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Protein

Meiotically up-regulated gene 73 protein

Gene

mug73

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Has a role in meiosis.1 Publication

GO - Molecular functioni

  1. ion channel activity Source: InterPro

GO - Biological processi

  1. meiotic cell cycle Source: UniProtKB-KW
  2. regulation of ion transmembrane transport Source: PomBase
Complete GO annotation...

Keywords - Biological processi

Meiosis

Names & Taxonomyi

Protein namesi
Recommended name:
Meiotically up-regulated gene 73 protein
Gene namesi
Name:mug73
ORF Names:SPCC31H12.02c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
ProteomesiUP000002485: Chromosome III

Organism-specific databases

PomBaseiSPCC31H12.02c.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei28 – 4821HelicalSequence AnalysisAdd
BLAST
Transmembranei59 – 7921HelicalSequence AnalysisAdd
BLAST
Transmembranei103 – 12321HelicalSequence AnalysisAdd
BLAST
Transmembranei125 – 14521HelicalSequence AnalysisAdd
BLAST
Transmembranei154 – 17421HelicalSequence AnalysisAdd
BLAST
Transmembranei190 – 21021HelicalSequence AnalysisAdd
BLAST
Transmembranei224 – 24421HelicalSequence AnalysisAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: PomBase
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 306306Meiotically up-regulated gene 73 proteinPRO_0000278563Add
BLAST

Interactioni

Protein-protein interaction databases

BioGridi275314. 38 interactions.
MINTiMINT-4681462.
STRINGi4896.SPCC31H12.02c-1.

Structurei

3D structure databases

ProteinModelPortaliO74870.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG5524.
InParanoidiO74870.
OMAiCEGGNLI.
OrthoDBiEOG754J0K.
PhylomeDBiO74870.

Family and domain databases

InterProiIPR001425. Arc/bac/fun_rhod.
IPR029730. Arc/bac/fun_rhod-like.
[Graphical view]
PfamiPF01036. Bac_rhodopsin. 1 hit.
[Graphical view]
PRINTSiPR00251. BACTRLOPSIN.
SMARTiSM01021. Bac_rhodopsin. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O74870-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNAKLSSSGM VLKELPEVAL QKISSNYYWA VFAVFLLCAI VFPLVSIFSL
60 70 80 90 100
PQKQTYHRFF SILSLVSCLA YFTMACNYGL KNVFSSASFF REVSVRMVYY
110 120 130 140 150
VRYIQWLINF PLIIVMLHWT VGVSILEIAY VVCYVLFAIV CLLAAALTSS
160 170 180 190 200
PYKWAYYGFS FVGYFIALAH SVVLHKKYAS RLETSARLGF LWSIVYLHVI
210 220 230 240 250
WFLYYACWIL SEGLNVISPI GEAIFYSILD LFEFGFFGAA FSWMLDLVGI
260 270 280 290 300
ENFKSPQSIP LGACSPADDK FSMCPDMEAQ NQADDLAVET RIQISNLPSS

PTKNNC
Length:306
Mass (Da):34,664
Last modified:November 1, 1998 - v1
Checksum:i5C18E637628DF080
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329672 Genomic DNA. Translation: CAA21219.1.
PIRiT41290.
RefSeqiNP_587895.1. NM_001022887.2.

Genome annotation databases

EnsemblFungiiSPCC31H12.02c.1; SPCC31H12.02c.1:pep; SPCC31H12.02c.
GeneIDi2538730.
KEGGispo:SPCC31H12.02c.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329672 Genomic DNA. Translation: CAA21219.1.
PIRiT41290.
RefSeqiNP_587895.1. NM_001022887.2.

3D structure databases

ProteinModelPortaliO74870.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi275314. 38 interactions.
MINTiMINT-4681462.
STRINGi4896.SPCC31H12.02c-1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPCC31H12.02c.1; SPCC31H12.02c.1:pep; SPCC31H12.02c.
GeneIDi2538730.
KEGGispo:SPCC31H12.02c.

Organism-specific databases

PomBaseiSPCC31H12.02c.

Phylogenomic databases

eggNOGiCOG5524.
InParanoidiO74870.
OMAiCEGGNLI.
OrthoDBiEOG754J0K.
PhylomeDBiO74870.

Miscellaneous databases

NextBioi20799915.

Family and domain databases

InterProiIPR001425. Arc/bac/fun_rhod.
IPR029730. Arc/bac/fun_rhod-like.
[Graphical view]
PfamiPF01036. Bac_rhodopsin. 1 hit.
[Graphical view]
PRINTSiPR00251. BACTRLOPSIN.
SMARTiSM01021. Bac_rhodopsin. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The genome sequence of Schizosaccharomyces pombe."
    Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.
    , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
    Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 972 / ATCC 24843.
  2. "A large-scale screen in S. pombe identifies seven novel genes required for critical meiotic events."
    Martin-Castellanos C., Blanco M., Rozalen A.E., Perez-Hidalgo L., Garcia A.I., Conde F., Mata J., Ellermeier C., Davis L., San-Segundo P., Smith G.R., Moreno S.
    Curr. Biol. 15:2056-2062(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION IN MEIOSIS.

Entry informationi

Entry nameiMUG73_SCHPO
AccessioniPrimary (citable) accession number: O74870
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 20, 2007
Last sequence update: November 1, 1998
Last modified: January 7, 2015
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. 7-transmembrane G-linked receptors
    List of 7-transmembrane G-linked receptor entries
  2. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.