Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Uncharacterized carboxypeptidase C337.07c

Gene

SPBC337.07c

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Cofactori

Zn2+By similarityNote: Binds 1 zinc ion per subunit.By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi248 – 2481ZincBy similarity
Metal bindingi251 – 2511ZincBy similarity
Metal bindingi377 – 3771ZincBy similarity
Active sitei429 – 4291Proton donorBy similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Carboxypeptidase, Hydrolase, Metalloprotease, Protease

Keywords - Ligandi

Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized carboxypeptidase C337.07c (EC:3.4.17.-)
Gene namesi
ORF Names:SPBC337.07c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome II

Organism-specific databases

EuPathDBiFungiDB:SPBC337.07c.
PomBaseiSPBC337.07c.

Subcellular locationi

GO - Cellular componenti

  • endoplasmic reticulum Source: PomBase
  • extracellular space Source: GO_Central
Complete GO annotation...

Keywords - Cellular componenti

Endoplasmic reticulum

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2828Sequence analysisAdd
BLAST
Chaini29 – 497469Uncharacterized carboxypeptidase C337.07cPRO_0000310336Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi317 ↔ 337By similarity

Keywords - PTMi

Disulfide bond

Proteomic databases

MaxQBiO74818.

Interactioni

Protein-protein interaction databases

BioGridi277582. 2 interactions.
MINTiMINT-4680965.

Structurei

3D structure databases

ProteinModelPortaliO74818.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase M14 family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

InParanoidiO74818.
KOiK08783.
OMAiYVYTWET.
OrthoDBiEOG7Z0K5M.
PhylomeDBiO74818.

Family and domain databases

InterProiIPR000834. Peptidase_M14.
[Graphical view]
PfamiPF00246. Peptidase_M14. 1 hit.
[Graphical view]
PRINTSiPR00765. CRBOXYPTASEA.
SMARTiSM00631. Zn_pept. 1 hit.
[Graphical view]
PROSITEiPS00132. CARBOXYPEPT_ZN_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

O74818-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAYNKSLKSL VFILLASQIV FVLFLCYGKS SRELGVKWNS DIRSWMTSYV
60 70 80 90 100
GFNGETAAIS EEQLIWAEKI PDYNEEIVVR LHLEEENNLS DILQKAQSQN
110 120 130 140 150
LDIWDYNFDH VDLRLKEENF DFWKSQYRSD ILINNLTETL FESIVPDTTN
160 170 180 190 200
SPFSTEAFLQ AVENGHLNHE MFTSFTDIFF KSYQNLESIN SWLRLMASLY
210 220 230 240 250
KDLSELVPVG ITAEGRTILG LKLNGRHPSD NGEKIRNKKV IIIQGGSHAR
260 270 280 290 300
EWIGIPSVCY AAWQLLAKYD SDGHVRKLLD KFEWIFIPVL NVDGYEYTWS
310 320 330 340 350
NDRLWSKNRQ PLNNSECFGI NLDANWAFGF NGNIDPCSNE YGGLSPFQAN
360 370 380 390 400
ETMALFNLIT ESLSQEQKKV VGFLDVHSYS QSVLWPYAYT CDLFPPDTEN
410 420 430 440 450
FEELAIGLVK ELHRVNSRYY TYQQACIPYD GFHKHYLPGT AIDWVYFAAD
460 470 480 490
VAWPFNIRLR DMGDYGYLLP AKQIVPTAKE FFAMILYYGE FIAEYAF
Length:497
Mass (Da):57,486
Last modified:November 1, 1998 - v1
Checksum:iCE3B1C0EECC142CF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329671 Genomic DNA. Translation: CAA21277.1.
PIRiT40260.
RefSeqiNP_595408.1. NM_001021315.2.

Genome annotation databases

EnsemblFungiiSPBC337.07c.1; SPBC337.07c.1:pep; SPBC337.07c.
GeneIDi2541067.
KEGGispo:SPBC337.07c.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329671 Genomic DNA. Translation: CAA21277.1.
PIRiT40260.
RefSeqiNP_595408.1. NM_001021315.2.

3D structure databases

ProteinModelPortaliO74818.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi277582. 2 interactions.
MINTiMINT-4680965.

Proteomic databases

MaxQBiO74818.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPBC337.07c.1; SPBC337.07c.1:pep; SPBC337.07c.
GeneIDi2541067.
KEGGispo:SPBC337.07c.

Organism-specific databases

EuPathDBiFungiDB:SPBC337.07c.
PomBaseiSPBC337.07c.

Phylogenomic databases

InParanoidiO74818.
KOiK08783.
OMAiYVYTWET.
OrthoDBiEOG7Z0K5M.
PhylomeDBiO74818.

Miscellaneous databases

PROiO74818.

Family and domain databases

InterProiIPR000834. Peptidase_M14.
[Graphical view]
PfamiPF00246. Peptidase_M14. 1 hit.
[Graphical view]
PRINTSiPR00765. CRBOXYPTASEA.
SMARTiSM00631. Zn_pept. 1 hit.
[Graphical view]
PROSITEiPS00132. CARBOXYPEPT_ZN_1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The genome sequence of Schizosaccharomyces pombe."
    Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.
    , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
    Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 972 / ATCC 24843.
  2. "ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe."
    Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S., Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S., Yoshida M.
    Nat. Biotechnol. 24:841-847(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiYBJ7_SCHPO
AccessioniPrimary (citable) accession number: O74818
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 13, 2007
Last sequence update: November 1, 1998
Last modified: July 6, 2016
This is version 85 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Peptidase families
    Classification of peptidase families and list of entries
  2. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.