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Protein

rRNA biogenesis protein rrp5

Gene

rrp5

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Involved in the biogenesis of rRNA. Required for the formation of 18S and 5.8S rRNA (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein

Keywords - Biological processi

Ribosome biogenesis, rRNA processing

Enzyme and pathway databases

ReactomeiR-SPO-6791226. Major pathway of rRNA processing in the nucleolus and cytosol.

Names & Taxonomyi

Protein namesi
Recommended name:
rRNA biogenesis protein rrp5
Alternative name(s):
Ribosomal RNA-processing protein 5
U3 small nucleolar RNA-associated protein rrp5
Short name:
U3 snoRNA-associated protein rrp5
Gene namesi
Name:rrp5By similarity
ORF Names:SPCC1183.07
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome III

Organism-specific databases

EuPathDBiFungiDB:SPCC1183.07.
PomBaseiSPCC1183.07. rrp5.

Subcellular locationi

GO - Cellular componenti

  • nucleolus Source: PomBase
  • small-subunit processome Source: PomBase
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003146291 – 1690rRNA biogenesis protein rrp5Add BLAST1690

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei1391Phosphothreonine1 Publication1
Modified residuei1394Phosphoserine1 Publication1
Modified residuei1684Phosphoserine1 Publication1
Modified residuei1686Phosphoserine1 Publication1

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiO74835.
PRIDEiO74835.

PTM databases

iPTMnetiO74835.

Interactioni

Subunit structurei

Component of the ribosomal small subunit (SSU) processome.By similarity

Protein-protein interaction databases

BioGridi275475. 8 interactors.
IntActiO74835. 1 interactor.

Structurei

3D structure databases

ProteinModelPortaliO74835.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini109 – 209S1 motif 1PROSITE-ProRule annotationAdd BLAST101
Domaini226 – 289S1 motif 2PROSITE-ProRule annotationAdd BLAST64
Domaini306 – 376S1 motif 3PROSITE-ProRule annotationAdd BLAST71
Domaini398 – 473S1 motif 4PROSITE-ProRule annotationAdd BLAST76
Domaini490 – 559S1 motif 5PROSITE-ProRule annotationAdd BLAST70
Domaini579 – 648S1 motif 6PROSITE-ProRule annotationAdd BLAST70
Domaini666 – 739S1 motif 7PROSITE-ProRule annotationAdd BLAST74
Domaini761 – 830S1 motif 8PROSITE-ProRule annotationAdd BLAST70
Domaini866 – 942S1 motif 9PROSITE-ProRule annotationAdd BLAST77
Domaini973 – 1044S1 motif 10PROSITE-ProRule annotationAdd BLAST72
Domaini1053 – 1122S1 motif 11PROSITE-ProRule annotationAdd BLAST70
Domaini1147 – 1216S1 motif 12PROSITE-ProRule annotationAdd BLAST70
Domaini1236 – 1307S1 motif 13PROSITE-ProRule annotationAdd BLAST72
Repeati1420 – 1452HAT 1Sequence analysisAdd BLAST33
Repeati1526 – 1558HAT 2Sequence analysisAdd BLAST33
Repeati1596 – 1628HAT 3Sequence analysisAdd BLAST33

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi1361 – 1366Poly-GluSequence analysis6

Sequence similaritiesi

Contains 3 HAT repeats.Sequence analysis
Contains 13 S1 motif domains.PROSITE-ProRule annotation

Keywords - Domaini

Repeat

Phylogenomic databases

HOGENOMiHOG000167551.
InParanoidiO74835.
KOiK14792.
OMAiKEWKDSF.
OrthoDBiEOG092C03ZV.
PhylomeDBiO74835.

Family and domain databases

Gene3Di1.25.40.10. 1 hit.
InterProiIPR003107. HAT.
IPR012340. NA-bd_OB-fold.
IPR022967. S1_dom.
IPR003029. S1_domain.
IPR008847. Suf.
IPR011990. TPR-like_helical_dom.
[Graphical view]
PfamiPF00575. S1. 5 hits.
PF05843. Suf. 1 hit.
[Graphical view]
SMARTiSM00386. HAT. 6 hits.
SM00316. S1. 13 hits.
[Graphical view]
SUPFAMiSSF48452. SSF48452. 1 hit.
SSF50249. SSF50249. 12 hits.
PROSITEiPS50126. S1. 12 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O74835-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGNKRKRSN ASEGSDSQGN ERISSLSANE ATQDFPRGGA SSLTPLEYKE
60 70 80 90 100
AVLEAKKDFM ESASGTAELS KKTRPKKKGS KKSSKSELDN EENLKVHIQS
110 120 130 140 150
LRYKNITPGS LILGQIAQIN TLDLAVSLPN CLTGYVPITN ISDKLSDRLD
160 170 180 190 200
SIDNHAEDNA ATEEEDGLNQ IPDLMDLYKV GQWVRVSVTA LGSENTTKTG
210 220 230 240 250
KRHIELSLKP QDANGSAPEA ADFVAGSMIQ AVVSSIEDHG IVFDIGINNY
260 270 280 290 300
TGFLSKKHIN DFPFVEGQSL LCSVISKEDR IFHLSLTATS TKALEVMPSV
310 320 330 340 350
QAILPGDYIN VLVTDIKESG VIAKYMGVVD VTSDIYHSSP VKGEDLEDKF
360 370 380 390 400
QLAKSVPARV LFVIPGDPPK IAVSFLPHVL TFNFATPNTP HPDQLDIGFI
410 420 430 440 450
VNAAKVTYVS SSLGVFCDVG VPEISGFAHI SRLSDKKVAG ISPNSGPYKV
460 470 480 490 500
DSTHEARIIN YSYVDNLYIL SFQQSVLNQQ FLRIEDIEVG QFVDGTIAKL
510 520 530 540 550
IPQGIVVTIS EGINGLVPST HMADIALQFP ERRFKVGSSV KCRVLSTNVL
560 570 580 590 600
RKRVLLTLKK SLLNTDLPLI YDYEQATPGT QTVGTLARIF EDGAIVEFYN
610 620 630 640 650
SVRAFLPVSE MSEAYIRDAR EHFKVGQTLS VTIVSCDPEN RKMRVGCREQ
660 670 680 690 700
SWDAKRLERF ENIKAGSVLS GIVLQKTEDS VIVDLGDKVT GVITLGQLCD
710 720 730 740 750
GDLNKCSKVM NKLRASTKLA EVLVLRKDTS KKLISLSLKK SLVEAAKENR
760 770 780 790 800
MPINITDLKE GIKYFGFVRN ATTFGVFVEF CDGLVALVPK AYISEEYVPV
810 820 830 840 850
PSAVYKPQQS VTCVCLSVEL SQEKAFMSFK PLAQKQEKAV EFMESKYDID
860 870 880 890 900
NPVDETIKKT YDYVAGKITW AVVTSAKASQ LNVDLAANVH GRVDVSEVFD
910 920 930 940 950
NFGEIVDPNK PLKRFHKGDK IRVRVLGIHD SRNHKFLPIS HRVSPKQFLE
960 970 980 990 1000
LSVRPSILNM EPFSMKEPQF KKGDEVTGFV NNVSKECVWV SLTPSVNGRI
1010 1020 1030 1040 1050
PILDLTTDVK ELNSLQKHFF LGKAIKCYVV NAEDSITLSA IGPLQGFENL
1060 1070 1080 1090 1100
TPGSRLVGKV TNVNEAGAIL QLPGHMSGRV SRIDMFDDYD ILPETKFTRN
1110 1120 1130 1140 1150
NLVGVCVLSV DVPNRKVALS ARNSRTQSQP VEIKDKEINS VDDLKIGDIC
1160 1170 1180 1190 1200
RGFVCNVANQ GLFVTIGHNL IARVKIGELF DTFIKDWKPH FHVNQLVKGS
1210 1220 1230 1240 1250
IVGIDNDSKR IEMSLKQSKI KDSSEITKTF ADIAVGSNLD GTVVKVGDYG
1260 1270 1280 1290 1300
VLIRIDGTDN IVGLCHKSEI ADAVVLNISK LYSSGDKVRA HVLDVDSEKR
1310 1320 1330 1340 1350
RIALGLKSSY FDSDSDISMS DNEEDVEMRS EDQSDTSESE VGSKDDVQSE
1360 1370 1380 1390 1400
EVENLESAGD EDEEEEPSAL QANGFDWTDG STVFDKLADD TEDSEDEEDE
1410 1420 1430 1440 1450
EPKRKKSKSD RFDDEEKDLD EIPSTAADFE RQLLSSPNSS LLWISYMAYH
1460 1470 1480 1490 1500
LNLNELQEAR EVGKRALSTI NYREEDEKLN VWMALLNLEV AYGTEDSLKE
1510 1520 1530 1540 1550
VFKEACAYCD ALIVYEKLCG ILIKGGKVDL ADEYMQLMLK NFKQVPSVWI
1560 1570 1580 1590 1600
QYATFLLNND KAEKAHGLLE RSLQSLPKSE HVGIIEKFAI LEFKNGDPER
1610 1620 1630 1640 1650
GRTIFEGLLS SYPKRLDLWN VLIDMEMKQD DPSIVRRLFQ RLLALNLSTK
1660 1670 1680 1690
KAKFAFKKWL AYEKNIGDDE GAEQVKRRAI EYVSESHSEN
Length:1,690
Mass (Da):187,524
Last modified:November 1, 1998 - v1
Checksum:i42629B8347DACCD6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329672 Genomic DNA. Translation: CAA21087.1.
PIRiT40847.
RefSeqiNP_587890.1. NM_001022882.2.

Genome annotation databases

EnsemblFungiiSPCC1183.07.1; SPCC1183.07.1:pep; SPCC1183.07.
GeneIDi2538897.
KEGGispo:SPCC1183.07.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329672 Genomic DNA. Translation: CAA21087.1.
PIRiT40847.
RefSeqiNP_587890.1. NM_001022882.2.

3D structure databases

ProteinModelPortaliO74835.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi275475. 8 interactors.
IntActiO74835. 1 interactor.

PTM databases

iPTMnetiO74835.

Proteomic databases

MaxQBiO74835.
PRIDEiO74835.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPCC1183.07.1; SPCC1183.07.1:pep; SPCC1183.07.
GeneIDi2538897.
KEGGispo:SPCC1183.07.

Organism-specific databases

EuPathDBiFungiDB:SPCC1183.07.
PomBaseiSPCC1183.07. rrp5.

Phylogenomic databases

HOGENOMiHOG000167551.
InParanoidiO74835.
KOiK14792.
OMAiKEWKDSF.
OrthoDBiEOG092C03ZV.
PhylomeDBiO74835.

Enzyme and pathway databases

ReactomeiR-SPO-6791226. Major pathway of rRNA processing in the nucleolus and cytosol.

Miscellaneous databases

PROiO74835.

Family and domain databases

Gene3Di1.25.40.10. 1 hit.
InterProiIPR003107. HAT.
IPR012340. NA-bd_OB-fold.
IPR022967. S1_dom.
IPR003029. S1_domain.
IPR008847. Suf.
IPR011990. TPR-like_helical_dom.
[Graphical view]
PfamiPF00575. S1. 5 hits.
PF05843. Suf. 1 hit.
[Graphical view]
SMARTiSM00386. HAT. 6 hits.
SM00316. S1. 13 hits.
[Graphical view]
SUPFAMiSSF48452. SSF48452. 1 hit.
SSF50249. SSF50249. 12 hits.
PROSITEiPS50126. S1. 12 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRRP5_SCHPO
AccessioniPrimary (citable) accession number: O74835
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: November 1, 1998
Last modified: November 30, 2016
This is version 103 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.