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Protein

Probable FAD synthase

Gene

SPCC1235.04c

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Adenylates FMN to FAD.By similarity

Catalytic activityi

ATP + FMN = diphosphate + FAD.

Pathwayi: FAD biosynthesis

This protein is involved in step 1 of the subpathway that synthesizes FAD from FMN.
Proteins known to be involved in this subpathway in this organism are:
  1. Probable FAD synthase (SPCC1235.04c)
This subpathway is part of the pathway FAD biosynthesis, which is itself part of Cofactor biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes FAD from FMN, the pathway FAD biosynthesis and in Cofactor biosynthesis.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionNucleotidyltransferase, Transferase
LigandATP-binding, FAD, Flavoprotein, FMN, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-SPO-196843 Vitamin B2 (riboflavin) metabolism
UniPathwayiUPA00277; UER00407

Names & Taxonomyi

Protein namesi
Recommended name:
Probable FAD synthase (EC:2.7.7.2)
Alternative name(s):
FAD pyrophosphorylase
FMN adenylyltransferase
Flavin adenine dinucleotide synthase
Gene namesi
ORF Names:SPCC1235.04c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome III

Organism-specific databases

EuPathDBiFungiDB:SPCC1235.04c
PomBaseiSPCC1235.04c

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001006901 – 265Probable FAD synthaseAdd BLAST265

Proteomic databases

MaxQBiO74841
PaxDbiO74841
PRIDEiO74841

PTM databases

iPTMnetiO74841

Interactioni

Protein-protein interaction databases

STRINGi4896.SPCC1235.04c.1

Structurei

3D structure databases

ProteinModelPortaliO74841
SMRiO74841
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PAPS reductase family. FAD1 subfamily.Curated

Phylogenomic databases

HOGENOMiHOG000216561
InParanoidiO74841
KOiK00953
OMAiSIGNRSN
OrthoDBiEOG092C3NQ4
PhylomeDBiO74841

Family and domain databases

CDDicd01713 PAPS_reductase, 1 hit
Gene3Di3.40.50.620, 1 hit
InterProiView protein in InterPro
IPR002500 PAPS_reduct
IPR014729 Rossmann-like_a/b/a_fold
PfamiView protein in Pfam
PF01507 PAPS_reduct, 1 hit

Sequencei

Sequence statusi: Complete.

O74841-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDELERVYQS IKNIFTHSAP SEKLVGLQNR LSISLRFIEY AFETYQPERL
60 70 80 90 100
AMSFNGGKDC LVLFLLCIYY LKEKYKEQAQ AKLSNIPFVF VRPRDEFPEM
110 120 130 140 150
DDFVNECQSK YRLNIIKISL PMKEAFCKFL KEHKHIQAIL IGIRRLDPHG
160 170 180 190 200
LHRIAFEVTD KGWPKFMRIQ PILDWSYTEI WDLLLETNTK YCSLYDRGYT
210 220 230 240 250
SLGGVSDTSP NPALKNPDGT YSPAYLLSDG SLERAGRNNT VPFSRTNSRF
260
LYDSGASSYA SSEVS
Length:265
Mass (Da):30,608
Last modified:November 1, 1998 - v1
Checksum:iBC6C662E6F43A6F3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329672 Genomic DNA Translation: CAA21108.1
PIRiT40878
RefSeqiNP_587730.1, NM_001022725.2

Genome annotation databases

EnsemblFungiiSPCC1235.04c.1; SPCC1235.04c.1:pep; SPCC1235.04c
GeneIDi2539270
KEGGispo:SPCC1235.04c

Similar proteinsi

Entry informationi

Entry nameiFAD1_SCHPO
AccessioniPrimary (citable) accession number: O74841
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: November 1, 1998
Last modified: March 28, 2018
This is version 104 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  3. SIMILARITY comments
    Index of protein domains and families
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