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O74870 (MUG73_SCHPO) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 72. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Meiotically up-regulated gene 73 protein
Gene names
Name:mug73
ORF Names:SPCC31H12.02c
OrganismSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) [Reference proteome]
Taxonomic identifier284812 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces

Protein attributes

Sequence length306 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Has a role in meiosis. Ref.2

Subcellular location

Membrane; Multi-pass membrane protein Potential.

Sequence similarities

Belongs to the archaeal/bacterial/fungal opsin family.

Ontologies

Keywords
   Biological processMeiosis
   Cellular componentMembrane
   DomainTransmembrane
Transmembrane helix
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processmeiotic nuclear division

Inferred from electronic annotation. Source: UniProtKB-KW

transmembrane transport

Inferred from sequence model. Source: PomBase

   Cellular_componentintegral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionion channel activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 306306Meiotically up-regulated gene 73 protein
PRO_0000278563

Regions

Transmembrane28 – 4821Helical; Potential
Transmembrane59 – 7921Helical; Potential
Transmembrane103 – 12321Helical; Potential
Transmembrane125 – 14521Helical; Potential
Transmembrane154 – 17421Helical; Potential
Transmembrane190 – 21021Helical; Potential
Transmembrane224 – 24421Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
O74870 [UniParc].

Last modified November 1, 1998. Version 1.
Checksum: 5C18E637628DF080

FASTA30634,664
        10         20         30         40         50         60 
MNAKLSSSGM VLKELPEVAL QKISSNYYWA VFAVFLLCAI VFPLVSIFSL PQKQTYHRFF 

        70         80         90        100        110        120 
SILSLVSCLA YFTMACNYGL KNVFSSASFF REVSVRMVYY VRYIQWLINF PLIIVMLHWT 

       130        140        150        160        170        180 
VGVSILEIAY VVCYVLFAIV CLLAAALTSS PYKWAYYGFS FVGYFIALAH SVVLHKKYAS 

       190        200        210        220        230        240 
RLETSARLGF LWSIVYLHVI WFLYYACWIL SEGLNVISPI GEAIFYSILD LFEFGFFGAA 

       250        260        270        280        290        300 
FSWMLDLVGI ENFKSPQSIP LGACSPADDK FSMCPDMEAQ NQADDLAVET RIQISNLPSS 


PTKNNC 

« Hide

References

« Hide 'large scale' references
[1]"The genome sequence of Schizosaccharomyces pombe."
Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M. expand/collapse author list , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 972 / ATCC 24843.
[2]"A large-scale screen in S. pombe identifies seven novel genes required for critical meiotic events."
Martin-Castellanos C., Blanco M., Rozalen A.E., Perez-Hidalgo L., Garcia A.I., Conde F., Mata J., Ellermeier C., Davis L., San-Segundo P., Smith G.R., Moreno S.
Curr. Biol. 15:2056-2062(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: FUNCTION IN MEIOSIS.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CU329672 Genomic DNA. Translation: CAA21219.1.
PIRT41290.
RefSeqNP_587895.1. NM_001022887.2.

3D structure databases

ProteinModelPortalO74870.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid275314. 38 interactions.
MINTMINT-4681462.
STRING4896.SPCC31H12.02c-1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiSPCC31H12.02c.1; SPCC31H12.02c.1:pep; SPCC31H12.02c.
GeneID2538730.
KEGGspo:SPCC31H12.02c.

Organism-specific databases

PomBaseSPCC31H12.02c.

Phylogenomic databases

eggNOGCOG5524.
OMACEGGNLI.
OrthoDBEOG754J0K.
PhylomeDBO74870.

Family and domain databases

Gene3D1.20.1070.10. 1 hit.
InterProIPR017452. GPCR_Rhodpsn_7TM.
IPR001425. Rhodopsin_arc/bac/fun.
[Graphical view]
PfamPF01036. Bac_rhodopsin. 1 hit.
[Graphical view]
PRINTSPR00251. BACTRLOPSIN.
SMARTSM01021. Bac_rhodopsin. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio20799915.

Entry information

Entry nameMUG73_SCHPO
AccessionPrimary (citable) accession number: O74870
Entry history
Integrated into UniProtKB/Swiss-Prot: February 20, 2007
Last sequence update: November 1, 1998
Last modified: April 16, 2014
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Schizosaccharomyces pombe

Schizosaccharomyces pombe: entries and gene names

7-transmembrane G-linked receptors

List of 7-transmembrane G-linked receptor entries