Reviewed,
UniProtKB/Swiss-Prot O74833 (DNLI4_SCHPO)
Last modified
November 25, 2008.
Version 47.
History...
Clusters with 100%,
90%,
50% identity |
Documents (2) |
Third-party data |
Customize display | text xml rdf/xml gff fasta |
Names and origin
| Protein names | Recommended name: DNA ligase 4 EC=6.5.1.1 Alternative name(s): DNA ligase IV Polydeoxyribonucleotide synthase [ATP] 4 | ||||
| Gene names |
| ||||
| Organism | Schizosaccharomyces pombe (Fission yeast) [Complete proteome] | ||||
| Taxonomic identifier | 4896 [NCBI] | ||||
| Taxonomic lineage | Eukaryota › Fungi › Dikarya › Ascomycota › Taphrinomycotina › Schizosaccharomycetes › Schizosaccharomycetales › Schizosaccharomycetaceae › Schizosaccharomyces |
Protein attributes
| Sequence length | 923 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Evidence at transcript level. |
General annotation (Comments)
| Function | Involved in ds DNA break repair. |
| Catalytic activity | ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m). |
| Subcellular location | NucleusBy similarity. |
| Sequence similarities | Belongs to the ATP-dependent DNA ligase family. Contains 1 BRCT domain. |
Ontologies
Keywords | |
|---|---|
| Biological process | DNA damage DNA recombination DNA repair DNA replication |
| Cellular component | Nucleus |
| Ligand | ATP-binding Nucleotide-binding |
| Molecular function | Ligase |
| Technical term | Complete proteome |
Gene Ontology (GO) | |
| Biological process | DNA recombination Inferred from electronic annotation. Source: InterPro DNA replicationInferred from electronic annotation. Source: InterPro double-strand break repair via nonhomologous end joining Ref.2Inferred from mutant phenotype. Source: GeneDB_SPombe |
| Cellular component | DNA ligase IV complex Traceable author statement. Source: GeneDB_SPombe |
| Molecular function | ATP binding Inferred from electronic annotation. Source: InterPro DNA ligase (ATP) activityInferred from electronic annotation. Source: InterPro |
| Complete GO annotation... | |
Sequence annotation (Features)
Sequences
| ||||||||||||||||||
References
| « Hide 'large scale' references | |
| [1] | "The genome sequence of Schizosaccharomyces pombe." Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M. Nurse P.Nature 415:871-880(2002) [PubMed: 11859360] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 38366 / 972. |
| [2] | "Protection of telomeres by the Ku protein in fission yeast." Baumann P., Cech T.R. Mol. Biol. Cell 11:3265-3275(2000) [PubMed: 11029034] [Abstract] Cited for: FUNCTION. |
Cross-references
Sequence databases | |
|---|---|
| CU329672 Genomic DNA. Translation: CAA21085.2. | |
| PIR | T40845. |
| RefSeq | NP_587888.1. |
3D structure databases | |
| ModBase | Search... |
Genome annotation databases | |
| GeneID | 2539042. |
| KEGG | spo:SPCC1183.05c. |
| NMPDR | fig|4896.1.peg.226. |
Organism-specific databases | |
| GeneDB_Spombe | SPCC1183.05c. |
Gene expression databases | |
| ArrayExpress | O74833. |
Family and domain databases | |
| InterPro | IPR001357. BRCT. IPR000977. DNA_ligase. IPR012309. DNA_ligase_A_C. IPR012310. DNA_ligase_A_M. IPR016059. DNA_ligase_CS. IPR012340. NA-bd_OB-fold. [Graphical view] |
| Gene3D | G3DSA:2.40.50.140. OB_NA_bd_sub. 1 hit. |
| Pfam | PF00533. BRCT. 1 hit. PF04679. DNA_ligase_A_C. 1 hit. PF01068. DNA_ligase_A_M. 1 hit. [Graphical view] |
| TIGRFAMs | TIGR00574. dnl1. 1 hit. |
| PROSITE | PS50172. BRCT. 1 hit. PS00697. DNA_LIGASE_A1. 1 hit. PS00333. DNA_LIGASE_A2. False negative. PS50160. DNA_LIGASE_A3. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | DNLI4_SCHPO | ||||||||
| Accession | Primary (citable) accession number: O74833 | ||||||||
| Entry history |
| ||||||||
| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | FPAP (Fungal Proteome Annotation Project) | ||||||||
Relevant documents
| Schizosaccharomyces pombe Schizosaccharomyces pombe: entries and gene names |
| SIMILARITY comments Index of protein domains and families |

Clusters with


