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Protein

Putative glutathione S-transferase C1183.02

Gene

SPCC1183.02

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Involved in the oxidative stress response and detoxification.By similarity

Catalytic activityi

RX + glutathione = HX + R-S-glutathione.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Transferase

Enzyme and pathway databases

ReactomeiR-SPO-156842. Eukaryotic Translation Elongation.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative glutathione S-transferase C1183.02 (EC:2.5.1.18)
Gene namesi
ORF Names:SPCC1183.02
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome III

Organism-specific databases

EuPathDBiFungiDB:SPCC1183.02.
PomBaseiSPCC1183.02.

Subcellular locationi

GO - Cellular componenti

  • cytoplasm Source: GO_Central
  • cytosol Source: PomBase
  • nucleus Source: GO_Central
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003160371 – 220Putative glutathione S-transferase C1183.02Add BLAST220

Proteomic databases

MaxQBiO74830.
PRIDEiO74830.

Interactioni

Protein-protein interaction databases

BioGridi275588. 4 interactors.
MINTiMINT-4681071.

Structurei

3D structure databases

ProteinModelPortaliO74830.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2 – 81GST N-terminalAdd BLAST80
Domaini89 – 216GST C-terminalAdd BLAST128

Sequence similaritiesi

Belongs to the GST superfamily.Curated
Contains 1 GST C-terminal domain.Curated
Contains 1 GST N-terminal domain.Curated

Phylogenomic databases

InParanoidiO74830.
KOiK03233.
OMAiFKESATR.
OrthoDBiEOG092C4JVS.
PhylomeDBiO74830.

Family and domain databases

Gene3Di1.20.1050.10. 1 hit.
3.40.30.10. 1 hit.
InterProiIPR010987. Glutathione-S-Trfase_C-like.
IPR004045. Glutathione_S-Trfase_N.
IPR004046. GST_C.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PfamiPF00043. GST_C. 1 hit.
PF02798. GST_N. 1 hit.
[Graphical view]
SUPFAMiSSF47616. SSF47616. 1 hit.
SSF52833. SSF52833. 1 hit.
PROSITEiPS50405. GST_CTER. 1 hit.
PS50404. GST_NTER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O74830-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFLGTLYSFK TNTRTVCLLE LAKLLDLQVD LVETYPHKFS ADLAAKFPLQ
60 70 80 90 100
KLPVFIGADG FELSEVIAIV KYFYEKGKHN DKEGLGPVNE VEEAEMLKWM
110 120 130 140 150
CFINFDIVTP QNVRPWVGMF RGNIPYEEKP FKESATRAID SLKIPNELVK
160 170 180 190 200
DRTYLVGDRF TLADLFFGSL LRIFFNSIID EKTRKELPHL TRYYITMFHQ
210 220
AKLETYFPLE LPLTVTVAKK
Length:220
Mass (Da):25,504
Last modified:November 1, 1998 - v1
Checksum:i4BB915229C886213
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329672 Genomic DNA. Translation: CAA21082.1.
PIRiT40842.
RefSeqiNP_587885.1. NM_001022877.2.

Genome annotation databases

EnsemblFungiiSPCC1183.02.1; SPCC1183.02.1:pep; SPCC1183.02.
GeneIDi2539015.
KEGGispo:SPCC1183.02.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329672 Genomic DNA. Translation: CAA21082.1.
PIRiT40842.
RefSeqiNP_587885.1. NM_001022877.2.

3D structure databases

ProteinModelPortaliO74830.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi275588. 4 interactors.
MINTiMINT-4681071.

Proteomic databases

MaxQBiO74830.
PRIDEiO74830.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPCC1183.02.1; SPCC1183.02.1:pep; SPCC1183.02.
GeneIDi2539015.
KEGGispo:SPCC1183.02.

Organism-specific databases

EuPathDBiFungiDB:SPCC1183.02.
PomBaseiSPCC1183.02.

Phylogenomic databases

InParanoidiO74830.
KOiK03233.
OMAiFKESATR.
OrthoDBiEOG092C4JVS.
PhylomeDBiO74830.

Enzyme and pathway databases

ReactomeiR-SPO-156842. Eukaryotic Translation Elongation.

Miscellaneous databases

PROiO74830.

Family and domain databases

Gene3Di1.20.1050.10. 1 hit.
3.40.30.10. 1 hit.
InterProiIPR010987. Glutathione-S-Trfase_C-like.
IPR004045. Glutathione_S-Trfase_N.
IPR004046. GST_C.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PfamiPF00043. GST_C. 1 hit.
PF02798. GST_N. 1 hit.
[Graphical view]
SUPFAMiSSF47616. SSF47616. 1 hit.
SSF52833. SSF52833. 1 hit.
PROSITEiPS50405. GST_CTER. 1 hit.
PS50404. GST_NTER. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiYC12_SCHPO
AccessioniPrimary (citable) accession number: O74830
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: November 1, 1998
Last modified: October 5, 2016
This is version 102 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.