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Protein

Mitochondrial GTPase 1

Gene

mtg1

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Mitochondrial GTPase involved in assembly of the large ribosomal subunit (By similarity). Plays a role in expression of the mitochondrial translational machinery (By similarity).By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei207 – 2071GTP; via amide nitrogenBy similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi70 – 734GTPBy similarity
Nucleotide bindingi155 – 1606GTPBy similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Ligandi

GTP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Mitochondrial GTPase 1
Gene namesi
Name:mtg1
ORF Names:SPBC25B2.04c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome II

Organism-specific databases

EuPathDBiFungiDB:SPBC25B2.04c.
PomBaseiSPBC25B2.04c. mtg1.

Subcellular locationi

  • Mitochondrion inner membrane By similarity; Peripheral membrane protein By similarity

GO - Cellular componenti

  • mitochondrial inner membrane Source: PomBase
  • mitochondrion Source: PomBase
Complete GO annotation...

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini? – 328Mitochondrial GTPase 1PRO_0000280264
Transit peptidei1 – ?MitochondrionSequence analysis

Proteomic databases

MaxQBiO74776.

Interactioni

Protein-protein interaction databases

BioGridi276970. 25 interactions.

Structurei

3D structure databases

ProteinModelPortaliO74776.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini23 – 211189CP-type GPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.PROSITE-ProRule annotation
Contains 1 CP-type G (guanine nucleotide-binding) domain.PROSITE-ProRule annotation

Keywords - Domaini

Transit peptide

Phylogenomic databases

HOGENOMiHOG000173971.
InParanoidiO74776.
KOiK19828.
OMAiPDHIVGE.
OrthoDBiEOG092C2YFB.
PhylomeDBiO74776.

Family and domain databases

Gene3Di1.10.1580.10. 1 hit.
3.40.50.300. 1 hit.
InterProiIPR030378. G_CP_dom.
IPR023179. GTP-bd_ortho_bundle.
IPR006073. GTP_binding_domain.
IPR016478. GTPase_MTG1.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF01926. MMR_HSR1. 1 hit.
[Graphical view]
PIRSFiPIRSF006230. MG442. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS51721. G_CP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

O74776-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAFVARQTFE YQMPSTWYPG HMNKTLKRLK NLTSSNDIFV EVRDARIPLT
60 70 80 90 100
SRNYVMEDFL NKKNRIIVYN KCDLADTFHT KAKVSKHRIQ NLAQQFQNVE
110 120 130 140 150
CWFKETSTPE KSAFITPYVS KAPYFAKELL RLIRTLVDQA SANGRVYVYF
160 170 180 190 200
VGMPNTGKSS ILNSLRNVAL RKSKSAIVGN YPGVTKRISE IVRLFNDMDV
210 220 230 240 250
YMLDTPGIMT PSITKPEDML KLSLVGCVKE GIVHPVTVVD YLLFHLNRID
260 270 280 290 300
PSLYSKWSLP TNDVDEFLQN TAYKARKLTK GGFDENFVSN YVIQQYRIGR
310 320
LGRFQLDTID KNELLIRLHN EQNKKNAK
Length:328
Mass (Da):37,871
Last modified:November 1, 1998 - v1
Checksum:iB1C21FEA0F74FE04
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329671 Genomic DNA. Translation: CAA21262.1.
PIRiT39980.
RefSeqiNP_596072.1. NM_001021984.2.

Genome annotation databases

EnsemblFungiiSPBC25B2.04c.1; SPBC25B2.04c.1:pep; SPBC25B2.04c.
GeneIDi2540442.
KEGGispo:SPBC25B2.04c.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329671 Genomic DNA. Translation: CAA21262.1.
PIRiT39980.
RefSeqiNP_596072.1. NM_001021984.2.

3D structure databases

ProteinModelPortaliO74776.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi276970. 25 interactions.

Proteomic databases

MaxQBiO74776.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPBC25B2.04c.1; SPBC25B2.04c.1:pep; SPBC25B2.04c.
GeneIDi2540442.
KEGGispo:SPBC25B2.04c.

Organism-specific databases

EuPathDBiFungiDB:SPBC25B2.04c.
PomBaseiSPBC25B2.04c. mtg1.

Phylogenomic databases

HOGENOMiHOG000173971.
InParanoidiO74776.
KOiK19828.
OMAiPDHIVGE.
OrthoDBiEOG092C2YFB.
PhylomeDBiO74776.

Miscellaneous databases

PROiO74776.

Family and domain databases

Gene3Di1.10.1580.10. 1 hit.
3.40.50.300. 1 hit.
InterProiIPR030378. G_CP_dom.
IPR023179. GTP-bd_ortho_bundle.
IPR006073. GTP_binding_domain.
IPR016478. GTPase_MTG1.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF01926. MMR_HSR1. 1 hit.
[Graphical view]
PIRSFiPIRSF006230. MG442. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS51721. G_CP. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiMTG1_SCHPO
AccessioniPrimary (citable) accession number: O74776
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 20, 2007
Last sequence update: November 1, 1998
Last modified: September 7, 2016
This is version 92 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.