proteins. The large 60S subunit contains 3 rRNA CC molecules (25S, 5.8S and 5S rRNA) and at least 46 different proteins. CC {ECO:0000250|UniProtKB:P24000}. CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:16823372}. CC -!- MISCELLANEOUS: There are 2 genes for eL24 in S.pombe. CC -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eL24 family. CC {ECO:0000305}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AB032714; BAA84653.1; -; mRNA. DR EMBL; CU329672; CAA20919.1; -; Genomic_DNA. DR PIR; T41324; T41324. DR RefSeq; NP_587714.1; NM_001022709.2. DR AlphaFoldDB; O74884; -. DR SMR; O74884; -. DR BioGRID; 275430; 23. DR IntAct; O74884; 2. DR STRING; 284812.O74884; -. DR iPTMnet; O74884; -. DR MaxQB; O74884; -. DR PaxDb; 4896-SPCC330-14c-1; -. DR EnsemblFungi; SPCC330.14c.1; SPCC330.14c.1:pep; SPCC330.14c. DR GeneID; 2538849; -. DR KEGG; spo:SPCC330.14c; -. DR PomBase; SPCC330.14c; rpl2402. DR VEuPathDB; FungiDB:SPCC330.14c; -. DR eggNOG; KOG1722; Eukaryota. DR HOGENOM; CLU_106411_0_0_1; -. DR InParanoid; O74884; -. DR OMA; IAWTQVF; -. DR PhylomeDB; O74884; -. DR PRO; PR:O74884; -. DR Proteomes; UP000002485; Chromosome III. DR GO; GO:0005829; C:cytosol; HDA:PomBase. DR GO; GO:0022625; C:cytosolic large ribosomal subunit; IBA:GO_Central. DR GO; GO:0003729; F:mRNA binding; IBA:GO_Central. DR GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central. DR GO; GO:0002181; P:cytoplasmic translation; IBA:GO_Central. DR CDD; cd00472; Ribosomal_L24e_L24; 1. DR Gene3D; 6.10.250.1270; -; 1. DR Gene3D; 2.30.170.20; Ribosomal protein L24e; 1. DR InterPro; IPR038630; L24e/L24_sf. DR InterPro; IPR000988; Ribosomal_eL24-rel. DR InterPro; IPR023442; Ribosomal_eL24_CS. DR PANTHER; PTHR10792; 60S RIBOSOMAL PROTEIN L24; 1. DR PANTHER; PTHR10792:SF1; TRASH DOMAIN-CONTAINING PROTEIN; 1. DR Pfam; PF01246; Ribosomal_L24e; 1. DR SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 1. DR PROSITE; PS01073; RIBOSOMAL_L24E; 1. PE 1: Evidence at protein level; KW Cytoplasm; Phosphoprotein; Reference proteome; Ribonucleoprotein; KW Ribosomal protein. FT CHAIN 1..149 FT /note="Large ribosomal subunit protein eL24B" FT /id="PRO_0000136892" FT REGION 96..149 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 96..129 FT /note="Basic and acidic residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT MOD_RES 50 FT /note="Phosphoserine" FT /evidence="ECO:0000269|PubMed:18257517" SQ SEQUENCE 149 AA; 16912 MW; E34171D4344C8193 CRC64; MKVEVCSFSG SKVYPGAGRL FVRGDNKVFR FVNKKSESLF LQRKNPRRLS WTVLYRRMHK KGISEEHAKK RTRRTVKHQR GIVGANLDVI KEKRNQRPEV RAAARAAALK QRKDKRAASE SEKKAIKAKS AASSARGQAI KNAKVAARR //