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O74870

- MUG73_SCHPO

UniProt

O74870 - MUG73_SCHPO

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Protein
Meiotically up-regulated gene 73 protein
Gene
mug73, SPCC31H12.02c
Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Functioni

Has a role in meiosis.1 Publication

GO - Molecular functioni

  1. ion channel activity Source: InterPro
Complete GO annotation...

GO - Biological processi

  1. meiotic nuclear division Source: UniProtKB-KW
  2. transmembrane transport Source: PomBase
Complete GO annotation...

Keywords - Biological processi

Meiosis

Names & Taxonomyi

Protein namesi
Recommended name:
Meiotically up-regulated gene 73 protein
Gene namesi
Name:mug73
ORF Names:SPCC31H12.02c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
ProteomesiUP000002485: Chromosome III

Organism-specific databases

PomBaseiSPCC31H12.02c.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei28 – 4821Helical; Reviewed prediction
Add
BLAST
Transmembranei59 – 7921Helical; Reviewed prediction
Add
BLAST
Transmembranei103 – 12321Helical; Reviewed prediction
Add
BLAST
Transmembranei125 – 14521Helical; Reviewed prediction
Add
BLAST
Transmembranei154 – 17421Helical; Reviewed prediction
Add
BLAST
Transmembranei190 – 21021Helical; Reviewed prediction
Add
BLAST
Transmembranei224 – 24421Helical; Reviewed prediction
Add
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 306306Meiotically up-regulated gene 73 protein
PRO_0000278563Add
BLAST

Interactioni

Protein-protein interaction databases

BioGridi275314. 38 interactions.
MINTiMINT-4681462.
STRINGi4896.SPCC31H12.02c-1.

Structurei

3D structure databases

ProteinModelPortaliO74870.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG5524.
OMAiCEGGNLI.
OrthoDBiEOG754J0K.
PhylomeDBiO74870.

Family and domain databases

Gene3Di1.20.1070.10. 1 hit.
InterProiIPR001425. Arc/bac/fun_rhod.
IPR017452. GPCR_Rhodpsn_7TM.
[Graphical view]
PRINTSiPR00251. BACTRLOPSIN.

Sequencei

Sequence statusi: Complete.

O74870-1 [UniParc]FASTAAdd to Basket

« Hide

MNAKLSSSGM VLKELPEVAL QKISSNYYWA VFAVFLLCAI VFPLVSIFSL    50
PQKQTYHRFF SILSLVSCLA YFTMACNYGL KNVFSSASFF REVSVRMVYY 100
VRYIQWLINF PLIIVMLHWT VGVSILEIAY VVCYVLFAIV CLLAAALTSS 150
PYKWAYYGFS FVGYFIALAH SVVLHKKYAS RLETSARLGF LWSIVYLHVI 200
WFLYYACWIL SEGLNVISPI GEAIFYSILD LFEFGFFGAA FSWMLDLVGI 250
ENFKSPQSIP LGACSPADDK FSMCPDMEAQ NQADDLAVET RIQISNLPSS 300
PTKNNC 306
Length:306
Mass (Da):34,664
Last modified:November 1, 1998 - v1
Checksum:i5C18E637628DF080
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CU329672 Genomic DNA. Translation: CAA21219.1.
PIRiT41290.
RefSeqiNP_587895.1. NM_001022887.2.

Genome annotation databases

EnsemblFungiiSPCC31H12.02c.1; SPCC31H12.02c.1:pep; SPCC31H12.02c.
GeneIDi2538730.
KEGGispo:SPCC31H12.02c.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CU329672 Genomic DNA. Translation: CAA21219.1 .
PIRi T41290.
RefSeqi NP_587895.1. NM_001022887.2.

3D structure databases

ProteinModelPortali O74870.
ModBasei Search...

Protein-protein interaction databases

BioGridi 275314. 38 interactions.
MINTi MINT-4681462.
STRINGi 4896.SPCC31H12.02c-1.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii SPCC31H12.02c.1 ; SPCC31H12.02c.1:pep ; SPCC31H12.02c .
GeneIDi 2538730.
KEGGi spo:SPCC31H12.02c.

Organism-specific databases

PomBasei SPCC31H12.02c.

Phylogenomic databases

eggNOGi COG5524.
OMAi CEGGNLI.
OrthoDBi EOG754J0K.
PhylomeDBi O74870.

Miscellaneous databases

NextBioi 20799915.

Family and domain databases

Gene3Di 1.20.1070.10. 1 hit.
InterProi IPR001425. Arc/bac/fun_rhod.
IPR017452. GPCR_Rhodpsn_7TM.
[Graphical view ]
PRINTSi PR00251. BACTRLOPSIN.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The genome sequence of Schizosaccharomyces pombe."
    Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.
    , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
    Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 972 / ATCC 24843.
  2. "A large-scale screen in S. pombe identifies seven novel genes required for critical meiotic events."
    Martin-Castellanos C., Blanco M., Rozalen A.E., Perez-Hidalgo L., Garcia A.I., Conde F., Mata J., Ellermeier C., Davis L., San-Segundo P., Smith G.R., Moreno S.
    Curr. Biol. 15:2056-2062(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION IN MEIOSIS.

Entry informationi

Entry nameiMUG73_SCHPO
AccessioniPrimary (citable) accession number: O74870
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 20, 2007
Last sequence update: November 1, 1998
Last modified: September 3, 2014
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. 7-transmembrane G-linked receptors
    List of 7-transmembrane G-linked receptor entries
  2. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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